What is Evotaz: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Evotaz overview

BRAND NAMES:

  • Evotaz

Generic Names:

  • Evotaz

Uses:

  • Treats HIV infection. HIV causes AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.

Therapeutic Classes:

  • Antiretroviral Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Evotaz used for?

Evotaz is an antiviral medication. It is used together with other antiretrovirals to treat patients with HIV-1 infections. It contains atazanavir and cobicistat. They work together to reduce the viral load in the body. Evotaz is indicated for use in adults and is available as a tablet.

What form(s) does Evotaz come in

  • Tablet

What are common Evotaz doses?

  • Tablet 300-150MG

Common Evotaz prescriptions

  • Evotaz
    30 tablets bottle

  • Evotaz
    300-150mg tablet

How to take Evotaz

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral routeIt is best to take this medicine with food or milk.

  • Contact your doctor or pharmacist when your supply of this medicine is low. Do not allow yourself to run out of this medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Oral routeIt is best to take this medicine with food or milk.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Contact your doctor or pharmacist when your supply of this medicine is low. Do not allow yourself to run out of this medicine.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Evotaz

Evotaz contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to atazanavir or cobicistat, or if you are pregnant.

Evotaz warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Use another form of birth control (including condoms or spermicide) along with your pills.

  • Tell your doctor if you are pregnant, or if you have kidney disease, liver disease, diabetes, heart rhythm problems, or bleeding problems (including hemophilia).

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Heart rhythm problemsSerious skin reactionsKidney problems, including chronic kidney disease or Fanconi syndrome (when used together with tenofovir DF)Kidney stones or gallstonesLiver problemsHigh blood sugarIncreased risk of bleedingLactic acidosis (too much acid in the blood) in pregnant women

  • Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Do not stop using this medicine unless your doctor tells you to. If you stop the medicine even for a short time, the virus may become harder to treat.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Evotaz interactions

  • You must avoid many other medicines while you are using cobicistat with atazanavir. These medicines used together could cause serious health problems, including death. Medicines you must avoid include the following: alfuzosin, carbamazepine, cisapride, dronedarone, drospirenone/ethinyl estradiol, elbasvir/grazoprevir, glecaprevir/pibrentasvir, indinavir, irinotecan, lomitapide, lovastatin, lurasidone, midazolam, nevirapine, phenobarbital, phenytoin, pimozide, ranolazine, rifampin, sildenafil for pulmonary hypertension, simvastatin, St John's wort, triazolam, and ergot medicines (including dihydroergotamine, ergotamine, methylergonovine). Do not use this medicine together with colchicine if you have kidney or liver disease.

  • There are many other drugs that can interact with this medicine. Ask your doctor before you use any other medicine.

  • If you use antacids, take them 2 hours before or 2 hours after you take this medicine.

  • Take this medicine at least 2 hours before or 1 hour after taking didanosine

  • Do not stop using this medicine unless your doctor tells you to. If you stop the medicine even for a short time, the virus may become harder to treat.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Evotaz side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Unusual bleeding, bruising, or weakness

  • Blistering, peeling, red skin rash

  • Fast, pounding, or uneven heartbeat, dizziness or lightheadedness

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Change in how much or how often you urinate, red or pink urine, lower back or side pain

Less Serious Side Effects

  • Weight gain around your neck, upper back, breast, face, or waist