What is Ketoprofen ER? Uses, warnings & side effects

Updated May 14, 2025  •  Published Jun 17, 2021

Ketoprofen ER overview

BRAND NAMES:

  • Orudis, Orudis KT, Oruvail

Generic Names:

  • Ketoprofen Er

Uses:

  • Treats pain and arthritis. This medicine is an NSAID.

Therapeutic Classes:

  • Analgesic, Antimigraine, Antirheumatic, Central Nervous System Agent, Musculoskeletal Agent

Forms:

  • Capsule, Long Acting Capsule, Tablet, Long Acting Tablet, Coated Tablet

How it’s taken:

  • By mouth

What is Ketoprofen ER used for?

Ketoprofen ER are used to relieve severe pain caused by osteoarthritis and rheumatoid arthritis. It reduces the production of substances responsible for causing pain and inflammation. This medication is available as a prescription and as an over the counter drug.

What form(s) does Ketoprofen ER come in?

  • Capsule

  • Long Acting Capsule

  • Tablet

  • Long Acting Tablet

  • Coated Tablet

What are common Ketoprofen ER dosages?

  • Capsule 200mg

Ketoprofen ER images - What does Ketoprofen ER look like?

  • Ketoprofen ER
    200mg capsule

How to take Ketoprofen ER

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Swallow the extended-release capsule whole. Do not crush, break, or chew it.

  • Oral routeIt is best to take this medicine with food or milk.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Ketoprofen ER

Ketoprofen ER contraindications - Who shouldn't take Ketoprofen ER?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to ketoprofen, aspirin, or another NSAID pain and arthritis medicine, such as diclofenac, ibuprofen, naproxen, or celecoxib.

Ketoprofen ER warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have a history of ulcers or other stomach problems. Tell your doctor if you have bleeding problems, liver disease, kidney disease, asthma, high blood pressure, congestive heart failure (CHF), or other heart or circulation problems.

  • This medicine may cause the following problems: Bleeding in your stomach or intestinesHigher risk of heart attack or strokeSerious skin reactionsLiver problems

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Change in how much or how often you urinate

  • Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking

  • Pain in your lower leg (calf)

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Unusual bleeding, bruising, or weakness

  • Vomiting blood or material that looks like coffee grounds

Ketoprofen ER interactions & what to avoid when taking Ketoprofen ER

  • Do not use any other NSAID medicine unless your doctor says it is okay. Some other NSAIDs are aspirin, diclofenac, ibuprofen, and naproxen.

  • Some medicines can affect how ketoprofen works. Tell your doctor if you are taking any of the following: A blood thinner such as warfarinA diuretic (water pill) such as furosemide, hydrochlorothiazide (HCTZ), or torsemideLithiumMethotrexateProbenecidSteroid medicine

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Ketoprofen ER side effects - How does Ketoprofen ER make you feel?

Serious Side Effects

  • Unusual bleeding, bruising, or weakness

  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Bloody or black, tarry stools

  • Change in how much or how often you urinate

  • Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting

  • Vomiting blood or material that looks like coffee grounds

  • Pain in your lower leg (calf)

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Rapid weight gain, swelling in your hands, ankles, or feet

Less Serious Side Effects

  • Drowsiness, dizziness, or nervousness

  • Headache

  • Constipation, gas, or upset stomach

  • Vision changes

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