Mestinon Coupons & Prices

Mestinon (pyridostigmine) is a prescription drug used to increase muscle strength in patients with myasthenia gravis. Myasthenia gravis is an autoimmune disease in which the immune system attacks acetylcholine receptors, which are necessary for normal muscle function. Mestinon prevents the deterioration of acetylcholine so that more acetylcholine is available to bind to remaining receptors in the muscles. This action increases an affected person’s ability to use their muscles. The retail price of Mestinon is $2,160.02. However, a SingleCare Mestinon coupon reduces that price to $27.66. Find out more about this and other ways to save money in our FAQs.

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Mestinon coupon at CVS Pharmacy
$30.66
$ 27.66
$3 off with signupwith signup

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Mestinon coupon at Kroger Pharmacy
$37.59
$ 34.59
$3 off with signupwith signup

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Mestinon coupon at Harris Teeter Pharmacy
$37.59
$ 34.59
$3 off with signupwith signup
Mestinon coupon at Costco Pharmacy
$ 34.99
Mestinon coupon at Food Lion Pharmacy
$ 35.90
Mestinon coupon at Walgreens Pharmacy
$39.79
$ 36.79
$3 off with signupwith signup
$ 39.00
$50.47
$ 47.47
$3 off with signupwith signup
$50.47
$ 47.47
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Mestinon

Mestinon (pyridostigmine) is a prescription drug used to increase muscle strength in patients with myasthenia gravis. Myasthenia gravis is an autoimmune disease in which the immune system attacks acetylcholine receptors, which are necessary for normal muscle function. Mestinon prevents the deterioration of acetylcholine so that more acetylcholine is available to bind to remaining receptors in the muscles. This action increases an affected person’s ability to use their muscles. The retail price of Mestinon is $2,160.02. However, a SingleCare Mestinon coupon reduces that price to $27.66. Find out more about this and other ways to save money in our FAQs.

Mestinon Price History & Information

Price History for Mestinon (Brand) & Pyridostigmine Bromide (Generic)

90 count, tablet, 60mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Mestinon (Brand) & Pyridostigmine Bromide (Generic)

90 count, tablet, 60mg
PharmacyPyridostigmine Bromide Retail PricePyridostigmine Bromide SingleCare Price
CVS Pharmacy$98.10$62.10
Walmart$74.70$41.40
Walgreens$40.37$39.47
Kroger Pharmacy$81.90$37.80
Albertsons Pharmacy$101.70$43.20

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Mestinon

Mestinon (pyridostigmine) is a prescription drug used to increase muscle strength in patients with myasthenia gravis. Myasthenia gravis is an autoimmune disease in which the immune system attacks acetylcholine receptors, which are necessary for normal muscle function. Mestinon prevents the deterioration of acetylcholine so that more acetylcholine is available to bind to remaining receptors in the muscles. This action increases an affected person’s ability to use their muscles. The retail price of Mestinon is $2,160.02. However, a SingleCare Mestinon coupon reduces that price to $27.66. Find out more about this and other ways to save money in our FAQs.

Mestinon FAQs

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

How much does Mestinon cost without insurance?

On average, the price for Mestinon is $2,160.02, but this price may vary based on your particular insurance plan. With a SingleCare coupon for Mestinon, you pay only $27.66 per 90, 60mg tablets.

How much does Mestinon cost with insurance?

The copay cost for Mestinon may vary. With SingleCare, however, the price of Mestinon could be only $27.66. Ask your pharmacist to compare your copay with insurance to your cost with SingleCare savings.

Does Medicare cover Mestinon and how much does it cost?

Most Medicare Advantage and Medicare Part D prescription drug plans usually cover the generic version of Mestinon, pyridostigmine. The cost with Medicare will depend on the plan and its coverage. Medicare patients with a prescription for Mestinon can also consider using a SingleCare Mestinon coupon. The cost of Mestinon, or other prescription medications, with a SingleCare discount card, could be lower than the cost with Medicare.

Is there a generic of Mestinon?

Mestinon is a brand-name prescription drug that contains the active ingredient, pyridostigmine. Generic Mestinon is available as pyridostigmine bromide. Manufacturers of the generic version include Amneal Pharmaceuticals, Elysium Pharmaceuticals, Alvogen, and others.

What is Mestinon?

Mestinon is a prescription drug that improves muscle strength in patients with myasthenia gravis, a progressive autoimmune disease in which the immune system mistakenly attacks the junctions between nerves and muscle cells. More specifically, the immune system attacks receptors of a critical neurotransmitter, acetylcholine, that is involved with normal muscle function.

As the condition progresses, muscles receive fewer and fewer signals from the nervous system. This causes severe muscle weakness and fatigue.

The active ingredient in Mestinon, pyridostigmine, prevents the breakdown of acetylcholine. This allows more acetylcholine to be available at the junctions between nerves and the muscles. More nerve signals are able to get through to the muscles, which helps improve muscle control and strength in affected patients.

Mestinon is taken as a tablet, extended-release tablet, or syrup. The dose will depend on the severity of the underlying condition.

What are the side effects of Mestinon?

The most common side effects of Mestinon include, but are not limited to, nausea, vomiting, diarrhea, indigestion, abdominal cramps, increased urination, increased salivation, increased sweating, watery eyes, and decreased pupil size. Consult a healthcare provider if side effects develop, persist, or worsen.

Serious side effects of Mestinon include muscle cramps, muscle weakness, and muscle twitching. Mestinon may also cause allergic reactions such as hives, rashes, itching, and trouble breathing. Seek immediate medical attention if you experience serious side effects or allergic reactions.

Consult a healthcare provider for medical advice and other possible side effects, drug interactions, warnings, and precautions before taking Mestinon.

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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Where are Mestinon coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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