Mestinon (pyridostigmine) is a prescription drug used to increase muscle strength in patients with myasthenia gravis. Myasthenia gravis is an autoimmune disease in which the immune system attacks acetylcholine receptors, which are necessary for normal muscle function. Mestinon prevents the deterioration of acetylcholine so that more acetylcholine is available to bind to remaining receptors in the muscles. This action increases an affected person’s ability to use their muscles. The retail price of Mestinon is $2,160.02. However, a SingleCare Mestinon coupon reduces that price to $27.66. Find out more about this and other ways to save money in our FAQs.
Edit your dosage
6 cup, 5ml of 60mg/5mlEdit
Unlock members-only prices.Free signup.
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.

Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Mestinon (pyridostigmine) is a prescription drug used to increase muscle strength in patients with myasthenia gravis. Myasthenia gravis is an autoimmune disease in which the immune system attacks acetylcholine receptors, which are necessary for normal muscle function. Mestinon prevents the deterioration of acetylcholine so that more acetylcholine is available to bind to remaining receptors in the muscles. This action increases an affected person’s ability to use their muscles. The retail price of Mestinon is $2,160.02. However, a SingleCare Mestinon coupon reduces that price to $27.66. Find out more about this and other ways to save money in our FAQs.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Pyridostigmine Bromide Retail Price | Pyridostigmine Bromide SingleCare Price |
|---|---|---|
| CVS Pharmacy | $98.10 | $62.10 |
| Walmart | $74.70 | $41.40 |
| Walgreens | $40.37 | $39.47 |
| Kroger Pharmacy | $81.90 | $37.80 |
| Albertsons Pharmacy | $101.70 | $43.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Mestinon (pyridostigmine) is a prescription drug used to increase muscle strength in patients with myasthenia gravis. Myasthenia gravis is an autoimmune disease in which the immune system attacks acetylcholine receptors, which are necessary for normal muscle function. Mestinon prevents the deterioration of acetylcholine so that more acetylcholine is available to bind to remaining receptors in the muscles. This action increases an affected person’s ability to use their muscles. The retail price of Mestinon is $2,160.02. However, a SingleCare Mestinon coupon reduces that price to $27.66. Find out more about this and other ways to save money in our FAQs.
On average, the price for Mestinon is $2,160.02, but this price may vary based on your particular insurance plan. With a SingleCare coupon for Mestinon, you pay only $27.66 per 90, 60mg tablets.
The copay cost for Mestinon may vary. With SingleCare, however, the price of Mestinon could be only $27.66. Ask your pharmacist to compare your copay with insurance to your cost with SingleCare savings.
Most Medicare Advantage and Medicare Part D prescription drug plans usually cover the generic version of Mestinon, pyridostigmine. The cost with Medicare will depend on the plan and its coverage. Medicare patients with a prescription for Mestinon can also consider using a SingleCare Mestinon coupon. The cost of Mestinon, or other prescription medications, with a SingleCare discount card, could be lower than the cost with Medicare.
Mestinon is a brand-name prescription drug that contains the active ingredient, pyridostigmine. Generic Mestinon is available as pyridostigmine bromide. Manufacturers of the generic version include Amneal Pharmaceuticals, Elysium Pharmaceuticals, Alvogen, and others.
Mestinon is a prescription drug that improves muscle strength in patients with myasthenia gravis, a progressive autoimmune disease in which the immune system mistakenly attacks the junctions between nerves and muscle cells. More specifically, the immune system attacks receptors of a critical neurotransmitter, acetylcholine, that is involved with normal muscle function.
As the condition progresses, muscles receive fewer and fewer signals from the nervous system. This causes severe muscle weakness and fatigue.
The active ingredient in Mestinon, pyridostigmine, prevents the breakdown of acetylcholine. This allows more acetylcholine to be available at the junctions between nerves and the muscles. More nerve signals are able to get through to the muscles, which helps improve muscle control and strength in affected patients.
Mestinon is taken as a tablet, extended-release tablet, or syrup. The dose will depend on the severity of the underlying condition.
The most common side effects of Mestinon include, but are not limited to, nausea, vomiting, diarrhea, indigestion, abdominal cramps, increased urination, increased salivation, increased sweating, watery eyes, and decreased pupil size. Consult a healthcare provider if side effects develop, persist, or worsen.
Serious side effects of Mestinon include muscle cramps, muscle weakness, and muscle twitching. Mestinon may also cause allergic reactions such as hives, rashes, itching, and trouble breathing. Seek immediate medical attention if you experience serious side effects or allergic reactions.
Consult a healthcare provider for medical advice and other possible side effects, drug interactions, warnings, and precautions before taking Mestinon.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved