What is Atovaquone: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Atovaquone overview

BRAND NAMES:

  • Mepron, Mepron

Generic Names:

  • Atovaquone

Uses:

  • Treats and prevents pneumonia.

Therapeutic Classes:

  • Antiprotozoal

Forms:

  • Liquid, Tablet

How it’s taken:

  • By mouth

What is Atovaquone used for?

What form(s) does Atovaquone come in

  • Liquid

  • Tablet

What are common Atovaquone doses?

  • Bottle 210ML of 750MG/5ML

  • Box 5ML of 750MG/5ML

Common Atovaquone prescriptions

  • Atovaquone
    210ml of 750mg/5ml bottle

  • Atovaquone
    5ml of 750mg/5ml box

  • Atovaquone
    10ml of 750mg/5ml cup

  • Atovaquone
    5ml of 750mg/5ml cup

How to take Atovaquone

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine should be taken with food to help your body absorb it. Tell your doctor if you are not able to do this.

  • Oral liquid: Foil pouch: Put the contents directly in your mouth or use a dosing spoon or cup. Use 1 pouch for a 5-milliliter (mL) dose. Use 2 pouches for a 10-mL dose.Bottle: Shake the bottle gently before each use.Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • This medicine should be taken with food to help your body absorb it. Tell your doctor if you are not able to do this.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.

  • Oral liquid: Foil pouch: Put the contents directly in your mouth or use a dosing spoon or cup. Use 1 pouch for a 5-milliliter (mL) dose. Use 2 pouches for a 10-mL dose.Bottle: Shake the bottle gently before each use.Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

What to do if you miss a dose of Atovaquone

Atovaquone contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to atovaquone.

Atovaquone warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or stomach or bowel problems.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Fever

Atovaquone interactions

  • Some medicines can affect how atovaquone works. Tell your doctor if you are using any of the following: IndinavirRifabutinRifampinTetracycline

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Atovaquone side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Fever

Less Serious Side Effects

  • Headache

  • Runny or stuffy nose

  • Diarrhea