Cuprimine Coupons & Prices

Penicillamine

Cuprimine (penicillamine) is a brand-name prescription drug that helps remove copper from the body in patients with Wilson's disease, a condition where excess copper accumulates in the body. Cuprimine is also used to treat cystinuria by preventing kidney stone formation. Cuprimine also is sometimes used to reduce swelling in severe cases of rheumatoid arthritis for patients who have not succeeded with other treatments. On average, the retail price of Cuprimine is $37,713.89 but you will pay our lowest price of $1,660.64 with a free SingleCare Cuprimine coupon.

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Cuprimine coupon at Food Lion Pharmacy
$ 1,661

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Cuprimine coupon at Costco Pharmacy
$ 1,861

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Cuprimine coupon at Walgreens Pharmacy
$10862.88
$ 10,860
$3 off with signupwith signup
Cuprimine coupon at Publix Pharmacy
$16637.94
$ 16,635
$3 off with signupwith signup
Cuprimine coupon at Kroger Pharmacy
$18440.78
$ 18,438
$3 off with signupwith signup
Cuprimine coupon at Harris Teeter Pharmacy
$18440.78
$ 18,438
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Cuprimine

Cuprimine (penicillamine) is a brand-name prescription drug that helps remove copper from the body in patients with Wilson's disease, a condition where excess copper accumulates in the body. Cuprimine is also used to treat cystinuria by preventing kidney stone formation. Cuprimine also is sometimes used to reduce swelling in severe cases of rheumatoid arthritis for patients who have not succeeded with other treatments. On average, the retail price of Cuprimine is $37,713.89 but you will pay our lowest price of $1,660.64 with a free SingleCare Cuprimine coupon.

About Cuprimine

Cuprimine (penicillamine) is a brand-name prescription drug that helps remove copper from the body in patients with Wilson's disease, a condition where excess copper accumulates in the body. Cuprimine is also used to treat cystinuria by preventing kidney stone formation. Cuprimine also is sometimes used to reduce swelling in severe cases of rheumatoid arthritis for patients who have not succeeded with other treatments. On average, the retail price of Cuprimine is $37,713.89 but you will pay our lowest price of $1,660.64 with a free SingleCare Cuprimine coupon.

Cuprimine FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Cuprimine cost without insurance?

Patients can usually expect to pay $37,713.89 for 120, 250mg capsules of Cuprimine. Compare this cash price to a SingleCare Cuprimine coupon, $1,660.64 per 120, 250mg capsules. From generics to brand name prescription drugs, you can save as much as 80% with SingleCare prescription discount cards at participating pharmacies.

How much does Cuprimine cost with insurance?

The amount of your Cuprimine copay depends on your insurance plan. With SingleCare, Cuprimine costs as little as $1,660.64 for 120, 250mg capsules, which may be lower than your insurance copay. Ask your pharmacist to do a price comparison. You may save more money with SingleCare than with insurance.

Does Medicare cover Cuprimine and how much does it cost?

Cuprimine is sometimes covered by Medicare Part D and Medicare Advantage prescription drug plans. Patients who do not have coverage can save with a SingleCare Cuprimine coupon and pay $1,660.64 for their prescription.

Is there a generic of Cuprimine?

Cuprimine is a brand-name prescription drug with the active ingredient, penicillamine. Penicillamine is available as a generic from manufacturers such as Oceanside, Teva, and Amerigen. Search for generic penicillamine on the SingleCare website or app for more information and valuable savings coupons.

What is Cuprimine?

Cuprimine is a brand-name prescription drug that helps remove excess copper from the body in patients with Wilson's disease. It can also prevent kidney stone formation in patients with cystinuria. Cuprimine also is sometimes used to reduce swelling caused by severe cases of rheumatoid arthritis for patients who have not succeeded with other treatments.

Cuprimine is usually prescribed to patients with Wilson's disease to help lower the levels of copper in the body. Wilson's disease is a potentially life-threatening genetic disorder that causes copper to accumulate. As copper builds up, it threatens the health of the liver, brain, and other organs. The active ingredient in Cuprimine, penicillamine, attaches to heavy metals like copper and is then excreted with the copper from the body.

Cuprimine also treats cystinuria by binding to cystine (which makes kidney stones) and preventing it from accumulating and from forming kidney stones.

Before taking Cuprimine, tell your doctor about all of your medical conditions and medical history. Be sure to mention if you have kidney or liver disease, a stomach ulcer, a weakened immune system, or if you are malnourished. Tell your doctor if you are allergic to penicillin. Also, tell your doctor about all the medications you take, including prescription and OTC drugs, vitamins, and supplements.

Cuprimine is taken as a capsule on an empty stomach, at least one hour before or two hours after a meal. Avoid milk 1 hour before and 1 hour after taking Cuprimine. Drink plenty of fluids while taking Cuprimine. Ask your doctor if you should take vitamin B6 when you take Cuprimine. If you have Wilson’s disease, your doctor may give you special dietary instructions to follow. 

What are the side effects of Cuprimine?

Side effects are often experienced when taking Cuprimine, and some may be serious or life-threatening. Patients taking Cuprimine are monitored closely by their physician.

Common side effects of Cuprimine include upset stomach, nausea, vomiting, diarrhea, changes in taste, appetite loss, mouth sores, itching/rash, fever, joint pain, and changes in vision.

Serious side effects include low blood cell and low platelet counts that have on rare occasions resulted in patient death.

Allergic reactions are possible and may be serious, such as a lupus-like reaction. Look for rash, itching, blistering and peeling skin, difficulty breathing, swelling around the face and mouth, or fever, and immediately seek emergency medical attention if you suspect an allergic reaction.

This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions. You can report negative side effects to the FDA.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Cuprimine coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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