What is Levocetirizine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Levocetirizine overview

BRAND NAMES:

  • Allergy Relief, Children's Xyzal Allergy 24HR, Xyzal Allergy 24HR, Leader 24HR Allergy Relief, Good Neighbor Pharmacy Allergy Relief

Generic Names:

  • Levocetirizine Dihydrochloride

Uses:

  • Treats symptoms of hay fever, hives, and itching skin.

Therapeutic Classes:

  • Respiratory Agent

Forms:

  • Liquid, Tablet

How it’s taken:

  • By mouth

What is Levocetirizine used for?

Levocetirizine dihydrochloride is a medication used to relieve allergy symptoms. Levocetirizine dihydrochloride belongs to a class of drugs called antihistamines. Levocetirizine dihydrochloride is sold under the brand name Xyzal. This drug was approved by the US FDA in 2007. In the treatment of allergy symptoms, levocetirizine dihydrochloride use is common.

What form(s) does Levocetirizine come in

  • Liquid

  • Tablet

What are common Levocetirizine doses?

  • Tablet 5MG

  • Bottle 30 Tablets

  • Bottle 90 Tablets

  • Bottle 118ML of 2.5MG/5ML

  • Bottle 148ML of 2.5MG/5ML

Common Levocetirizine prescriptions

  • Levocetirizine Dihydrochloride
    118ml of 2.5mg/5ml bottle

  • Levocetirizine Dihydrochloride
    148ml of 2.5mg/5ml bottle

  • Levocetirizine Dihydrochloride
    30 tablets bottle

  • Levocetirizine Dihydrochloride
    90 tablets bottle

  • Levocetirizine Dihydrochloride
    5mg tablet

How to take Levocetirizine

  • Tablet: Swallow it whole. If you need a lower dose, your doctor may tell you to break the tablet in half.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed. This medicine is usually taken in the evening.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Your doctor will tell you how much medicine to use. Do not use more than directed. This medicine is usually taken in the evening.

  • Tablet: Swallow it whole. If you need a lower dose, your doctor may tell you to break the tablet in half.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Levocetirizine

Levocetirizine contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to levocetirizine or cetirizine, or if you have end-stage kidney disease or receiving hemodialysis treatment.

Levocetirizine warnings

  • Call your doctor if your symptoms do not improve or if they get worse.

  • This medicine may make you tired or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, spinal cord lesions, an enlarged prostate, or trouble urinating.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Levocetirizine interactions

  • Do not drink alcohol while you are using this medicine.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Some medicines can affect how levocetirizine works. Tell your doctor if you are using ritonavir or theophylline.

Levocetirizine side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Decrease in how much or how often you urinate, painful urination

Less Serious Side Effects

  • Diarrhea, vomiting

  • Dry mouth

  • Tiredness, sleepiness, drowsiness, weakness

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