What is Herceptin: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Herceptin overview

BRAND NAMES:

  • Ontruzant, Trazimera, Herceptin, Herzuma, Kanjinti, Ogivri

Generic Names:

  • Herceptin

Uses:

  • Treats cancer, including breast, stomach, and esophageal cancer.

Therapeutic Classes:

  • Immunological Agent, Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Herceptin used for?

Herceptin is a HER2 inhibitor that is used to treat adjuvant breast cancer, metastatic breast cancer and other conditions as prescribed by your doctor. HER2 (Human Epidermal growth factor Receptor 2) is a gene found in cancer cells that stimulate these cells to grow. Some breast cancer cells overexpress their HER2 gene, this results in rapid, disorderly growth and division of cancer cells causing the cancer to spread and grow. Herceptin blocks the action of the HER2 gene and slows or stops the growth of the breast cancer. Herceptin may be used alone or in combination with other cancer treatment. It is available as an intravenous injection.

What form(s) does Herceptin come in

  • Injectable

What are common Herceptin doses?

  • Solution Reconstituted 150MG

Common Herceptin prescriptions

  • Herceptin
    150mg solution reconstituted

  • Herceptin
    440mg solution reconstituted

How to take Herceptin

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

What to do if you miss a dose of Herceptin

Herceptin contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to trastuzumab, or if you are pregnant.

Herceptin warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control to prevent pregnancy while you receive this medicine and for 7 months after your treatment ends.

  • Tell your doctor if you are breastfeeding, or if you have heart disease, heart rhythm problems, high blood pressure, or lung disease.

  • This medicine may cause the following problems:Heart problemsInfusion-related reactionsLung or breathing problems

  • This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You may also need occasional tests of your heart function during and after treatment.

Herceptin interactions

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. You may also need occasional tests of your heart function during and after treatment.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control to prevent pregnancy while you receive this medicine and for 7 months after your treatment ends.

  • Tell your doctor if you are breastfeeding, or if you have heart disease, heart rhythm problems, high blood pressure, or lung disease.

  • This medicine may cause the following problems:Heart problemsInfusion-related reactionsLung or breathing problems

  • This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.

Herceptin side effects

Serious Side Effects

  • Unusual bleeding, bruising, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, trouble breathing, or fast, slow, or uneven heartbeat

  • Fever, chills, cough, runny or stuffy nose, sore throat, and body aches

  • Lightheadedness, dizziness, or fainting, fever, vomiting, headache

  • Rapid weight gain, swelling in your hands, ankles, or feet

Less Serious Side Effects

  • Sores or white patches on your lips, mouth, or throat

  • Diarrhea, nausea

  • Headache

  • Joint or back pain