What is Diazoxide: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Diazoxide overview

BRAND NAMES:

  • Proglycem

Generic Names:

  • Diazoxide

Uses:

  • Treats low blood sugar that is caused by excess insulin.

Therapeutic Classes:

  • Gastrointestinal Agent, Glucose Regulation, Antihypoglycemic

Forms:

  • Capsule, Suspension

How it’s taken:

  • By mouth

What is Diazoxide used for?

What form(s) does Diazoxide come in

  • Capsule

  • Suspension

What are common Diazoxide doses?

  • Bottle 30ML of 50MG/ML

Common Diazoxide prescriptions

  • Diazoxide
    30ml of 50mg/ml bottle

How to take Diazoxide

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take this medicine at the same time each day.

  • Capsule: Swallow whole. Do not crush, break, or chew it.

  • Oral liquid: Shake well just before each use. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze the oral liquid.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Oral liquid: Shake well just before each use. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Take this medicine at the same time each day.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze the oral liquid.

  • Capsule: Swallow whole. Do not crush, break, or chew it.

What to do if you miss a dose of Diazoxide

Diazoxide contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to diazoxide.

Diazoxide warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart failure, edema, lung or breathing problems, or a history of gout.

  • This medicine may cause ketoacidosis (high levels of ketones in the blood) or severe high blood sugar levels and dehydration, which could lead to coma. You will need to test yourself for ketones and sugar levels.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Trouble breathing, especially in a child

Diazoxide interactions

  • Some foods and medicines can affect how diazoxide works. Tell your doctor if you are using any of the following:PhenytoinBlood pressure medicineBlood thinner (including warfarin)Diuretic (water pill), especially a thiazide

  • This medicine may cause ketoacidosis (high levels of ketones in the blood) or severe high blood sugar levels and dehydration, which could lead to coma. You will need to test yourself for ketones and sugar levels.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Diazoxide side effects

Serious Side Effects

  • Lightheadedness, dizziness, or fainting

  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fast, pounding, or uneven heartbeat

  • Increased hunger or thirst, increase in how much or how often you urinate

  • Trouble breathing, especially in a child

Less Serious Side Effects

  • Unusual hair growth on the face, arms, legs, or back

  • Nausea, vomiting, diarrhea

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