Cytomel is an FDA-approved, synthetic thyroid hormone medication used to treat hypothyroidism, or low thyroid hormone levels. This medication can also be used to treat thyroid cancer. It is a form of hormone replacement therapy that provides the body with T3 hormone, a hormone involved with metabolism, heart rate, and body temperature regulation. The generic version of Cytomel is liothyronine. The average retail price for your Cytomel prescription or refill could be around $183.32 for 90, 5mcg tablets. However, you could use a SingleCare Cytomel coupon and pay a discounted cost of $21.63 for 90, 5mcg tablets of generic Cytomel at local pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Cytomel is an FDA-approved, synthetic thyroid hormone medication used to treat hypothyroidism, or low thyroid hormone levels. This medication can also be used to treat thyroid cancer. It is a form of hormone replacement therapy that provides the body with T3 hormone, a hormone involved with metabolism, heart rate, and body temperature regulation. The generic version of Cytomel is liothyronine. The average retail price for your Cytomel prescription or refill could be around $183.32 for 90, 5mcg tablets. However, you could use a SingleCare Cytomel coupon and pay a discounted cost of $21.63 for 90, 5mcg tablets of generic Cytomel at local pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Cytomel Retail Price | Liothyronine Sodium Retail Price | Liothyronine Sodium SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $51.30 | $98.58 | $78.54 |
| Walmart | $151.20 | $46.35 | $24.45 |
| Walgreens | $218.70 | $56.81 | $38.70 |
| Kroger Pharmacy | $43.20 | $74.24 | $26.74 |
| Albertsons Pharmacy | - | $114.30 | $45.90 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Cytomel is an FDA-approved, synthetic thyroid hormone medication used to treat hypothyroidism, or low thyroid hormone levels. This medication can also be used to treat thyroid cancer. It is a form of hormone replacement therapy that provides the body with T3 hormone, a hormone involved with metabolism, heart rate, and body temperature regulation. The generic version of Cytomel is liothyronine. The average retail price for your Cytomel prescription or refill could be around $183.32 for 90, 5mcg tablets. However, you could use a SingleCare Cytomel coupon and pay a discounted cost of $21.63 for 90, 5mcg tablets of generic Cytomel at local pharmacies.
Without insurance, the average cash price of Cytomel is about $183.32 for 90, 5mcg tablets. You can save on your Cytomel price by using a SingleCare discount coupon for Cytomel. With a Cytomel discount card, you could pay a discounted pricing of $21.63 for 90, 5mcg tablets of generic Cytomel at participating pharmacies, such as CVS Pharmacy, Walmart, Kroger, Walgreens and more.
How much you pay for Cytomel can vary based on your insurance plan. Check with your insurance provider or pharmacist for help determining your copay for Cytomel. With a prescription discount card from SingleCare, you could pay a reduced price of $21.63 for 90, 5mcg tablets of generic Cytomel to refill your Cytomel prescription. SingleCare’s lowest price may be cheaper than the cost with your insurance. You can ask your pharmacist to help you compare prices at your local pharmacy.
The generic version of Cytomel, liothyronine, is usually covered by Medicare prescription drug plans. Check with your insurance plan to determine your exact prescription costs. You could also use a SingleCare prescription savings card to reduce the cost of your Cytomel prescription. Ask your pharmacist to run your SingleCare discount card to compare prices, so you can get the lowest price possible for your Cytomel prescription or refill.
Cytomel is a brand-name prescription medication manufactured by Pfizer. The generic version of this drug is liothyronine.
Cytomel is a synthetic thyroid hormone medication. It is used as a hormone replacement treatment for hypothyroidism, which may be caused after the removal or damage of the thyroid gland. Cytomel can also be used to help manage thyroid cancer, test for thyroid problems, and decrease the size of an enlarged thyroid gland. Cytomel contains a man-made version of the T3 hormone.
Talk to your doctor about any medical conditions you have before taking Cytomel, including diabetes, osteoporosis, heart disease, bleeding problems, adrenal gland problems, or allergies to any thyroid hormone medications. You should also tell your doctor if you are pregnant or breastfeeding before taking Cytomel.
Cytomel is typically prescribed to be taken once daily. The exact dosage will depend on the individual’s medical condition and response to treatment. This drug should only be used as prescribed.
Cytomel may interact with other medications. Do not take Cytomel within 4 hours of taking certain drugs like colesevelam, cholestyramine, colestipol, kayexalate, and sevelamer. Tell your doctor about other medications you may be taking, such as prescription medicines, over-the-counter drugs, and herbal supplements, before starting treatment with Cytomel.
The most common side effects of Cytomel are usually associated with high doses that can lead to hyperthyroidism. These side effects may include headache, irritability, nervousness, insomnia, tremors, increased appetite, weight loss, and diarrhea. Serious side effects may include heart problems, such as arrhythmias and heart attacks, and decreased bone mineral density. Cytomel may also worsen blood sugar levels in those with diabetes. Consult a healthcare provider if you experience any side effects, or if side effects persist or worsen with Cytomel treatment.
This is not a complete list of all side effects that can occur when using this medication. Talk to your doctor or healthcare professional for additional medical advice about other possible side effects, drug interactions, warnings, and precautions before using Cytomel.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved