Pantoprazole Coupons & Prices

Protonix

Pantoprazole is a prescription drug used to treat inflammation of the esophagus (esophagitis), gastroesophageal reflux disease (GERD), and disorders in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) that works by decreasing the production of acid in the stomach. Pantoprazole is a generic medication and is approved by the U.S. Food and Drug Administration (FDA). The average cash price of Pantoprazole is $143.05 for 30, 40mg tablet delayed releases, but you may be able to use a free Pantoprazole prescription coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $7.28 for 30, 40mg tablet delayed releases.

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Pantoprazole coupon at Kroger Pharmacy
$10.28
$ 7.28
$3 off with signupwith signup

Show this free card to your pharmacist.

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Pantoprazole coupon at Harris Teeter Pharmacy
$10.28
$ 7.28
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Pantoprazole coupon at Walmart Neighborhood Market Pharmacy
$14.51
$ 11.51
$3 off with signupwith signup
Pantoprazole coupon at Walmart Pharmacy
$14.51
$ 11.51
$3 off with signupwith signup
Pantoprazole coupon at Food Lion Pharmacy
$ 13.19
Pantoprazole coupon at Walgreens Pharmacy
$17.49
$ 14.49
$3 off with signupwith signup
$20.66
$ 17.66
$3 off with signupwith signup
$24.87
$ 21.87
$3 off with signupwith signup
$ 21.99

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/06/2025

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About Pantoprazole

Pantoprazole is a prescription drug used to treat inflammation of the esophagus (esophagitis), gastroesophageal reflux disease (GERD), and disorders in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) that works by decreasing the production of acid in the stomach. Pantoprazole is a generic medication and is approved by the U.S. Food and Drug Administration (FDA). The average cash price of Pantoprazole is $143.05 for 30, 40mg tablet delayed releases, but you may be able to use a free Pantoprazole prescription coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $7.28 for 30, 40mg tablet delayed releases.

Pantoprazole Price History & Information

Price History for Pantoprazole Sodium (Generic) & Protonix (Brand)

30 count, tablet delayed release, 40mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Pantoprazole Sodium (Generic) & Protonix (Brand)

30 count, tablet delayed release, 40mg
PharmacyProtonix Retail PricePantoprazole Sodium Retail PricePantoprazole Sodium SingleCare Price
CVS Pharmacy-$84.77$30.71
Walmart-$32.10$11.40
Walgreens$467.70$65.15$45.93
Kroger Pharmacy$548.40$82.20$5.01
Albertsons Pharmacy-$118.67$19.20

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Pantoprazole

Pantoprazole is a prescription drug used to treat inflammation of the esophagus (esophagitis), gastroesophageal reflux disease (GERD), and disorders in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) that works by decreasing the production of acid in the stomach. Pantoprazole is a generic medication and is approved by the U.S. Food and Drug Administration (FDA). The average cash price of Pantoprazole is $143.05 for 30, 40mg tablet delayed releases, but you may be able to use a free Pantoprazole prescription coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $7.28 for 30, 40mg tablet delayed releases.

Pantoprazole FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Pantoprazole cost without insurance?

People without insurance, or cash-paying customers, pay an average price for Pantoprazole of $143.05 for 30, 40mg tablet delayed releases. The cash price of Pantoprazole can vary depending on the pharmacy location and quantity prescribed. A SingleCare discount savings card may help lower the cash price of {{drug} at participating U.S. pharmacies. Visit the SingleCare website for a prescription discount card or coupon to start saving on your prescription prices today.

How much does Pantoprazole cost with insurance?

Pantoprazole is a generic drug that is usually covered by insurance plans. The copay cost of Pantoprazole with private insurance varies by factors such as the plan, the Pantoprazole dosage prescribed, and the quantity prescribed. Other factors, such as coverage stage, can also affect the price of Pantoprazole with insurance. Consult your insurance company or pharmacist to determine your out-of-pocket medication costs for Pantoprazole. Pantoprazole costs may be lower with SingleCare than with insurance. Bring your SingleCare Pantoprazole coupon to the pharmacy counter and ask a pharmacy staff member to calculate the savings with your coupon compared to the cost with insurance. You can also contact your health insurance plan for the most recent information on pricing estimates.

Does Medicare cover Pantoprazole, and how much does it cost?

Medicare prescription drug plans usually cover Pantoprazole. The cost of Pantoprazole with Medicare coverage varies depending on the plan, coverage stage, and the quantity prescribed. Contact your insurance provider or pharmacist to determine your out-of-pocket costs, such as a copay or coinsurance amount, for Pantoprazole. You can apply for patient assistance programs if you have an unaffordable copay and have trouble paying for your prescription. 

What is the brand name of Pantoprazole?

Pantoprazole is a generic prescription drug produced by various pharmaceutical companies, including Sun Pharmaceuticals, Amneal Pharmaceuticals, and Mylan Pharmaceuticals. The brand name of Pantoprazole is Protonix. The generic and brand-name versions are available as a delayed-release oral tablet, granules for delayed-release oral suspension, and powder for reconstitution for intravenous (IV) injection. 

What is Pantoprazole?

Pantoprazole is a prescription medication used to treat individuals with GERD, erosive esophagitis, and hypersecretory conditions, such as Zollinger-Ellison syndrome. It may also be used to prevent or treat ulcers in the stomach or intestines. Pantoprazole is sometimes prescribed to prevent ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs).

Pantoprazole belongs to a class of medications called proton pump inhibitors. It works by blocking the activity of the acid-producing cells that line the stomach. By decreasing the amount of stomach acid produced in the stomach, Pantoprazole can help treat and prevent damage caused by certain digestive disorders. 

Pantoprazole is usually taken once or twice daily, depending on the condition being treated. It is available as an oral delayed-release tablet and delayed-release suspension. Pantoprazole can also be administered as an IV injection or infusion.

What are the side effects of Pantoprazole?

The most common side effects of Pantoprazole are diarrhea, nausea, vomiting, headache, abdominal pain, gas, joint pain, and dizziness. Serious side effects are rare but may include kidney problems, severe diarrhea, bone fractures, lupus, low magnesium levels, low vitamin B12 levels, stomach growths, and severe skin or allergic reactions. High doses and long-term treatment may increase the risk of serious side effects. 

Seek immediate medical attention if you experience signs or symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling. 

Skin reactions can be severe and life-threatening if left untreated. Seek emergency medical help if you have symptoms of a skin reaction, such as fever, burning eyes, sore throat, skin pain, rash, or blistering or peeling skin. 

Before taking this medicine, consult your healthcare provider or pharmacist for more information about possible side effects. Tell your healthcare provider about any medical conditions or other medications you take before starting treatment with Pantoprazole. Having certain medical conditions or taking certain medications may increase the risk of side effects. 

Do I take Pantoprazole with food?

Pantoprazole oral delayed-release tablets can be taken with or without food. However, high-fat meals have been shown to decrease the absorption of pantoprazole granules. Therefore, the delayed-release oral suspension form should be taken around 30 minutes before a meal. 

Pantoprazole granules should only be administered with apple juice or apple sauce. They should not be mixed with water or other liquids or foods. 

What is the difference between Pantoprazole and Nexium?

Pantoprazole is a generic version of the brand-name drug Protonix. Nexium is a brand-name drug. Nexium contains esomeprazole, which is a proton pump inhibitor that works similarly to Pantoprazole. Both drugs can help treat GERD, ulcers, and hypersecretory conditions. Although they are similar in effectiveness, Pantoprazole and Nexium come in different formulations and strengths. One drug may be preferred over the other depending on other factors, such as cost, insurance coverage, and the condition being treated. 

Can I take Pantoprazole while pregnant or breastfeeding?

Pantoprazole may cause harm to an unborn baby. Healthcare providers do not typically recommend Pantoprazole while pregnant unless the benefits outweigh the potential risks. Pantoprazole can also pass into breast milk. It is important to consult a healthcare provider for medical advice if you are pregnant or breastfeeding before using Pantoprazole.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Pantoprazole coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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