What is Lysodren: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Lysodren overview

BRAND NAMES:

  • Lysodren

Generic Names:

  • Lysodren

Uses:

  • Treats cancer of the adrenal glands.

Therapeutic Classes:

  • Adrenocortical Suppressant, Steroid Synthesis Inhibitor

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Lysodren used for?

What form(s) does Lysodren come in

  • Tablet

What are common Lysodren doses?

  • Tablet 500MG

Common Lysodren prescriptions

  • Lysodren
    500mg tablet

How to take Lysodren

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Wash your hands immediately if you accidently touch a broken or crushed tablet.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Oral routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.

  • Tablet: Swallow whole. Do not crush, break, or chew it.

  • Wash your hands immediately if you accidently touch a broken or crushed tablet.

  • Tablet: Swallow whole. Do not crush, break, or chew it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Missed dose: Oral routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.

What to do if you miss a dose of Lysodren

Lysodren contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to mitotane, or if you are pregnant or breastfeeding.

Lysodren warnings

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment and for as long as your doctor says to after treatment.

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Tell your doctor if you have liver disease, a serious injury, infection, or illness of any kind. Tell your doctor if you have surgery planned.

  • This medicine may cause the following problems:Adrenal problemsCysts in the ovaries in premenopausal women (have menstrual cycles)

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Lysodren interactions

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may cause severe adrenal problems if you have a serious injury, infection, or illness of any kind. Call your doctor right away if you are sick or injured.

  • Tell your doctor if you are breastfeeding, or if you have liver disease. Tell your doctor if you have surgery planned.

  • Some medicines can affect how mitotane works. Tell your doctor if you are also using a blood thinner (including warfarin).

Lysodren side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Bloating, pelvic pain, vaginal bleeding

  • Changes in skin color, dark freckles

  • Fever, chills, cough, sore throat, body aches

  • Depression, nausea, vomiting, unusual weakness or tiredness, dizziness, fainting

Less Serious Side Effects

  • Diarrhea, loss of appetite

  • Sleepiness

  • Feeling of constant movement of yourself or your surroundings

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.