What is Ganciclovir Sodium: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Ganciclovir Sodium overview

BRAND NAMES:

  • Cytovene IV

Generic Names:

  • Ganciclovir Sodium

Uses:

  • Treats or prevents infections caused by cytomegalovirus (CMV).

Therapeutic Classes:

  • Antiviral

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Ganciclovir Sodium used for?

Cytovene is an antiviral drug used to treat infections caused by cytomegalovirus. This drug blocks the infection which minimizes the growth and spread of cytomegalovirus. Cytomegalovirus is present in patients who have an organ transplant or have been diagnosed with AIDS.

What form(s) does Ganciclovir Sodium come in

  • Injectable

What are common Ganciclovir Sodium doses?

  • Solution Reconstituted 500MG

  • Vial 10ML of 500MG/10ML

Common Ganciclovir Sodium prescriptions

  • Ganciclovir Sodium
    500mg solution reconstituted

  • Ganciclovir Sodium
    10ml of 500mg/10ml vial

How to take Ganciclovir Sodium

  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Use a new needle and syringe each time you inject your medicine. Never share your medicine with anyone.

  • A nurse or other trained health professional will give you this medicine. It may also be given by a home health caregiver.

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.

  • Use a new needle and syringe each time you inject your medicine. Never share your medicine with anyone.

  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • A nurse or other trained health professional will give you this medicine. It may also be given by a home health caregiver.

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.

What to do if you miss a dose of Ganciclovir Sodium

  • If you miss more than one dose, call your doctor or caregiver for instructions.

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose.

  • Do not use extra medicine to make up for a missed dose.

Ganciclovir Sodium contraindications

  • You should not use this medicine if you have had an allergic reaction to ganciclovir, acyclovir (Zovirax®), famciclovir (Famvir®), or valacyclovir (Valtrex®).

Ganciclovir Sodium warnings

  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • If your symptoms of CMV get worse while you are taking this medicine, contact your doctor.

  • Use two forms of birth control to avoid pregnancy while you are using this medicine and for at least 90 days after your treatment ends. This is very important whether you are a man or a woman.

  • Make sure your doctor knows if you have kidney disease or are on kidney dialysis.

  • Do not breastfeed while you are being treated with this medicine.

  • If you plan to have children, talk with your doctor before using this medicine. Some men and women using this medicine have become infertile (unable to have children).

  • This medicine can cause birth defects if it is used by the mother while she is pregnant or by the father when his sexual partner becomes pregnant. If a pregnancy occurs while you are using this medicine, tell your doctor right away.

  • Ganciclovir does not cure CMV eye infections, but it may keep the infection from getting worse. If you have a CMV eye infection, you will need to have your eyes tested regularly while taking ganciclovir.

Ganciclovir Sodium interactions

  • Use two forms of birth control to avoid pregnancy while you are using this medicine and for at least 90 days after your treatment ends. This is very important whether you are a man or a woman.

  • Make sure your doctor knows if you are also using didanosine (Videx®), zidovudine (Retrovir®), probenecid (Benemid®), imipenem-cilastatin (Primaxin®), dapsone, pentamidine, flucytosine (Ancobon®), amphotericin B, cotrimoxazole (Septra®, Bactrim®), or any medicine to treat cancer.

  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

  • If your symptoms of CMV get worse while you are taking this medicine, contact your doctor.

  • Ganciclovir does not cure CMV eye infections, but it may keep the infection from getting worse. If you have a CMV eye infection, you will need to have your eyes tested regularly while taking ganciclovir.

  • Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

  • If you plan to have children, talk with your doctor before using this medicine. Some men and women using this medicine have become infertile (unable to have children).

  • Do not breastfeed while you are being treated with this medicine.

  • Make sure your doctor knows if you have kidney disease or are on kidney dialysis.

Ganciclovir Sodium side effects

Serious Side Effects

  • Severe skin rash

  • Pain or swelling where the IV is given

  • Confusion, extreme weakness or tiredness

  • Fever, chills, or sore throat, or flu-like symptoms

  • Unusual bleeding or bruising

Less Serious Side Effects

  • Numbness or tingling in your hands or feet

  • Nausea, vomiting, diarrhea, loss of appetite