What is Clinolipid? Uses, warnings & side effects

Updated May 14, 2025  •  Published Sep 15, 2022

Clinolipid overview

BRAND NAMES:

  • Smoflipid, Intralipid, Omegaven, Nutrilipid, Clinolipid, Perikabiven, Kabiven

Generic Names:

  • Clinolipid

Uses:

  • Provides calories and essential fatty acids needed by your body. May be given with TPN (total parenteral nutrition)., Provides your body with nutrients such as fat (lipids) and sometimes protein, sugar, vitamins, and minerals. This medicine is needed when you cannot eat food by mouth or if you cannot get enough nutrition from your diet for several days. You may need this medicine if you have serious medical problems such as AIDS, cancer, or serious burns.

Therapeutic Classes:

  • Antidote, Parenteral Lipids

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Clinolipid used for?

What form(s) does Clinolipid come in?

  • Injectable

What are common Clinolipid dosages?

  • Flex Cont 100ml of 20%

How to take Clinolipid

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Clinolipid®: Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • If you receive this medicine at home, a caregiver will teach you, a family member, or friend how to give the medicine. You may need to add vitamins or medicine to the solution before using it. Your caregiver will show you how to do this.

  • Do not use this medicine if the solution (liquid) looks cloudy or has solid pieces floating in it. Do not use the medicine if it is separated like oil and water or is leaking from the bag. Carefully follow all instructions for preparing and giving this medicine.

What to do if you miss a dose of Clinolipid

  • You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Remove the medicine from the refrigerator at least 2 hours before using it. This will bring the solution to room temperature and make the injection more comfortable for you. Do not heat the medicine in a microwave oven.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets. Follow any special instructions about how to throw away empty medicine bottles, tubes, or bags.

  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Clinolipid contraindications - Who shouldn't take Clinolipid?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to egg, fish, or soybean proteins, olive oil, or safflower oil, or if you have a severe bleeding disorder or high cholesterol or triglycerides in the blood.

  • Parenteral solution provides nutrients that your body needs. Unless your doctor tells you otherwise, there is no reason why you should not receive this medicine.

Clinolipid warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, blood clotting problems, heart failure, diabetes, or obesity.

  • This medicine may cause the following problems:Lung or heart problems (including pleural or pericardial effusion), which may be life-threateningIncreased risk of infectionsFat overload syndromeRefeeding syndrome (in severely undernourished patients)Parenteral nutrition-associated liver disease (PNALD)

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Swelling

  • Unusual bleeding, bruising, or weakness

  • Yellow skin or eyes.

  • Swelling in your hands, ankles, or feet.

  • Make sure your doctor knows if you are pregnant or breast feeding. Your nutritional needs may be higher than normal.

  • Tell your doctor if you have diabetes, blood clotting problems, or high cholesterol. Also tell your doctor if you have ever had an allergic reaction to vitamins, eggs, oils, or peanuts.

  • Make sure your doctor knows if you have medical problems with your pancreas, liver, or kidney, or if you have heart disease.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Clinolipid interactions & what to avoid when taking Clinolipid

  • Some medicines can affect how fat emulsion works. Tell your doctor if you are using a blood thinner (including warfarin) or oral omega-3 fatty acid.

  • This medicine may cause the following problems:Fat overload syndromeRefeeding syndromeParenteral nutrition-associated liver disease (PNALD)

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Do not use any other vitamins or mineral supplements without asking your doctor first.

  • Tell your doctor if you have diabetes, blood clotting problems, or high cholesterol. Also tell your doctor if you have ever had an allergic reaction to vitamins, eggs, oils, or peanuts.

  • Make sure your doctor knows if you have medical problems with your pancreas, liver, or kidney, or if you have heart disease.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Clinolipid side effects - How does Clinolipid make you feel?

Serious Side Effects

  • Chest pain, trouble breathing, coughing up blood, cold sweat, bluish-colored skin

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate, difficult or painful urination

  • Fever, chills, cough, sore throat, body aches

  • Unusual bleeding, bruising, or weakness

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Yellow skin or eyes.

  • Rapid weight gain.

  • Swelling in your hands, ankles, or feet.

  • Pale, hot, dry skin with fruit-like breath odor, fainting, and shortness of breath.

  • Numbness or tingling in your hands, feet, or lips.

  • Confusion and weakness with uneven heartbeat and shortness of breath.

  • Confusion and weakness with muscle twitching.

Less Serious Side Effects

  • Redness, pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Dry mouth, increased thirst, muscle cramps, nausea or vomiting.

  • Increase in how much or how often you urinate.

  • Blurred vision, drowsiness, dry mouth, increased thirst.

  • Pain, redness, swelling, or cold feeling where the needle is placed.

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