Alka-Seltzer is a popular brand-name line of over-the-counter remedies. Original Alka-Seltzer, now called Alka-Seltzer Original Flavor, contains aspirin and two antacids to provide pain relief. Doses are taken every four hours by placing the signature Alka-Seltzer effervescent in a four-ounce glass of water. While antacids are relatively free from side effects, aspirin has risks and so should be used cautiously at home.
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Alka-Seltzer overview
BRAND NAMES:
Alka-Seltzer, Alka-Seltzer Original Flavor
Generic Names:
Aspirin, anhydrous citric acid, sodium bicarbonate
Uses:
Alka-Seltzer relieves minor pain, aches, and fever.
Therapeutic Classes:
Analgesic, antipyretic, nonsteroidal anti-inflammatory drug (NSAID), salicylate, antacid
Forms:
Effervescent tablet
How it’s taken:
By mouth
What is Alka-Seltzer used for?
The manufacturer markets Alka-Seltzer Original Flavor as a pain reliever and fever reducer appropriate for headaches, minor aches and pains, muscle pain, toothache, menstrual pain, colds, and mild fever. Although not indicated on the package, the antacids in Alka-Seltzer can help with heartburn or indigestion, but the drug is not intended to treat those conditions. Use Alka-Seltzer Heartburn Relief instead.
What form(s) does Alka-Seltzer come in?
Effervescent tablets
325 mg aspirin per tablet (Original Flavor) plus the antacids anhydrous citric acid and sodium bicarbonate
What are common Alka-Seltzer dosages?
For pain relief or fever: two original flavor effervescent tablets every four hours as needed
Alka-Seltzer images - What does Alka-Seltzer look like?
Alka-Seltzer
116 tablets effervescent boxAlka-Seltzer
12 tablets effervescent boxAlka-Seltzer
24 tablets effervescent boxAlka-Seltzer
36 tablets effervescent box
How to take Alka-Seltzer
Follow the instructions printed on the package.
Dissolve the tablets fully in four ounces of water. Drink all of this mixture right away.
The maximum daily dosage for Alka-Seltzer Original Flavor is eight daily for adults younger than 60 and three daily for adults older than 60.
Store Alka-Seltzer Original Flavor at room temperature. Protect from excessive heat.
What to do if you miss a dose of Alka-Seltzer
Take a dose as soon as you remember.
If you take a missed dose, the dosing schedule will reset. Don’t take another dose for four hours.
Do not use extra tablets to make up for a missed dose.
Alka-Seltzer contraindications - Who shouldn't take Alka-Seltzer?
You should not use this medicine if you have had an allergic reaction to aspirin, sodium bicarbonate, or anhydrous citric acid.
Alka-Seltzer warnings
Get medical advice from a healthcare professional before taking Alka-Seltzer Original Flavor if you are pregnant, breastfeeding, or on a sodium-restricted diet.
Talk to a doctor before giving Alka-Seltzer to a child 12 years of age or younger.
Talk to a doctor first if you are taking any prescription drugs or have:
Diabetes
Arthritis
Stomach problems, including bleeding or ulcers
Heart disease
High blood pressure
Liver problems
Asthma
A bleeding disorder
Stop taking Alka-Seltzer Original Flavor and see a healthcare professional if:
Pain persists for longer than 10 days
Fever lasts for longer than three days
Stomach problems occur
New symptoms appear
Ringing in the ears or other hearing issues are experienced
Alka-Seltzer products containing aspirin should never be given to children or adolescents with a viral or suspected viral infection.
Ensure any healthcare professional who treats you knows you are taking aspirin products, particularly before medical or dental procedures.
Alka-Seltzer interactions & what to avoid when taking Alka-Seltzer
To avoid possible drug interactions, tell any doctor who treats you that you are using Alka-Seltzer.
The antacids in Alka-Seltzer can interfere with the body’s ability to absorb many prescription drugs, so check with a doctor before using Alka-Seltzer.
Do not use other NSAIDs, including aspirin, ibuprofen, naproxen, or prescription medications for arthritis.
Talk to a doctor before taking Alka-Seltzer if you’re taking blood thinners or medications that treat diabetes, glaucoma, or gout.
Avoid alcohol when taking aspirin products.
Alka-Seltzer side effects - How does Alka-Seltzer make you feel?
Serious side effects
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Severe stomach pain
Bloody or black, tarry stools
Bloody vomit or vomit that looks like coffee grounds
Feeling faint
Unusual bleeding, bruising, weakness, pale skin
Ringing in your ears that will not stop, problems with hearing
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less serious side effects
Mild stomach pain or heartburn
Nausea
Slight ringing in the ears
Sources:
Alka-Seltzer Original Flavor drug information, DailyMed (NIH National Library of Medicine)
Salicylic acid (aspirin), StatPearls
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