Afrezza is a brand-name insulin product approved by the FDA for the treatment of Type 1 diabetes and Type 2 diabetes. Afrezza contains human insulin and is considered a rapid-acting insulin. It comes as an inhalation powder that is administered at the beginning of a meal. Actual dosing of Afrezza may be individualized according to a healthcare provider’s directions. There is currently no generic version of Afrezza available. The average cash price of 4 units of single-use Afrezza cartridges is around $590.86 for 1, 90 powder box. A SingleCare prescription discount card may be able to lower the cash price to $465.10 for 1, 90 powder box of generic Afrezza.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Afrezza is a brand-name insulin product approved by the FDA for the treatment of Type 1 diabetes and Type 2 diabetes. Afrezza contains human insulin and is considered a rapid-acting insulin. It comes as an inhalation powder that is administered at the beginning of a meal. Actual dosing of Afrezza may be individualized according to a healthcare provider’s directions. There is currently no generic version of Afrezza available. The average cash price of 4 units of single-use Afrezza cartridges is around $590.86 for 1, 90 powder box. A SingleCare prescription discount card may be able to lower the cash price to $465.10 for 1, 90 powder box of generic Afrezza.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Afrezza Retail Price | Afrezza SingleCare Price |
|---|---|---|
| Walmart | $280.80 | $261.90 |
| Kroger Pharmacy | $567.90 | $468.00 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Afrezza is a brand-name insulin product approved by the FDA for the treatment of Type 1 diabetes and Type 2 diabetes. Afrezza contains human insulin and is considered a rapid-acting insulin. It comes as an inhalation powder that is administered at the beginning of a meal. Actual dosing of Afrezza may be individualized according to a healthcare provider’s directions. There is currently no generic version of Afrezza available. The average cash price of 4 units of single-use Afrezza cartridges is around $590.86 for 1, 90 powder box. A SingleCare prescription discount card may be able to lower the cash price to $465.10 for 1, 90 powder box of generic Afrezza.
The average retail price of Afrezza without insurance is around $590.86. However, the out-of-pocket cost can vary depending on the quantity and dose prescribed. You can use various savings options if you do not have insurance. A free SingleCare Afrezza discount card can lower the price of Afrezza without insurance.
The cost of Afrezza with insurance will depend on the type of plan you have. Contact your insurance plan provider directly to find out what your copay for Afrezza would be. Even with insurance, the cost of Afrezza can be high. Some customers find that a free coupon from SingleCare lowers the cost of their medications to a more affordable price than the cost with insurance. Use a SingleCare Afrezza coupon at participating pharmacies across the United States.
Medicare prescription drug plans may offer coverage for Afrezza. Contact your pharmacy to determine what your Afrezza copay might be with Medicare coverage. If you find that the cost of Afrezza is still high with Medicare, you may choose to use another option, such as a SingleCare discount card to save you more money. Compare options at your local pharmacy.
Afrezza is a brand-name prescription drug. There is currently no generic version of Afrezza available.
Afrezza (regular human insulin) is a brand prescription drug approved for the treatment of type 1 and Type 2 diabetes. This diabetes medication is inhaled and absorbed through the lungs to manage blood sugar levels in those with diabetes. It is a rapid-acting insulin that is typically used at the beginning of each meal. It is not meant to be used as a replacement for basal, or long-acting, insulin. People with Type 1 diabetes will still need to use a long-acting insulin in addition to Afrezza. This type of insulin is not approved for use in treating diabetic ketoacidosis.
Consult with your healthcare provider regarding the correct dosage and frequency for your medical condition. Afrezza comes as a single-use cartridge that is only meant to be opened when used with the inhaler. Consult your doctor or pharmacist for instructions on how to properly administer the medication.
Blood sugar levels may need to be monitored and reported to your doctor regularly. The dosage of this medication is dependent on your medical condition and response to treatment. Do not change brands or types of insulin unless advised by a healthcare professional. Tell your doctor about any changes in diet or exercise while on treatment with Afrezza.
Do not use Afrezza if you have chronic lung problems, such as asthma or COPD. You should also avoid Afrezza if you have allergies to regular human insulin products or any ingredients in Afrezza.
The most common side effects of Afrezza include coughing and a sore throat. Other side effects include low blood sugar, or hypoglycemia. Contact your doctor if you experience signs or symptoms of low blood sugar, such as extreme drowsiness, sweating, hunger, blurred vision, dizziness, or tingling in the extremities.
Your healthcare provider may need to monitor your lung function throughout the duration of treatment with Afrezza to ensure it is right for you. Your doctor may also want to monitor for rare, but serious adverse effects in the lungs, such as lung cancer.
Severe allergic reactions to Afrezza are uncommon. Seek immediate medical attention if you experience hives, rash, trouble breathing, or swelling of the face or throat.
You should contact your provider if you experience muscle cramps, weakness, or an irregular heartbeat, which may be symptoms of low levels of potassium in the blood (hypokalemia).
Seek medical advice from your doctor before starting treatment using Afrezza. This is not a complete list of side effects.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved