Lyllana Coupons & Prices

Estradiol

Lyllana is a Estrogens class drug made by Amneal Pharmaceuticals. The average out-of-pocket price of Lyllana is $210.28 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box, but you can pay just $43.88 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box of generic Lyllana when you use a SingleCare prescription drug discount card. Lyllana is a trademark drug; Estradiol is the generic variant of Lyllana.

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1 box1 box (8 twice weekly patches), 0.1mg/24 hrEdit

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Lyllana coupon at CVS Pharmacy
$46.88
$ 43.88
$3 off with signupwith signup

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Lyllana coupon at Walmart Neighborhood Market Pharmacy
$60.44
$ 57.44
$3 off with signupwith signup

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Lyllana coupon at Walmart Pharmacy
$60.44
$ 57.44
$3 off with signupwith signup
Lyllana coupon at Publix Pharmacy
$70.85
$ 67.85
$3 off with signupwith signup
Lyllana coupon at Kroger Pharmacy
$73.02
$ 70.02
$3 off with signupwith signup
Lyllana coupon at Harris Teeter Pharmacy
$73.02
$ 70.02
$3 off with signupwith signup
$ 71.99
$77.33
$ 74.33
$3 off with signupwith signup
$ 79.12

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Lyllana

Lyllana is a Estrogens class drug made by Amneal Pharmaceuticals. The average out-of-pocket price of Lyllana is $210.28 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box, but you can pay just $43.88 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box of generic Lyllana when you use a SingleCare prescription drug discount card. Lyllana is a trademark drug; Estradiol is the generic variant of Lyllana.

Lyllana Price History & Information

Price History for Lyllana (Trademark Generic) & Estradiol (Generic)

1 count, box, 8 patch twice weekly

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Lyllana (Trademark Generic) & Estradiol (Generic)

1 count, box, 8 patch twice weekly
PharmacyLyllana Retail PriceEstradiol Retail PriceEstradiol SingleCare Price
CVS Pharmacy$142.00$108.48$72.72
Walmart$58.24$58.47$52.70
Walgreens$58.80$52.38$45.86
Kroger Pharmacy$172.00$112.20$73.04
Albertsons Pharmacy$195.68$136.12$58.56

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Lyllana

Lyllana is a Estrogens class drug made by Amneal Pharmaceuticals. The average out-of-pocket price of Lyllana is $210.28 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box, but you can pay just $43.88 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box of generic Lyllana when you use a SingleCare prescription drug discount card. Lyllana is a trademark drug; Estradiol is the generic variant of Lyllana.

Lyllana FAQs

How much is Lyllana with SingleCare?

Generic Lyllana costs $43.88 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box with a free Lyllana coupon from SingleCare. However, you could reduce this cost more depending on your Rx details. Use the dropdown menu above to enter your Rx info (i.e., brand/generic, form, dosage, quantity) to find the most accurate price of Lyllana with SingleCare near you.

How much does Lyllana cost without insurance?

The standard cash cost of Lyllana without health insurance is $210.28 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box though you can get a discount using a SingleCare Lyllana coupon to pay only $43.88 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box of generic Lyllana. If you don’t have insurance coverage can still use SingleCare for free Lyllana coupons. You can also reduce your price on Lyllana by asking for the generic form of Lyllana if a generic version is on the market, Estradiol, which often costs much less than Lyllana. 

How much does Lyllana cost with insurance?

Every individual insurance plan is different and may or may not cover Lyllana. The cost of Lyllana with insurance coverage differs depending on your plan - contact your insurance company for specific medication coverage and payment information. If your insurance does not include Lyllana, you can use SingleCare to get discounts on Lyllana at your participating pharmacies. Additionally, you can also use SingleCare discounts if you have Medicare or Medicaid. If Medicare or Medicaid doesn’t provide coverage your Lyllana prescription, use SingleCare instead. Use the SingleCare website or app to compare the lowest price of Lyllana with SingleCare versus your Lyllana price with insurance or Medicare.

How to use SingleCare for Lyllana

SingleCare is accepted at most national pharmacies and grocery stores, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. Simply text, email, print, or save your free Lyllana coupon to your mobile wallet and show a pharmacist at checkout. 

What is the generic of Lyllana?

Lyllana is a trademark drug manufactured by Amneal Pharmaceuticals. The generic variant of Lyllana is Estradiol and is dramatically less expensive than the average price of Lyllana, which is $210.28 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box, but has the same ingredients as Lyllana. Use a SingleCare drug coupon to pay $43.88 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box of generic Lyllana.

Where are Lyllana coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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