What is Ciprofloxacin-Dexamethasone: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 31, 2020

Ciprofloxacin-Dexamethasone overview

BRAND NAMES:

  • Ciprodex

Generic Names:

  • Ciprofloxacin-Dexamethasone

Uses:

  • Treats ear infections caused by bacteria. This medicine contains a quinolone antibiotic and a corticosteroid.

Therapeutic Classes:

  • Antibacterial, Anti-Infective/Anti-Inflammatory Combination

Forms:

  • Liquid, Drop

How it’s taken:

  • Into the ear

What is Ciprofloxacin-Dexamethasone used for?

What form(s) does Ciprofloxacin-Dexamethasone come in

  • Liquid

  • Drop

What are common Ciprofloxacin-Dexamethasone doses?

  • Bottle 7.5ML of 0.3-0.1%

Common Ciprofloxacin-Dexamethasone prescriptions

  • Ciprofloxacin-dexAMETHasone
    7.5ml of 0.3-0.1% bottle

How to take Ciprofloxacin-Dexamethasone

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Otic routeUse this medicine only in your ear.

  • Otic routeYou may warm the drops by holding the unopened bottle in your hands for a few minutes. Cold drops might make you dizzy.

  • Shake the medicine well just before you use it.

  • Otic routeRemove the cap. Do not let the tip of the dropper touch anything, including your ear.

  • Otic routeLie down or tilt your head to the side. For a child, gently pull the child€™s earlobe down and back to straighten the child€™s ear canal. For an adult, gently pull the earlobe up and back to straighten the ear canal.

  • Otic routeDrop the prescribed number of drops into the ear. Keep the ear tilted up for a few minutes or put a cotton ball into your ear.

  • Middle ear infection: Gently fold in the flap of skin at the front of the ear after you put in the drops. Let go of the flap, then fold it in again. Do this 5 times with a pumping motion. This helps move the medicine through the tube and into the middle ear.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Otic routeKeep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

  • Otic routeLie down or tilt your head to the side. For a child, gently pull the child€™s earlobe down and back to straighten the child€™s ear canal. For an adult, gently pull the earlobe up and back to straighten the ear canal.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Shake the medicine well just before you use it.

  • Otic routeDrop the prescribed number of drops into the ear. Keep the ear tilted up for a few minutes or put a cotton ball into your ear.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Middle ear infection: Gently fold in the flap of skin at the front of the ear after you put in the drops. Let go of the flap, then fold it in again. Do this 5 times with a pumping motion. This helps move the medicine through the tube and into the middle ear.

  • Otic routeRemove the cap. Do not let the tip of the dropper touch anything, including your ear.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Otic routeUse this medicine only in your ear.

  • Otic routeKeep the bottle closed when you are not using it. Store it at room temperature, away from light and heat. Do not freeze.

  • Otic routeYou may warm the drops by holding the unopened bottle in your hands for a few minutes. Cold drops might make you dizzy.

What to do if you miss a dose of Ciprofloxacin-Dexamethasone

Ciprofloxacin-Dexamethasone contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to ciprofloxacin, dexamethasone, or similar medicines, or if you have an ear infection caused by a fungus or virus (including herpes simplex).

Ciprofloxacin-Dexamethasone warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Ciprofloxacin-Dexamethasone interactions

  • Tell your doctor if you are pregnant or breastfeeding.

  • If you have ear drainage 2 or more times within 6 months after you stop using the drops, tell your doctor.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Ciprofloxacin-Dexamethasone side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

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