Tacrolimus is a generic drug that is used with other medications to prevent rejection of an organ after a transplant surgery of the kidney, heart, or liver. Similar brand-name drugs include Prograf, Astagraf XL, Envarsus XR, and Hecoria. On average, the retail price of Tacrolimus is about $306.11 for 1, 30gm of 0.1% tube of ointment. You can save on this cost by using a SingleCare Tacrolimus coupon at participating pharmacies such as CVS, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, Walgreens, and Duane Reade. Our lowest price for Tacrolimus is $35.58 for 1, 30gm of 0.1% tube of ointment.
Edit your dosage
14 capsule, 0.5mgEdit
Unlock members-only prices.Free signup.
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.

Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Tacrolimus is a generic drug that is used with other medications to prevent rejection of an organ after a transplant surgery of the kidney, heart, or liver. Similar brand-name drugs include Prograf, Astagraf XL, Envarsus XR, and Hecoria. On average, the retail price of Tacrolimus is about $306.11 for 1, 30gm of 0.1% tube of ointment. You can save on this cost by using a SingleCare Tacrolimus coupon at participating pharmacies such as CVS, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, Walgreens, and Duane Reade. Our lowest price for Tacrolimus is $35.58 for 1, 30gm of 0.1% tube of ointment.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Tacrolimus Retail Price | Tacrolimus SingleCare Price |
|---|---|---|
| CVS Pharmacy | $232.68 | $57.19 |
| Walmart | $185.00 | $60.70 |
| Walgreens | $113.50 | $78.59 |
| Kroger Pharmacy | $271.99 | $60.51 |
| Albertsons Pharmacy | $231.48 | $74.64 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Tacrolimus is a generic drug that is used with other medications to prevent rejection of an organ after a transplant surgery of the kidney, heart, or liver. Similar brand-name drugs include Prograf, Astagraf XL, Envarsus XR, and Hecoria. On average, the retail price of Tacrolimus is about $306.11 for 1, 30gm of 0.1% tube of ointment. You can save on this cost by using a SingleCare Tacrolimus coupon at participating pharmacies such as CVS, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, Walgreens, and Duane Reade. Our lowest price for Tacrolimus is $35.58 for 1, 30gm of 0.1% tube of ointment.
With no insurance coverage, your Tacrolimus cost will be approximately $306.11 for 1, 30gm of 0.1% tube of ointment. You can reduce this total by using a SingleCare Tacrolimus coupon. Pay just $35.58 for your Tacrolimus fill of 1, 30gm of 0.1% tube of ointment when you use SingleCare's coupons at neighborhood drugstores such as Harris Teeter, Walgreens, and Duane Reade.
There are varying costs for Tacrolimus depending on the type of health insurance coverage that you have. Speak to your insurance provider directly to determine how much Tacrolimus will cost under the plan you're registered with. SingleCare is a more convenient and easy way to fill your prescription. Use our SingleCare Tacrolimus prescription discount coupon and pay only $35.58 for 1, 30gm of 0.1% tube of ointment for your prescription refills at local pharmacies.
Tacrolimus is covered by Medicare Part D and Medicare Advantage plans. Under your Medicare plan, the typical copay for this drug will range between 0–$191. If you're not covered by a Medicare plan, a SingleCare prescription discount card can help you to cut your costs down to as little as $35.58 for 1, 30gm of 0.1% tube of ointment. These savings are available when you use our savings card at participating pharmacies.
Prograf, Astagraf XL, and Envarsus XRare similar brand-name versions of Tacrolimus. Astagraf XL and Envarsus XR are available in brand only and are both once-daily formulations, while Prograf is available in brand and generic and is taken twice daily.
Tacrolimus is a prescription drug that is used with other medications to prevent rejection of organs after a kidney, heart, or liver transplant. Tacrolimus belongs to a class of drugs known as immunosuppressants and works by weakening your immune system to help your body accept the new organ as if it were your own. Usually, the immune system acts as your body's defense agent and fights off and rejects foreign organisms found.
Tacrolimus is available in various forms such as immediate and extended-release capsules. If you are using the granules, read the instructions and other important safety information first before using it. Use only non-plastic cups, spoons, or oral syringes when preparing or taking a dose.
You should not swap different forms, increase your dose, take more often, or stop taking Tacrolimus without first consulting your doctor or healthcare professional. Be sure to visit your local pharmacy to find out more about using our free SingleCare Tacrolimus coupons.
Some but not all common side effects associated with the use of Tacrolimus include opportunistic infection due to weakened immune system, diabetes mellitus, infection, headache, hyperglycemia, hyperkalemia, high blood pressure, mental status changes, nephrotoxicity (with increased blood urea nitrogen and serum creatinine), sensation disorder, and tremor. Lymphoma and other malignancies as well as potentially serious infections are more likely to occur when taking Tacrolimus.
If you are pregnant or planning to become pregnant, consult your healthcare provider before taking Tacrolimus, because the medication can cause harm to the fetus.
Consult with your doctor or healthcare professional for medical advice should any of the side effects persist or become bothersome as this is not a complete list of side effects, others may occur during your Tacrolimus treatment.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved