Tresiba is a type of insulin with the active ingredient insulin degludec. The pharmaceutical company that makes this brand-name drug is called Novo Nordisk. Tresiba is used to control blood sugar in patients with diabetes. Tresiba is known as a basal (or “background”) insulin. It is used once daily to control fasting blood sugar levels. Tresiba costs $478.80 for 1, 10ml of 100unit/ml vial, but a Tresiba coupon from the SingleCare discount program can significantly reduce your out-of-pocket expense. Take one of the free coupons below to a participating pharmacy to pay $118.02 for 1, 10ml of 100unit/ml vial when you fill a prescription. Note: You'll find different pricing and prescribing information than Tresiba Flextouch pens below. You can search for Tresiba Flextouch on singlecare.com above.
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Los precios de los medicamentos recetados de SingleCare se basan en diversas fuentes. Los precios que publicamos son nuestra mejor estimación, pero no podemos garantizar que el precio que mostramos coincida exactamente con el precio que recibes en la farmacia. Para saber el precio exacto, por favor, comunícate con tu farmacia y proporciona los números BIN/GRP/PCN que aparecen en tu tarjeta de SingleCare.
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Precios actualizados: 05/12/2025
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Tresiba is a type of insulin with the active ingredient insulin degludec. The pharmaceutical company that makes this brand-name drug is called Novo Nordisk. Tresiba is used to control blood sugar in patients with diabetes. Tresiba is known as a basal (or “background”) insulin. It is used once daily to control fasting blood sugar levels. Tresiba costs $478.80 for 1, 10ml of 100unit/ml vial, but a Tresiba coupon from the SingleCare discount program can significantly reduce your out-of-pocket expense. Take one of the free coupons below to a participating pharmacy to pay $118.02 for 1, 10ml of 100unit/ml vial when you fill a prescription. Note: You'll find different pricing and prescribing information than Tresiba Flextouch pens below. You can search for Tresiba Flextouch on singlecare.com above.
Tresiba is a type of insulin with the active ingredient insulin degludec. The pharmaceutical company that makes this brand-name drug is called Novo Nordisk. Tresiba is used to control blood sugar in patients with diabetes. Tresiba is known as a basal (or “background”) insulin. It is used once daily to control fasting blood sugar levels. Tresiba costs $478.80 for 1, 10ml of 100unit/ml vial, but a Tresiba coupon from the SingleCare discount program can significantly reduce your out-of-pocket expense. Take one of the free coupons below to a participating pharmacy to pay $118.02 for 1, 10ml of 100unit/ml vial when you fill a prescription. Note: You'll find different pricing and prescribing information than Tresiba Flextouch pens below. You can search for Tresiba Flextouch on singlecare.com above.
If this is a new prescription for you, you might be surprised to learn that the cash price of Tresiba without insurance is $478.80 for 1, 10ml of 100unit/ml vial on average. Whether your healthcare plan doesn't cover Tresiba or you don't have insurance at all, you can still save money on this brand-name prescription. You'll pay only $118.02 for 1, 10ml of 100unit/ml vial with one of our free coupons for Tresiba.
Tresiba copays vary by insurance plan. You can request an accurate total from your pharmacist. However, your health insurance may not get you maximum savings.
Our lowest price for Tresiba is $118.02 for 1, 10ml of 100unit/ml vial, which could be lower than your copay. To make sure you're always getting the best deal for your medications, ask your pharmacist to compare your total with insurance versus your discount with your SingleCare savings card, which you can find on our site or mobile app. Anyone in the US with a valid prescription can use SingleCare, and there are no eligibility requirements or personal information or data required.
Tresiba is covered by the majority of healthcare plans including Medicare prescription plans. However, pharmacy discount cards can sometimes offset the cost of prescription medications even more than Medicare. Use the SingleCare website or mobile app to find the local pharmacy with the lowest price and then ask your pharmacist to compare both discounts—one with Medicare coverage and one with our Tresiba coupon. At $118.02 for 1, 10ml of 100unit/ml vial, your SingleCare savings could be greater than your insurance coverage.
Using your SingleCare instant savings card may help to find the cheapest price for Tresiba. Many of our customers have reported that they save more money with our coupons than the manufacturer's rebates. The lowest discounted price we offer for Tresiba is currently $118.02 for 1, 10ml of 100unit/ml vial.
Tresiba is a brand name for insulin degludec. A generic substitute has not been released by the FDA in the United States. Generic drugs are usually more affordable than brand-name drugs. Until a cheaper generic alternative of Tresiba is available, you can pay just $118.02 for 1, 10ml of 100unit/ml vial per prescription fill with your SingleCare card. Compare this more affordable price to the retail price of Tresiba, which is $478.80 for 1, 10ml of 100unit/ml vial.
Tresiba is an insulin that helps control blood sugar. By maintaining balanced blood sugar levels, Tresiba can also help patients with diabetes from suffering long-term complications like loss of vision or limbs, nerve damage, kidney problems, and sexual dysfunction, as well as heart attack or stroke. Although Tresiba may be prescribed to individuals with Type 1 diabetes or Type 2 diabetes, it should not be used in patients with diabetic ketoacidosis.
Tresiba is available in a 10 mL of 100 unit/mL vial. It may be injected under the skin in the stomach, thighs, or upper arms, but you should rotate injection sites to prevent irritation and to avoid skin problems such as lipodystrophy.
Each insulin dose provides a low, steady amount of insulin. Tresiba lasts longer than regular insulin so it may be used with shorter-acting insulin (but not in the same syringe) and other diabetes medications. Ask your doctor or pharmacist for more important safety information.
If this formulation doesn't work for your lifestyle or insulin needs, you may also ask your health care provider about trying a 30-day supply of Tresiba Flexpens.
Tresiba should never be mixed or diluted with other insulin products, and if you are using the Flexpen, you should not transfer Tresiba from the pen into a syringe. Tresiba is also not for use in an insulin pump.
Although Tresiba should not be mixed or diluted with other insulin in a syringe, oftentimes people do use several types of insulin, just not in the same syringe. For example, you may take a once-daily dose of Tresiba, and then you may also have a different, fast-acting form of insulin (such as Novolog or Humalog) that you inject before meals. People who use more than one insulin must always double-check that they are injecting the correct dose of the correct insulin.
Low blood sugar (hypoglycemia), upper respiratory infections, sinus infections, headache, diarrhea, weight gain, and swelling of the arms or legs are common side effects. Injection site reactions may also occur.
Disclose your medical history (particularly one of kidney and liver disease) and a full list of medicines to avoid life-threatening side effects and drug interactions from occurring.
Other side effects, including serious side effects, can occur. Serious allergic reactions may occur. If you have symptoms of hives, shortness of breath, or swelling of the face, lips, tongue, or throat, get emergency medical help right away.
Before taking Tresiba, read the patient information leaflet. Ask your pharmacist for a full list of possible side effects.
Before using Tresiba, tell your physician about all the other drugs you take, including Rx and over-the-counter medicines, vitamins, and supplements.
Certain drugs, when combined with Tresiba, may increase the risk of low blood sugar, or hypoglycemia. Examples include:
Other diabetes medicines
ACE inhibitors such as Altace (ramipril)
ARBs such as Cozaar (losartan)
Tricor (fenofibrate)
MAOI antidepressants such as phenelzine or selegiline
Sulfa antibiotics such as Bactrim
Other drugs, when combined with Tresiba, may interfere with Tresiba’s ability to lower blood sugar. Examples include:
Corticosteroids such as prednisone
Estrogens
Oral contraceptives (birth control pills)
Niacin
Diuretics such as hydrochlorothiazide or Lasix (furosemide)
Thyroid medication
Antipsychotics
Some drugs may have an unpredictable effect, and can either increase or decrease the ability of Tresiba to lower blood sugar. Examples include:
Alcohol
Lithium
Beta-blockers such as Tenormin (atenolol) or Toprol XL (metoprolol)
Clonidine
And, some drugs can mask the symptoms of low blood sugar, such as clonidine and beta blockers.
Although interactions may occur, these drugs do not necessarily always need to be avoided, but may require a dosage adjustment and/or closer monitoring of blood sugar. Consult your healthcare provider for additional information, questions, and medical advice.
This is not a full list of drug interactions and others may occur.
Tresiba should not make you feel tired. However, if you take a Type 2 diabetes medication in the thiazolidinedione (TZD) class of drugs such as Actos (pioglitazone), in addition to Tresiba, your risk for heart failure could increase. Symptoms of heart failure include tiredness, trouble breathing, swelling in the ankles and feet, and sudden weight gain.
Tresiba is usually injected once a day at about the same time each day. Your doctor may have a preference of whether you inject Tresiba in the morning, afternoon, or at night. Ask your healthcare professional for specific instructions based on your prescription.
Tresiba should not be taken by people who are allergic to insulin degludec. Tresiba should not be used in an IV (infusion into a vein) or insulin pump. It also should not be used when blood sugar is too low. Your healthcare provider will instruct you on how and when to use Tresiba, especially during times of infection, illness, or stress.
People with kidney or liver problems, or low potassium levels, should consult their healthcare professional before using Tresiba.
Tresiba (insulin degludec), Lantus (insulin glargine), Toujeo (insulin glargine), and Levemir (insulin detemir) are popular basal, or long-acting insulins. Tresiba is currently the longest-acting insulin available.
If you are looking for another option besides Tresiba, talk to your doctor. Your doctor will determine which insulin is the best for your specific medical condition, history, and response to treatment.
Although Lantus and Tresiba are both insulins that control blood sugar, they are chemically different. Compare the differences between the two diabetes medications below.
Lantus:
is a brand name for insulin glargine.
is available in a vial or pen form.
provides blood sugar control over a 24-hour period.
may be administered to adults and children who are at least six years old.
Tresiba:
is a brand name for insulin degludec.
is available in a vial or pen form.
can last up to 42 hours.
may be administered to adults and children who are at least one year old.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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