What is Humate-P: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jul 22, 2021

Humate-P overview

BRAND NAMES:

  • Alphanate, Humate-P, Wilate

Generic Names:

  • Humate-P

Uses:

  • Controls and prevents bleeding in hemophilia A and von Willebrand disease. Also used to prevent bleeding during surgery.

Therapeutic Classes:

  • Antihemophilic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Humate-P used for?

Humate-P contains special proteins that are used to treat hemophilia A, von Willebrand disease, bleeding, and other conditions as prescribed by your doctor. Patients with these conditions, have either missing or low levels of these proteins and are at risk of excessive bleeding after an injury or surgery. Humate-P temporarily replaces these missing proteins and decreases bleeding. It may be used by children and adults. It is available as an injection.

What form(s) does Humate-P come in

  • Injectable

What are common Humate-P doses?

  • Solution Reconstituted 1000-2400UNIT

Common Humate-P prescriptions

  • Humate-P
    1000-2400unit solution reconstituted

  • Humate-P
    250-600unit solution reconstituted

  • Humate-P
    500-1200unit solution reconstituted

How to take Humate-P

  • Swirl the Wilate® vial gently to dissolve the powder. Do not shake. Do not use the mixed liquid if it is cloudy, discolored, or has particles in it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Injection route: Call your doctor or pharmacist for instructions.

  • You may store the Wilate® unopened vial in the refrigerator for up to 36 months. Do not freeze. You may also store it at room temperature for up to 6 months. Do not place it back in the refrigerator once stored at room temperature. Use the medicine right away after mixing it.

  • Injection route: A nurse or other health provider will give you this medicine.

  • Injection route: You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Injection route: Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

What to do if you miss a dose of Humate-P

Humate-P contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to antihemophilic factor, von Willebrand factor, or to human plasma-derived products.

Humate-P warnings

  • Tell your doctor if you are pregnant or breastfeeding, you received a hepatitis A or hepatitis B vaccine shot, or you ever had a blood clot.

  • This medicine may increase your risk for blood clots, especially if you have a history of clots.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Call your doctor right away if you continue to have bleeding problems even after you use this medicine. Also call if your medicine does not seem to be working as well as usual.

  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. Although the risk is low, talk with your doctor if you have concerns.

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Unusual bleeding or bruising

  • Yellow skin or eyes

Humate-P interactions

  • This medicine may increase your risk for blood clots, especially if you have a history of clots.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Call your doctor right away if you continue to have bleeding problems even after you use this medicine. Also call if your medicine does not seem to be working as well as usual.

  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. Although the risk is low, talk with your doctor if you have concerns.

  • Tell your doctor if you are pregnant or breastfeeding, you received a hepatitis A or hepatitis B vaccine shot, or you ever had a blood clot.

Humate-P side effects

Serious Side Effects

  • Warmth or redness in your face, neck, arms, or upper chest

  • Yellow skin or eyes

  • Numbness or weakness on one side of your body, sudden or severe headache, problems with speech, vision, or walking

  • Unusual bleeding or bruising

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, coughing up blood, or troubled breathing

  • Fever or chills, headache

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Lightheadedness, dizziness, fainting

  • Pain or weakness in your calf

Less Serious Side Effects

  • Pain, itching, burning, stinging, swelling, or a lump under your skin where the needle is placed

  • Nausea, vomiting, or loss of appetite

  • Joint or muscle pain

Medicamentos A-Z:

Ver todos
ABCDEFGHIJKLMNOPQRSTUVWXYZ