What is Almotriptan Malate? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 31, 2020

Almotriptan Malate overview

BRAND NAMES:

  • Axert

Generic Names:

  • Almotriptan Malate

Uses:

  • Treats migraine headaches.

Therapeutic Classes:

  • Antimigraine

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Almotriptan Malate used for?

What form(s) does Almotriptan Malate come in?

  • Tablet

What are common Almotriptan Malate dosages?

  • Tablet 6.25MG

  • Tablet 12.5MG

Almotriptan Malate images - What does Almotriptan Malate look like?

  • Almotriptan Malate
    12.5mg tablet

  • Almotriptan Malate
    6.25mg tablet

How to take Almotriptan Malate

  • Your doctor will tell you how much medicine to use. Do not use more than directed. Use almotriptan only when you have a migraine.

  • If your headache improves but then comes back, you may take a second dose. Wait at least 2 hours before you take the second dose.

  • If your headache does not improve at all after the first dose, do not take a second dose. Call your doctor.

  • Do not use more than 2 doses in any 24-hour period.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • If your headache does not improve at all after the first dose, do not take a second dose. Call your doctor.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • If your headache improves but then comes back, you may take a second dose. Wait at least 2 hours before you take the second dose.

  • Do not use more than 2 doses in any 24-hour period.

  • Your doctor will tell you how much medicine to use. Do not use more than directed. Use almotriptan only when you have a migraine.

What to do if you miss a dose of Almotriptan Malate

Almotriptan Malate contraindications - Who shouldn't take Almotriptan Malate?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to almotriptan, or if you have certain heart or blood vessel problems.

Almotriptan Malate warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, high blood pressure, high cholesterol, or if you smoke. Tell your doctor if you have ischemic bowel disease, or a family history of heart disease, heart attack, blood circulation problems, or stroke. Tell your doctor if you had an allergic reaction to sulfa drugs.

  • This medicine may cause the following problems: Increased risk for heart attack, angina, or strokeSpasms in the blood vessels, including Raynaud syndromeSerotonin syndrome (more likely if used with medicine to treat depression)High blood pressure

  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

  • Your headaches may become worse if you use headache medicine for 10 or more days per month. Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Numbness or weakness on one side of your body, problems with vision, speech, or walking

  • Pale, cool, or blotchy skin, numbness or tingling in your hands or feet

  • Severe stomach pain, bloody diarrhea, nausea, or vomiting

Almotriptan Malate interactions & what to avoid when taking Almotriptan Malate

  • Do not take almotriptan within 24 hours of taking another migraine headache medicine, such as dihydroergotamine, ergotamine, methysergide, frovatriptan, naratriptan, rizatriptan, sumatriptan, or zolmitriptan.

  • Some medicines can affect how almotriptan works. Tell your doctor if you are taking any of the following: Erythromycin, itraconazole, ketoconazole, ritonavirAn MAO inhibitorMedicine to treat depression, such as citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine

  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

  • Your headaches may become worse if you use headache medicine for 10 or more days per month. Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Almotriptan Malate side effects - How does Almotriptan Malate make you feel?

Serious Side Effects

  • Numbness or weakness on one side of your body, problems with vision, speech, or walking

  • Blurred vision or other vision changes

  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there

  • Severe stomach pain, bloody diarrhea, nausea, or vomiting

  • Fast, slow, or uneven heartbeat

  • Pale, cool, or blotchy skin, numbness or tingling in your hands or feet

  • Chest pain or tightness in your throat, neck, or jaw, trouble breathing, unusual sweating, fainting

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

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