What is Doxercalciferol: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Doxercalciferol overview

BRAND NAMES:

  • Hectorol

Generic Names:

  • Doxercalciferol

Uses:

  • Lowers high levels of parathyroid hormone in the body in kidney dialysis patients. Doxercalciferol is a form of vitamin D.

Therapeutic Classes:

  • Calcium Regulator, Endocrine-Metabolic Agent, Nutriceutical, Nutritive Agent

Forms:

  • Capsule, Liquid Filled Capsule

How it’s taken:

  • By mouth

What is Doxercalciferol used for?

Doxercalciferol is used to treat patients with kidney disease who are on dialysis. It is also used to treat secondary hyperparathyroidism. These conditions are associated with higher than normal levels of parathyroid hormone in the body. Doxercalciferol is a form of vitamin D that decreases the level of (PH) and increases the level of calcium and phosphorus in the body. It is indicated for use in adults and is available as a capsule.

What form(s) does Doxercalciferol come in

  • Capsule

  • Liquid Filled Capsule

What are common Doxercalciferol doses?

  • Capsule 0.5MCG

  • Capsule 1MCG

  • Capsule 2.5MCG

Common Doxercalciferol prescriptions

  • Doxercalciferol
    2ml of 4mcg/2ml ampule

  • Doxercalciferol
    0.5mcg capsule

  • Doxercalciferol
    1mcg capsule

  • Doxercalciferol
    2.5mcg capsule

  • Doxercalciferol
    2ml of 4mcg/2ml vial

How to take Doxercalciferol

  • Your doctor will tell you how much to use and how often. You will usually use this medicine at the time you have dialysis.

  • Your doctor will tell you how much to use and how often. You will usually use this medicine at the time you have dialysis.

What to do if you miss a dose of Doxercalciferol

  • This medicine must be used on a regular schedule. If you miss a dose, call your doctor or dialysis unit for instructions.

  • Keep all medicine away from children.

Doxercalciferol contraindications

  • You should not use this medicine if you have had an allergic reaction to doxercalciferol or vitamin D, or if you have recently had high blood calcium levels.

Doxercalciferol warnings

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.

  • Make sure your doctor knows if you have liver disease or if you have a history of high levels of phosphate or calcium in your blood.

  • Irregular heartbeat

  • Loss of appetite, weight loss

  • Nausea, vomiting, constipation

  • Unusual weakness, tiredness

  • Unexplained headache

Doxercalciferol interactions

  • Follow the diet plan your doctor gives to you.

  • Avoid antacids that contain magnesium (such as Maalox® and Mylanta®) while using this medicine.

  • Make sure your doctor knows if you are using cholestyramine (Questran®), mineral oil, phenobarbital (Donnatal®), phenytoin (Dilantin®), glutethimide (Doriden®), or digitalis drugs such as digoxin (Lanoxin®) or digitoxin (Crystodigin®).

  • Do not use calcium supplements or any other type of vitamin D without first asking your doctor.

Doxercalciferol side effects

Serious Side Effects

  • Unusual weakness, tiredness

  • Nausea, vomiting, constipation

  • Bone or muscle pain

  • Dry mouth, metallic taste in mouth

  • Irregular heartbeat

  • Unexplained headache

  • Loss of appetite, weight loss

Less Serious Side Effects

  • Difficult breathing

  • Weight gain

  • Swelling of the hands or feet

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