What is Cyclopentolate: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Cyclopentolate overview

BRAND NAMES:

  • Cyclogyl

Generic Names:

  • Cyclopentolate Hcl

Uses:

  • Used to dilate your eyes before an eye exam.

Therapeutic Classes:

  • Mydriatic-Cycloplegic

Forms:

  • Drop, Liquid

How it’s taken:

  • Into the eye

What is Cyclopentolate used for?

Cyclogyl comes in liquid form and is applied as a drop. It is used before an eye exam and works by relaxing the eye muscles thereby allowing your pupils to dilate. Cyclogyl is usually given about 40 to 50 minutes before an eye exam. Common side effects include blurred vision, mild eye irritation or puffy eyes.

What form(s) does Cyclopentolate come in

  • Drop

  • Liquid

What are common Cyclopentolate doses?

  • Bottle 15ML of 0.5%

  • Bottle 2ML of 1%

  • Bottle 15ML of 1%

  • Bottle 2ML of 2%

  • Bottle 5ML of 2%

  • Bottle 15ML of 2%

Common Cyclopentolate prescriptions

  • Cyclopentolate HCl
    15ml of 0.5% bottle

  • Cyclopentolate HCl
    15ml of 1% bottle

  • Cyclopentolate HCl
    15ml of 2% bottle

  • Cyclopentolate HCl
    2ml of 1% bottle

  • Cyclopentolate HCl
    2ml of 2% bottle

  • Cyclopentolate HCl
    5ml of 2% bottle

How to take Cyclopentolate

  • Use this medicine as directed.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • Ophthalmic routeShake the eye drops well just before each use.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine at room temperature, away from heat and direct light.

  • Your eyes should be dilated within 30 to 60 minutes after you use the medicine.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • Ophthalmic routeShake the eye drops well just before each use.

  • Your eyes should be dilated within 30 to 60 minutes after you use the medicine.

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Use this medicine as directed.

  • Store the medicine at room temperature, away from heat and direct light.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

What to do if you miss a dose of Cyclopentolate

Cyclopentolate contraindications

  • This medicine is not right for everyone. You should not use it if you had an allergic reaction to cyclopentolate, or if you have narrow-angle glaucoma.

Cyclopentolate warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine will make your vision blurry. Your vision should be normal within 6 to 24 hours, but you may have trouble focusing for a few days. Do not drive or do anything else that could be dangerous if you cannot see well.

  • This medicine will make your eyes sensitive to light. Wear sunglasses when you go outside.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have digestion problems, heart disease, nerve or muscle problems, or trouble urinating. If this medicine is being given to a child, tell the doctor if the child has Down syndrome, brain damage, or spastic paralysis.

  • It is best to not feed a baby for 4 hours after the baby receives this medicine.

Cyclopentolate interactions

  • Some medicines can affect how cyclopentolate works. Tell your doctor if you are also using any medicine for glaucoma or other eye problems.

  • This medicine will make your vision blurry. Your vision should be normal within 6 to 24 hours, but you may have trouble focusing for a few days. Do not drive or do anything else that could be dangerous if you cannot see well.

  • This medicine will make your eyes sensitive to light. Wear sunglasses when you go outside.

  • It is best to not feed a baby for 4 hours after the baby receives this medicine.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Cyclopentolate side effects

Serious Side Effects

  • Eye redness, pain, itching, or swelling

  • Eye burning or watering that does not go away

  • Dizziness, trouble walking, unsteadiness

  • Fast heartbeat

  • Unusual behavior, confusion, nervousness

Less Serious Side Effects

  • Dry mouth

  • Mild burning feeling in your eyes right after you use the drops

  • Warmth or redness in your face, neck, arms or upper chest

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