What is Extraneal? Uses, warnings & side effects

Updated May 14, 2025  •  Published Feb 14, 2024

Extraneal is used as part of a continuous ambulatory peritoneal dialysis. There is not a generic version of Extraneal presently available on the market. The average Extraneal cost is about $101 for a supply of 2000 ml of 7.5% dialysis solution. However, you can significantly reduce the Extraneal price by using our free Singlecare coupon card at participating local pharmacies.

Extraneal overview

BRAND NAMES:

  • Extraneal

Generic Names:

  • Extraneal

Uses:

  • Used as part of a dialysis process for cleaning waste out of your body.

Therapeutic Classes:

  • Dialysis Solution

Forms:

  • Injectable

How it’s taken:

  • Into the abdomen

What is Extraneal used for?

Extraneal belong to the intravenous nutritional products drug class. It is used as part of a continuous ambulatory peritoneal dialysis in the management of kidney disease. Extraneal removes toxic fluids and wastes from the blood. It is indicated for use by adults and is available as an injection.

What form(s) does Extraneal come in?

  • Injectable

What are common Extraneal dosages?

  • Flex Cont 2000ml of 7.5%

How to take Extraneal

  • You may warm the solution up to body temperature with a dry heating pad before you use it. Leave the wrapper on while you heat it. Do not warm the solution in a microwave oven or put it in water. Do not let the solution get above 104 degrees F.

  • Look at the solution in its container before you use it. Do not use the solution if it is cloudy or has small specks floating in it. Do not use it if the container has a leak.

  • Always wash your hands before you handle your catheter or medicine.

  • This solution is for the long dwell exchange of peritoneal dialysis, which lasts longer than 8 hours. Do not use this solution more than 1 time in 24 hours, unless your doctor tells you to. You will have other solutions to use during shorter exchanges.

  • Your caregiver should teach you about peritoneal dialysis and how to use this solution. Make sure you understand all instructions before you do the process yourself. Follow all of the steps in the process exactly as you were trained to do.

  • Your doctor will decide how much of the solution you need and tell you how often it should be used. This solution is given through a catheter that is placed in your abdomen during a minor operation.

  • Injection routeIf you store this medicine at home, keep it at room temperature, away from heat, moisture, and direct light. Do not freeze. Keep the solution in the box and wrapper until you are ready to use it.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Throw away any solution you did not use.

  • Do not add anything to the solution unless your health caregiver tells you to. Other medicines and minerals are sometimes added, but you will be told about this if needed.

  • After you drain the fluid back out of your catheter, look at the fluid. Call your caregiver if it is cloudy or you see clumps or stringy material.

  • If you use too much icodextrin, you might feel full or bloated or have trouble breathing. Your abdomen might look bigger. If this happens, drain out some of the solution.

What to do if you miss a dose of Extraneal

Extraneal contraindications - Who shouldn't take Extraneal?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to icodextrin or cornstarch.

Extraneal warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This solution may cause false high blood sugar readings for some monitors and test strips. You must use only a glucose-specific monitor and test strips. Your doctor should help you choose the right monitor and test strips.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have diabetes or low blood pressure. Tell your doctor if you cannot take maltose or isomaltose, or if you have glycogen storage disease or lactic acidosis.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Tell any doctor who treats you that you are using this medicine, especially if you are in the hospital or emergency room.

  • Keep track of how much fluid you have in your body at all times, because it is easy to have too much or too little. Weigh yourself often, and write the number down.

Extraneal interactions & what to avoid when taking Extraneal

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep track of how much fluid you have in your body at all times, because it is easy to have too much or too little. Weigh yourself often, and write the number down.

  • Tell any doctor who treats you that you are using this medicine, especially if you are in the hospital or emergency room.

  • Some medicines can affect how icodextrin works. Tell your doctor if you are using any of the following:DigoxinInsulinMedicine to treat HIV/AIDS or hepatitis

  • Icodextrin might remove other medicines from your body, so your doctor might need to change your dose of the other medicines. However, do not change any doses unless your doctor tells you to.

Extraneal side effects - How does Extraneal make you feel?

Serious Side Effects

  • Cloudy fluid or clumps in fluid after draining

  • Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion

  • Redness, swelling, or pain where the catheter goes into your abdomen or stomach

  • Blistering, peeling, or red skin rash

  • Fever, chills, cough, sore throat, and body aches

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Nausea, stomach pain

  • Headache

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