What is Kisqali (400 MG Dose)? Uses, warnings & side effects

Updated May 14, 2025  •  Published Jan 29, 2022

Kisqali (400 MG Dose) overview

BRAND NAMES:

  • Kisqali Femara Co-Pack, Kisqali

Generic Names:

  • Kisqali (400 Mg Dose)

Uses:

  • Treats breast cancer.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Kisqali (400 MG Dose) used for?

What form(s) does Kisqali (400 MG Dose) come in?

  • Tablet

What are common Kisqali (400 MG Dose) dosages?

  • Box 42 Tablets Therapy Pack

Kisqali (400 MG Dose) images - What does Kisqali (400 MG Dose) look like?

  • Kisqali (400 MG Dose)
    42 tablets therapy pack box

How to take Kisqali (400 MG Dose)

  • This medicine is taken together with letrozole or fulvestrant. It is important that you take both medicines at the same time each day, preferably in the morning. Follow your doctor's instructions on when to take these medicines.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in the original package.

  • Swallow the tablet whole. Do not crush, break, or chew it.

  • Missed dose: If you miss a dose or vomit after you take this medicine, do not take another dose the same day. Wait and take your next dose when you normally would.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

What to do if you miss a dose of Kisqali (400 MG Dose)

Kisqali (400 MG Dose) contraindications - Who shouldn't take Kisqali (400 MG Dose)?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to ribociclib, or if you are pregnant or breastfeeding.

Kisqali (400 MG Dose) warnings

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Women should use an effective form of birth control during treatment and for at least 3 weeks after the last dose.

  • This medicine may cause the following problems:Interstitial lung disease or pneumonitis (can be life-threatening)Heart rhythm problem (including QT prolongation)Liver problemsChanges in the number of blood cells, which can increase your risk for infection or bleeding

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you have kidney disease, liver disease, congestive heart failure, heart disease, heart rhythm problem, recent heart attack, lung problems, or any type of infection.

  • Do not breastfeed while you are taking this medicine and for 3 weeks after your last dose.

  • Talk with your doctor before using this medicine if you plan to have children. Some men who use this medicine have become infertile (unable to have children).

Kisqali (400 MG Dose) interactions & what to avoid when taking Kisqali (400 MG Dose)

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • Some medicines can affect how ribociclib works. Tell your doctor if you are using any of the following:Alfentanil, bepridil, boceprevir, carbamazepine, chloroquine, clarithromycin, conivaptan, cyclosporine, dihydroergotamine, ergotamine, everolimus, fentanyl, halofantrine, haloperidol, indinavir, itraconazole, ketoconazole, lopinavir/ritonavir, methadone, midazolam, moxifloxacin, nefazodone, nelfinavir, ondansetron, phenytoin, pimozide, posaconazole, quinidine, rifampin, ritonavir, saquinavir, sirolimus, St John's wort, tacrolimus, tamoxifen, or voriconazoleMedicine to treat heart rhythm problems

Kisqali (400 MG Dose) side effects - How does Kisqali (400 MG Dose) make you feel?

Serious Side Effects

  • Fast, pounding, or uneven heartbeat

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Chest pain, troubled breathing

  • Fever, chills, cough, sore throat, body aches

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fainting, dizziness, lightheadedness

Less Serious Side Effects

  • Back or joint pain

  • Constipation, diarrhea

  • Hair loss

  • Headache

  • Tiredness

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