What is Isosulfan Blue? Uses, warnings & side effects

Updated May 14, 2025  •  Published Sep 29, 2023

Isosulfan Blue overview

BRAND NAMES:

  • Isosulfan Blue Novaplus, Lymphazurin, PremierPro Rx Isosulfan Blue

Generic Names:

  • Isosulfan Blue

Uses:

  • Used during a medical test or imaging procedure to help organs or other body parts show up better.

Therapeutic Classes:

  • Diagnostic Agent, Lymphatic Visualization

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Isosulfan Blue used for?

What form(s) does Isosulfan Blue come in?

  • Injectable

What are common Isosulfan Blue dosages?

  • Vial 5ml of 1%

Isosulfan Blue images - What does Isosulfan Blue look like?

  • Isosulfan Blue
    5ml of 1% vial

How to take Isosulfan Blue

  • A health caregiver will give you this medicine. It is given as a shot under your skin.

What to do if you miss a dose of Isosulfan Blue

Isosulfan Blue contraindications - Who shouldn't take Isosulfan Blue?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to isosulfan blue or triphenylmethane.

Isosulfan Blue warnings

  • Tell your doctor if you are pregnant or breastfeeding, if you had an allergic reaction to any dye or medicine given during a test or procedure, or if you have a history of asthma or allergies.

  • This medicine may cause your urine to turn blue for up to 24 hours after you receive it. Talk to your doctor if you have any questions.

  • Pain, swelling, itching, blistering, rash, or a lump under your skin where the shot was given

Isosulfan Blue interactions & what to avoid when taking Isosulfan Blue

  • Tell your doctor if you are pregnant or breastfeeding, if you had an allergic reaction to any dye or medicine given during a test or procedure, or if you have a history of asthma or allergies.

  • This medicine may cause your urine to turn blue for up to 24 hours after you receive it. Talk to your doctor if you have any questions.

Isosulfan Blue side effects - How does Isosulfan Blue make you feel?

Serious Side Effects

  • Confusion, dizziness, lightheadedness, skin rash, sweating

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Pain, swelling, itching, blistering, rash, or a lump under your skin where the shot was given

Less Serious Side Effects

  • Blue discoloration of the skin

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