What is Lexiscan? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

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Lexiscan overview

BRAND NAMES:

  • Lexiscan

Generic Names:

  • Lexiscan

Uses:

  • Used for a heart stress test.

Therapeutic Classes:

  • Diagnostic Agent, Cardiac Function

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Lexiscan used for?

Lexiscan is a prescription-only medication that is used by patients before they undergo a cardiac nuclear test. Lexiscan works by increasing blood flow in the coronary arteries. Lexiscan is available as an intravenous solution.

What form(s) does Lexiscan come in?

  • Injectable

What are common Lexiscan dosages?

  • Syringe 5ML of 0.4MG/5ML

Lexiscan images - What does Lexiscan look like?

  • Lexiscan
    5ml of 0.4mg/5ml syringe

How to take Lexiscan

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Lexiscan

Lexiscan contraindications - Who shouldn't take Lexiscan?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to regadenoson, or if you have certain heart rhythm problems.

Lexiscan warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, chronic obstructive pulmonary disease (COPD), heart or blood vessel disease, heart valve disease, seizures, or unstable angina.

  • This medicine may cause the following problems:Serious risk of heart attack, stroke, or heart rhythm problemsHigh or low blood pressureSeizures

  • Fast, slow, or uneven heartbeat

  • Lightheadedness, dizziness, or fainting

  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking

Lexiscan interactions & what to avoid when taking Lexiscan

  • Do not eat or drink anything that contains caffeine for at least 12 hours before you receive this medicine. This includes medicines, foods, and drinks with caffeine, such as coffee, tea, and cola drinks.

  • Some foods and medicines can affect how regadenoson works. Tell your doctor if you are using aminophylline, dipyridamole, or theophylline. You may need to stop using dipyridamole for at least 2 days before this test, and stop using aminophylline or theophylline for at least 12 hours before this test.

Lexiscan side effects - How does Lexiscan make you feel?

Serious Side Effects

  • Lightheadedness, dizziness, or fainting

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating

  • Fast, slow, or uneven heartbeat

  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking

Less Serious Side Effects

  • Upset stomach

  • Headache

  • Warmth or redness in your face, neck, arms, or upper chest

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