Acetazolamide ER is a generic extended-release prescription drug that treats glaucoma by reducing the fluid pressure in the eye. Acetazolamide ER blocks a protein responsible for the eye's production of fluid inside the eye. On average, the retail price of Acetazolamide ER is $247.72, but only costs $29.34 with a SingleCare Acetazolamide ER coupon. Many local pharmacies–CVS, Target, Longs Drugs, Walgreens, and Duane Reade–accept SingleCare.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Acetazolamide ER is a generic extended-release prescription drug that treats glaucoma by reducing the fluid pressure in the eye. Acetazolamide ER blocks a protein responsible for the eye's production of fluid inside the eye. On average, the retail price of Acetazolamide ER is $247.72, but only costs $29.34 with a SingleCare Acetazolamide ER coupon. Many local pharmacies–CVS, Target, Longs Drugs, Walgreens, and Duane Reade–accept SingleCare.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Acetazolamide Er Retail Price | Acetazolamide Er SingleCare Price |
|---|---|---|
| CVS Pharmacy | $214.80 | $42.00 |
| Walmart | $88.20 | $56.91 |
| Walgreens | $237.00 | $91.80 |
| Kroger Pharmacy | $146.23 | $38.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Acetazolamide ER is a generic extended-release prescription drug that treats glaucoma by reducing the fluid pressure in the eye. Acetazolamide ER blocks a protein responsible for the eye's production of fluid inside the eye. On average, the retail price of Acetazolamide ER is $247.72, but only costs $29.34 with a SingleCare Acetazolamide ER coupon. Many local pharmacies–CVS, Target, Longs Drugs, Walgreens, and Duane Reade–accept SingleCare.
A prescription will cost around $247.72 for uninsured customers, but the dose prescribed may vary depending on the severity of the underlying condition. With a SingleCare Acetazolamide ER coupon, you will pay $29.34 per 60, 500mg capsules extended release 12 hour for the same prescription of Acetazolamide ER.
Your copay for Acetazolamide ER will vary depending on your plan and the dose prescribed. Ask your pharmacist to compare your insurance copay to your price with a SingleCare Acetazolamide ER coupon. Your SingleCare discount card may save you more money with SingleCare, Acetazolamide ER only costs $29.34.
Acetazolamide ER is usually covered by Medicare prescription drug plans. Patients without Medicare can save money with SingleCare Acetazolamide ER coupons. The price of Acetazolamide ER with a SingleCare discount card is $29.34.
Acetazolamide ER is a generic extended-release prescription drug used to lower pressure in the eye in patients with glaucoma. Acetazolamide ER is a generic alternative to Diamox Sequels, a drug that has been discontinued by its manufacturer due to generic competition. Generic Acetazolamide ER is manufactured by numerous generic drug manufacturers, including Alembic, Heritage, and Taro, among others.
Acetazolamide ER is a generic prescription drug used to treat glaucoma, a condition in which too much fluid inside the eye (intraocular fluid) creates extra pressure inside the eye. The excess pressure damages the optic nerve and, if uncorrected, causes vision loss and ultimately blindness.
Acetazolamide ER belongs to a class of drugs called carbonic anhydrase inhibitors, which block a protein vital to the eye's production of fluid inside the eye. This decreases the production of intraocular fluid. As the amount of fluid in the eye decreases, the pressure goes down
Acetazolamide ER is taken as a tablet once or twice a day. The dose will depend on the severity of the underlying condition.
Although not a complete list, common side effects of Acetazolamide ER include nausea, vomiting, diarrhea, constipation, drowsiness, dizziness, loss of appetite, changes in taste, headache, sensitivity to sunlight, tremor, ringing in the ears, and fatigue. Mental and mood changes include confusion and nervousness. The most serious side effects of Acetazolamide ER include seizures, partial loss of movement, liver problems, kidney stones, and metabolic acidosis, a potentially hazardous condition in which acid builds up in the body. Signs of metabolic acidosis include confusion, irregular heart rate, lack of energy, and vomiting. Allergic reactions to Acetazolamide ER are rare but include rashes, hives, swelling, and trouble breathing. Allergic reactions could involve a severe skin reaction involving a purple rash, blistering, and peeling throughout the body accompanied by fever, sore throat, and swelling. Discontinue use of Acetazolamide ER if you experience an allergic reaction or severe side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved