What is Fulphila: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Fulphila overview

BRAND NAMES:

  • Fulphila, Neulasta Onpro, Ziextenzo, Neulasta, Udenyca

Generic Names:

  • Fulphila

Uses:

  • Helps your body make white blood cells after you receive cancer medicine., Helps your body make white blood cells after you receive cancer medicine. Also used to improve survival in people who have been exposed to radiation.

Therapeutic Classes:

  • Hematopoietic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Fulphila used for?

What form(s) does Fulphila come in

  • Injectable

What are common Fulphila doses?

  • Syringe 0.6ml of 6mg/0.6ml

Common Fulphila prescriptions

  • Fulphila
    0.6ml of 6mg/0.6ml syringe

How to take Fulphila

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze. Keep this medicine in its original carton. Throw away any medicine stored at room temperature for more than 72 hours. If frozen, thaw it in the refrigerator before using. Throw away any medicine if it has been frozen more than once.

  • Use the syringe only once. Do not save leftover medicine.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Injection routeUse a new needle and syringe each time you inject your medicine.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Allow this medicine to warm to room temperature for 30 minutes before you use it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Check the liquid in the prefilled syringe. Do not use the medicine if the liquid is cloudy, discolored, or has particles in it. Do not shake.

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Do not inject into skin areas that are tender, red, bruised, hard, or have scars or stretch marks.

  • Start using the medicine 24 hours or more after you finish your chemotherapy. However, do not use it within 24 hours before you begin another chemotherapy treatment.

  • Do not shake the syringe. Use the syringe only once. Do not save leftover medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Neulasta® single-use prefilled syringe: If you store this medicine at home, keep it in the refrigerator. Do not freeze. If the medicine is accidentally frozen, let it thaw out in the refrigerator before you use it. If the medicine freezes a second time, do not use it. Keep the medicine in the carton and away from heat or direct light. The medicine can stay out of the refrigerator for up to 48 hours. Throw away any medicine that has been out of the refrigerator for more than 48 hours.

  • Neulasta® Onpro„¢ kit: Keep the medicine in the carton and away from heat or direct light. The medicine can stay out of the refrigerator for up to 12 hours. Throw away any medicine that has been out of the refrigerator for more than 12 hours.

What to do if you miss a dose of Fulphila

Fulphila contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to pegfilgrastim or filgrastim.

Fulphila warnings

  • This medicine may cause the following problems:Spleen problemsLung problems (including acute respiratory distress syndrome)Kidney problemsCapillary leak syndromeAortitis (swelling of the largest artery in the body)

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, lung disease, breathing problems, or sickle cell disease.

  • Unusual bleeding, bruising, tiredness, or weakness

  • Trouble breathing or fast breathing

  • Swelling in your face, ankles, or feet

  • On-body Injector for Neulasta®: Keep the injector at least 4 inches away from electrical equipment, including cell or cordless phones, microwaves, and other appliances.Do not use hot tubs or saunas while you are wearing the injector. Do not expose the injector to sunlight. Do not sleep on the injector. Call your doctor if the injector comes off before or during a dose.Keep the injector dry at least 3 hours before the dose is scheduled to start. This will help you notice any leaks. Call your doctor if the bandage becomes wet or the medicine is dripping.The injector is programmed to deliver your dose about 27 hours after it is placed on your skin. It will take about 45 minutes for the dose to be given. Avoid activities, including driving and traveling, that may interfere with the injector 1 hour before the dose starts, while it is being given, and for at least 1 hour afterward.

  • This medicine may cause the following problems:Spleen problemsLung problems (including acute respiratory distress syndrome)Kidney problemsCapillary leak syndrome

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, lung disease, breathing problems, or sickle cell disease. Tell your doctor if you have an allergy to acrylic adhesives or latex.

Fulphila interactions

  • Do not use this medicine between 14 days before and 24 hours after receiving cancer medicine.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, lung disease, breathing problems, or sickle cell disease. Tell your doctor if you have an allergy to acrylic adhesives or latex.

  • This medicine may cause the following problems:Spleen problemsSerious lung problemsKidney problemsCapillary leak syndrome

  • On-body Injector for Neulasta®: Keep the injector at least 4 inches away from electrical equipment, such as cell or cordless phones, microwaves, and other appliances.Do not use hot tubs or saunas while you are wearing the injector. Do not expose the injector to sunlight. Do not sleep on the injector. Call your doctor if the injector comes off before or during a dose.Keep the injector dry at least 3 hours before the dose is scheduled to start. This will help you notice any leaks. Call your doctor if the bandage becomes wet or the medicine is dripping.The injector is programmed to deliver your dose about 27 hours after it is placed on your skin. It will take about 45 minutes for the dose to be given. Avoid activities, such as driving and traveling, that may interfere with the injector 1 hour before the dose starts, while it is being given, and for at least 1 hour afterward.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Fulphila side effects

Serious Side Effects

  • Unusual bleeding, bruising, tiredness, or weakness

  • Skin redness, blisters, or sores, red or purple spots on your skin

  • Fever, chills, cough, sore throat, body aches

  • Swelling in your face, ankles, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Lightheadedness, dizziness, or fainting

  • Trouble breathing or fast breathing, chest pain

  • Pain in your left side or shoulder, feeling unusually full, stomach pain

  • Decrease in how much or how often you urinate, red or dark brown urine, lower back or side pain

  • Trouble breathing or fast breathing

  • Pain in your left side or shoulder, or feeling unusually full

Less Serious Side Effects

  • Bone, arm, or leg pain

  • Pain, redness, or swelling where the shot was given

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