What is Bacitracin-Polymyxin B: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Bacitracin-Polymyxin B overview

BRAND NAMES:

  • Polycin, AK-Poly-Bac

Generic Names:

  • Bacitracin-Polymyxin B

Uses:

  • Treats eye infections.

Therapeutic Classes:

  • Antibiotic Combination

Forms:

  • Ointment

How it’s taken:

  • Into the eye

What is Bacitracin-Polymyxin B used for?

What form(s) does Bacitracin-Polymyxin B come in

  • Ointment

What are common Bacitracin-Polymyxin B doses?

  • Tube 3.5GM of 500-10000UNIT/GM

Common Bacitracin-Polymyxin B prescriptions

  • Bacitracin-Polymyxin B
    3.5gm of 500-10000unit/gm tube

How to take Bacitracin-Polymyxin B

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • This medicine is not for long-term use.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Ophthalmic routeTo use the ointment: Hold the tip of the tube close to your eye with the other hand. Avoid touching the tip of the tube to your eye or finger. Squeeze a ribbon of ointment into the pocket between your lower lid and eyeball. Close your eyes for 1 to 2 minutes. Wipe the tip with a clean tissue and close the tube tightly. Keep the tube tightly closed when you are not using it.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Ophthalmic routeTo use the ointment: Hold the tip of the tube close to your eye with the other hand. Avoid touching the tip of the tube to your eye or finger. Squeeze a ribbon of ointment into the pocket between your lower lid and eyeball. Close your eyes for 1 to 2 minutes. Wipe the tip with a clean tissue and close the tube tightly. Keep the tube tightly closed when you are not using it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • This medicine is not for long-term use.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

What to do if you miss a dose of Bacitracin-Polymyxin B

Bacitracin-Polymyxin B contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to bacitracin or polymyxin B.

Bacitracin-Polymyxin B warnings

  • This medicine may cause slow healing of the eye.

  • You will need to have your eyes checked regularly if you use the medicine for 10 days or longer. Be sure to keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Tell your doctor if you are pregnant or breastfeeding.

  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.

Bacitracin-Polymyxin B interactions

Bacitracin-Polymyxin B side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Slow healing of the eye

Less Serious Side Effects

  • Redness, pain, swelling, or irritation at the application site

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