Pantoprazole is a prescription drug used to treat inflammation of the esophagus (esophagitis), gastroesophageal reflux disease (GERD), and disorders in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) that works by decreasing the production of acid in the stomach. Pantoprazole is a generic medication and is approved by the U.S. Food and Drug Administration (FDA). The average cash price of Pantoprazole is $143.05 for 30, 40mg tablet delayed releases, but you may be able to use a free Pantoprazole prescription coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $7.28 for 30, 40mg tablet delayed releases.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/06/2025
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Pantoprazole is a prescription drug used to treat inflammation of the esophagus (esophagitis), gastroesophageal reflux disease (GERD), and disorders in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) that works by decreasing the production of acid in the stomach. Pantoprazole is a generic medication and is approved by the U.S. Food and Drug Administration (FDA). The average cash price of Pantoprazole is $143.05 for 30, 40mg tablet delayed releases, but you may be able to use a free Pantoprazole prescription coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $7.28 for 30, 40mg tablet delayed releases.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Protonix Retail Price | Pantoprazole Sodium Retail Price | Pantoprazole Sodium SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $84.77 | $30.71 |
| Walmart | - | $32.10 | $11.40 |
| Walgreens | $467.70 | $65.15 | $45.93 |
| Kroger Pharmacy | $548.40 | $82.20 | $5.01 |
| Albertsons Pharmacy | - | $118.67 | $19.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Pantoprazole is a prescription drug used to treat inflammation of the esophagus (esophagitis), gastroesophageal reflux disease (GERD), and disorders in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) that works by decreasing the production of acid in the stomach. Pantoprazole is a generic medication and is approved by the U.S. Food and Drug Administration (FDA). The average cash price of Pantoprazole is $143.05 for 30, 40mg tablet delayed releases, but you may be able to use a free Pantoprazole prescription coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $7.28 for 30, 40mg tablet delayed releases.
People without insurance, or cash-paying customers, pay an average price for Pantoprazole of $143.05 for 30, 40mg tablet delayed releases. The cash price of Pantoprazole can vary depending on the pharmacy location and quantity prescribed. A SingleCare discount savings card may help lower the cash price of {{drug} at participating U.S. pharmacies. Visit the SingleCare website for a prescription discount card or coupon to start saving on your prescription prices today.
Pantoprazole is a generic drug that is usually covered by insurance plans. The copay cost of Pantoprazole with private insurance varies by factors such as the plan, the Pantoprazole dosage prescribed, and the quantity prescribed. Other factors, such as coverage stage, can also affect the price of Pantoprazole with insurance. Consult your insurance company or pharmacist to determine your out-of-pocket medication costs for Pantoprazole. Pantoprazole costs may be lower with SingleCare than with insurance. Bring your SingleCare Pantoprazole coupon to the pharmacy counter and ask a pharmacy staff member to calculate the savings with your coupon compared to the cost with insurance. You can also contact your health insurance plan for the most recent information on pricing estimates.
Medicare prescription drug plans usually cover Pantoprazole. The cost of Pantoprazole with Medicare coverage varies depending on the plan, coverage stage, and the quantity prescribed. Contact your insurance provider or pharmacist to determine your out-of-pocket costs, such as a copay or coinsurance amount, for Pantoprazole. You can apply for patient assistance programs if you have an unaffordable copay and have trouble paying for your prescription.
Pantoprazole is a generic prescription drug produced by various pharmaceutical companies, including Sun Pharmaceuticals, Amneal Pharmaceuticals, and Mylan Pharmaceuticals. The brand name of Pantoprazole is Protonix. The generic and brand-name versions are available as a delayed-release oral tablet, granules for delayed-release oral suspension, and powder for reconstitution for intravenous (IV) injection.
Pantoprazole is a prescription medication used to treat individuals with GERD, erosive esophagitis, and hypersecretory conditions, such as Zollinger-Ellison syndrome. It may also be used to prevent or treat ulcers in the stomach or intestines. Pantoprazole is sometimes prescribed to prevent ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs).
Pantoprazole belongs to a class of medications called proton pump inhibitors. It works by blocking the activity of the acid-producing cells that line the stomach. By decreasing the amount of stomach acid produced in the stomach, Pantoprazole can help treat and prevent damage caused by certain digestive disorders.
Pantoprazole is usually taken once or twice daily, depending on the condition being treated. It is available as an oral delayed-release tablet and delayed-release suspension. Pantoprazole can also be administered as an IV injection or infusion.
The most common side effects of Pantoprazole are diarrhea, nausea, vomiting, headache, abdominal pain, gas, joint pain, and dizziness. Serious side effects are rare but may include kidney problems, severe diarrhea, bone fractures, lupus, low magnesium levels, low vitamin B12 levels, stomach growths, and severe skin or allergic reactions. High doses and long-term treatment may increase the risk of serious side effects.
Seek immediate medical attention if you experience signs or symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling.
Skin reactions can be severe and life-threatening if left untreated. Seek emergency medical help if you have symptoms of a skin reaction, such as fever, burning eyes, sore throat, skin pain, rash, or blistering or peeling skin.
Before taking this medicine, consult your healthcare provider or pharmacist for more information about possible side effects. Tell your healthcare provider about any medical conditions or other medications you take before starting treatment with Pantoprazole. Having certain medical conditions or taking certain medications may increase the risk of side effects.
Pantoprazole oral delayed-release tablets can be taken with or without food. However, high-fat meals have been shown to decrease the absorption of pantoprazole granules. Therefore, the delayed-release oral suspension form should be taken around 30 minutes before a meal.
Pantoprazole granules should only be administered with apple juice or apple sauce. They should not be mixed with water or other liquids or foods.
Pantoprazole is a generic version of the brand-name drug Protonix. Nexium is a brand-name drug. Nexium contains esomeprazole, which is a proton pump inhibitor that works similarly to Pantoprazole. Both drugs can help treat GERD, ulcers, and hypersecretory conditions. Although they are similar in effectiveness, Pantoprazole and Nexium come in different formulations and strengths. One drug may be preferred over the other depending on other factors, such as cost, insurance coverage, and the condition being treated.
Pantoprazole may cause harm to an unborn baby. Healthcare providers do not typically recommend Pantoprazole while pregnant unless the benefits outweigh the potential risks. Pantoprazole can also pass into breast milk. It is important to consult a healthcare provider for medical advice if you are pregnant or breastfeeding before using Pantoprazole.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved