What is Fluphenazine Decanoate: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Fluphenazine Decanoate overview

BRAND NAMES:

Generic Names:

  • Fluphenazine Decanoate

Uses:

  • Treats schizophrenia.

Therapeutic Classes:

  • Antipsychotic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Fluphenazine Decanoate used for?

What form(s) does Fluphenazine Decanoate come in

  • Injectable

What are common Fluphenazine Decanoate doses?

  • Vial 5ML of 25MG/ML

  • Bottle 1GM of

Common Fluphenazine Decanoate prescriptions

  • fluPHENAZine Decanoate
    5ml of 25mg/ml vial

How to take Fluphenazine Decanoate

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin or into a muscle.

  • Injection routeA nurse or other health provider will give you this medicine.

  • A single shot of this medicine may last as long as 4 weeks. Make sure you keep all doctor's appointments.

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin or into a muscle.

  • A single shot of this medicine may last as long as 4 weeks. Make sure you keep all doctor's appointments.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Fluphenazine Decanoate

Fluphenazine Decanoate contraindications

  • You should not receive this medicine if you have had an allergic reaction to fluphenazine or a phenothiazine (such as Compazine®, Phenergan®, Thorazine®,or Serentil®). You should not receive this medicine if you have liver disease or a blood disorder, or if you are using large doses of medicines that make you sleepy. This medicine should not be given to a child younger than 12 years old.

Fluphenazine Decanoate warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver disease, kidney disease or pheochromocytoma (tumor of the adrenal gland). Tell your doctor if you have a history of seizures.

  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • Make sure your doctor knows if you are exposed to extreme heat or insecticides.

  • Make sure any doctor who treats you knows that you are using this medicine. This medicine may affect the results of pregnancy tests.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Fever, sweating, confusion, uneven heartbeat, muscle stiffness.

  • Light-headedness or fainting.

  • Nausea, vomiting, loss of appetite, pain in your upper stomach.

  • Problems with balance, walking, or speech.

  • Swelling in your hands, ankles, or feet.

  • Twitching or muscle movements you cannot control (often in your eyes, tongue, arems, legs, jaw, neck or upper body).

  • Unusual bleeding, bruising, or weakness.

  • Yellowing of your skin or the whites of your eyes.

Fluphenazine Decanoate interactions

  • Make sure your doctor knows if you are also using atropine, or pain or arthritis medicine (such as aspirin, ibuprofen, Advil®, Aleve®, Motrin®, Orudis®).

  • Do not drink alcohol while you are using this medicine.

  • Make sure your doctor knows if you are exposed to extreme heat or insecticides.

  • Make sure any doctor who treats you knows that you are using this medicine. This medicine may affect the results of pregnancy tests.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Fluphenazine Decanoate side effects

Serious Side Effects

  • Twitching or muscle movements you cannot control (often in your eyes, tongue, arems, legs, jaw, neck or upper body).

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision or headache.

  • Change in how much or how often you urinate.

  • Dark-colored urine or pale stools.

  • Fast heartbeat.

  • Fever, sweating, confusion, uneven heartbeat, muscle stiffness.

  • Light-headedness or fainting.

  • Nausea, vomiting, loss of appetite, pain in your upper stomach.

  • Problems with balance, walking, or speech.

  • Yellowing of your skin or the whites of your eyes.

  • Swelling in your hands, ankles, or feet.

  • Unusual bleeding, bruising, or weakness.

Less Serious Side Effects

  • Trouble having sex (in men).

  • Dry mouth.

  • Menstrual pain or irregularity.

  • Runny or stuffy nose.

  • Constipation.

  • Loss of appetite or change in your weight.

  • Muscle cramps.

  • Excessive salivation.

  • Mild skin rash or discoloration.