What is Desmopressin Acetate Spray: Uses, Warnings & Interactions

How to take Desmopressin Acetate Spray

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils.

• DDAVP® or desmopressin generic: Prime the spray bottle the first time you use it by spraying 4 times into the air, away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 50 sprays.

• DDAVP® Rhinal Tube System: This is a soft plastic tube with numbers (doses) marked on the side. Draw the drops into the tube until the liquid reaches the number for your dose. Put one end of the tube into your nose and the other end into your mouth. Blow gently until the medicine is sprayed into your nose. Do not let any medicine run down through the tube into your mouth.

• Noctiva„¢: Prime the spray bottle the first time by spraying 5 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 2 sprays if you do not use the bottle for more than 3 days.Throw away the bottle and any unused medicine 60 days after opening.

• Stimate®: Prime the spray bottle the first time by spraying 4 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 25 sprays.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Noctiva„¢: If you miss a dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

• DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.

• DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.

• Stimate®: Prime the spray bottle the first time by spraying 4 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 25 sprays.

• DDAVP® or desmopressin generic: Prime the spray bottle the first time you use it by spraying 4 times into the air, away from your face. Prime it again with 1 spray if you do not use the bottle for more than 7 days.Throw away the bottle and any unused medicine after 50 sprays.

• DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Noctiva„¢: If you miss a dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

• Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

• DDAVP® Rhinal Tube System: This is a soft plastic tube with numbers (doses) marked on the side. Draw the drops into the tube until the liquid reaches the number for your dose. Put one end of the tube into your nose and the other end into your mouth. Blow gently until the medicine is sprayed into your nose. Do not let any medicine run down through the tube into your mouth.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Noctiva„¢: Prime the spray bottle the first time by spraying 5 times into the air or until you see a fine mist. Spray away from your face. Prime it again with 2 sprays if you do not use the bottle for more than 3 days.Throw away the bottle and any unused medicine 60 days after opening.

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Nasal routeBefore using the medicine, gently blow your nose to clear the nostrils.

• DDAVP®: Store at room temperature in an upright position.Desmopressin generic or DDAVP® Rhinal Tube System: Store in the refrigerator in an upright position. If you will be traveling, the product is good for up to 3 weeks at room temperature.Stimate®: Store at room temperature in an upright position. Throw the bottle away 6 months after it is used for the first time.Noctiva„¢: Keep the unopened nasal spray bottle in the refrigerator in an upright position. You may store the opened bottle at room temperature.

What to do if you miss a dose of Desmopressin Acetate Spray

Desmopressin Acetate Spray contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to desmopressin. Do not use Noctiva„¢ if you are thirsty most of the time and drink large amounts of fluids, wet the bed while sleeping at night, or have a condition called syndrome of inappropriate antidiuretic hormone.

Desmopressin Acetate Spray warnings

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, cystic fibrosis, a nose injury or infection, head injury, or trouble urinating. Tell your doctor about all heart, circulation, or blood problems you have, including heart failure, high blood pressure, or a history of blood clots, heart attack, or stroke.

• This medicine may cause the following problems:Fluid retention (swelling)High blood pressureBlood clotting problems

• Your doctor may limit the amount of fluid or water you drink each day, because this medicine will affect how your body stores water.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. For patients with nocturnal polyuria: Your doctor will need to measure your urine and the times that you urinate for 24 hours.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Severe headache that does not go away

Desmopressin Acetate Spray interactions

• Do not use Noctiva„¢ together with certain diuretic (water pill, including furosemide, torsemide) or systemic or inhaled glucocorticoids (including dexamethasone, fluticasone, methylprednisolone, prednisolone, prednisone).

• Some medicines can affect how desmopressin works. Tell your doctor if you are using any of the following:Carbamazepine, chlorpromazine, hydrochlorothiazide, lamotrigineBlood pressure medicineMedicine to treat anxietyMedicine to treat depression (including SSRIs, TCAs)Medicine to treat an overactive bladderNarcotic pain relieverNSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen).

• Your doctor may limit the amount of fluid or water you drink each day, because this medicine will affect how your body stores water.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.