What is Ciprodex: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Ciprodex overview

BRAND NAMES:

  • Ciprodex, Cipro HC, Cortisporin, Cortisporin TC, Otovel, Otovel, Otovel, Ciprodex

Generic Names:

  • Ciprofloxacin-Dexamethasone

Uses:

  • Treats infections of the ear canal, minor swelling of the ear, and other ear problems., Treats ear infections caused by bacteria. This medicine contains a quinolone antibiotic and a corticosteroid.

Therapeutic Classes:

  • Antibacterial, Anti-Infective/Anti-Inflammatory Combination, Antibacterial, Anti-Infective/Anti-Inflammatory Combination

Forms:

  • Liquid, Drop, Liquid, Drop

How it’s taken:

  • Into the ear, Into the ear

What is Ciprodex used for?

Ciprodex is a medication used to treat bacterial ear infections. Ciprodex contains a quinolone-type antibiotic (ciprofloxacin) and a steroid (dexamethasone). This medication is prepared as ear drops. Ciprodex is a brand version of the combination drug ciprofloxacin HCL/dexamethasone. The components of this drug have been available for years. In the treatment of ear infections, Ciprodex use is common.

What form(s) does Ciprodex come in

  • Liquid

  • Drop

  • Liquid

  • Drop

What are common Ciprodex doses?

  • Bottle 7.5ML of 0.3-0.1%

Common Ciprodex prescriptions

  • Ciprodex
    7.5ml of 0.3-0.1% bottle

How to take Ciprodex

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Otic routeUse this medicine only in your ear.

  • Otic routeYou may warm the drops by holding the unopened bottle in your hands for a few minutes. Cold drops might make you dizzy.

  • Shake the medicine well just before you use it.

  • Otic routeRemove the cap. Do not let the tip of the dropper touch anything, including your ear.

  • Otic routeLie down or tilt your head to the side. For a child, gently pull the child€™s earlobe down and back to straighten the child€™s ear canal. For an adult, gently pull the earlobe up and back to straighten the ear canal.

  • Otic routeDrop the prescribed number of drops into the ear. Keep the ear tilted up for a few minutes or put a cotton ball into your ear.

  • Middle ear infection: Gently fold in the flap of skin at the front of the ear after you put in the drops. Let go of the flap, then fold it in again. Do this 5 times with a pumping motion. This helps move the medicine through the tube and into the middle ear.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Otic routeKeep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

  • Otic routeLie down or tilt your head to the side. For a child, gently pull the child€™s earlobe down and back to straighten the child€™s ear canal. For an adult, gently pull the earlobe up and back to straighten the ear canal.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Shake the medicine well just before you use it.

  • Otic routeDrop the prescribed number of drops into the ear. Keep the ear tilted up for a few minutes or put a cotton ball into your ear.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Middle ear infection: Gently fold in the flap of skin at the front of the ear after you put in the drops. Let go of the flap, then fold it in again. Do this 5 times with a pumping motion. This helps move the medicine through the tube and into the middle ear.

  • Otic routeRemove the cap. Do not let the tip of the dropper touch anything, including your ear.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Otic routeUse this medicine only in your ear.

  • Otic routeKeep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

  • Otic routeYou may warm the drops by holding the unopened bottle in your hands for a few minutes. Cold drops might make you dizzy.

  • Your doctor will tell you how much to use and how often.

  • Wash your hands.

  • Warm the drops by holding the bottle in your hands for a few minutes.

  • Shake the suspension well before using.

  • Never touch the dropper to your ear or anything else.

  • Lie down or tilt your head to the side.

  • Drop the prescribed number of drops into the ear.

  • Keep the ear tilted up for a few minutes or insert a cotton plug into the ear.

  • Wash your hands again so as not to spread the infection.

  • Keep the ear tilted up for a few minutes or insert a cotton plug into the ear.

  • Never touch the dropper to your ear or anything else.

  • Your doctor will tell you how much to use and how often.

  • Wash your hands.

  • Warm the drops by holding the bottle in your hands for a few minutes.

  • Wash your hands again so as not to spread the infection.

  • Lie down or tilt your head to the side.

  • Drop the prescribed number of drops into the ear.

  • Shake the suspension well before using.

What to do if you miss a dose of Ciprodex

  • Use as soon as possible except when it is close to the time for your next dose.

  • If almost time for next dose, skip the missed dose and return to your regular dosing schedule.

  • You should not use two doses at the same time.

Ciprodex contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to ciprofloxacin, dexamethasone, or similar medicines, or if you have an ear infection caused by a fungus or virus (including herpes simplex).

  • Tell your doctor if you are allergic to any antibiotic medicines or to steroids such as cortisone, hydrocortisone, or prednisone.

Ciprodex warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Make sure your doctor knows if you have a history of ear problems or a perforated ear drum.

  • If you have herpes simplex or chicken pox, talk to your doctor before using this medicine.

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.

  • If your symptoms do not get better in one week or become worse, call your doctor.

Ciprodex interactions

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.

  • Make sure your doctor knows if you have a history of ear problems or a perforated ear drum.

  • If you have herpes simplex or chicken pox, talk to your doctor before using this medicine.

  • If your symptoms do not get better in one week or become worse, call your doctor.

  • Tell your doctor if you are pregnant or breastfeeding.

  • If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Ciprodex side effects

Serious Side Effects

  • Skin rash, redness, swelling or intense itching that develops after you start using this medicine.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Stinging or burning of the ear