Metafolbic is a generic prescription B-vitamin supplement with vitamins B2, B6, B9, and B12. It is more commonly sold either as “Metafolbic Tab 90” or under the generic name “L-methylfolate / riboflavin / pyridoxine / cyanocobalamin 6/5/50/1 mg 90.” Prescribing informion on Metafolbic is not available at this time, but Vitamin B supplements are typically prescribed to treat vitamin B deficiency anemia or prescribed to patients to either prevent or treat serious vitamin B deficiencies as a result of drug side effects, pregnancy, drug abuse, illness, or some other cause. The retail price of Metafolbic is $105.49, but a SingleCare Metafolbic coupon brings this cost down to $72.58, if prescribed by a healthcare professional.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Metafolbic is a generic prescription B-vitamin supplement with vitamins B2, B6, B9, and B12. It is more commonly sold either as “Metafolbic Tab 90” or under the generic name “L-methylfolate / riboflavin / pyridoxine / cyanocobalamin 6/5/50/1 mg 90.” Prescribing informion on Metafolbic is not available at this time, but Vitamin B supplements are typically prescribed to treat vitamin B deficiency anemia or prescribed to patients to either prevent or treat serious vitamin B deficiencies as a result of drug side effects, pregnancy, drug abuse, illness, or some other cause. The retail price of Metafolbic is $105.49, but a SingleCare Metafolbic coupon brings this cost down to $72.58, if prescribed by a healthcare professional.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Metafolbic is a generic prescription B-vitamin supplement with vitamins B2, B6, B9, and B12. It is more commonly sold either as “Metafolbic Tab 90” or under the generic name “L-methylfolate / riboflavin / pyridoxine / cyanocobalamin 6/5/50/1 mg 90.” Prescribing informion on Metafolbic is not available at this time, but Vitamin B supplements are typically prescribed to treat vitamin B deficiency anemia or prescribed to patients to either prevent or treat serious vitamin B deficiencies as a result of drug side effects, pregnancy, drug abuse, illness, or some other cause. The retail price of Metafolbic is $105.49, but a SingleCare Metafolbic coupon brings this cost down to $72.58, if prescribed by a healthcare professional.
Without insurance, the price for Metafolbic is $105.49. With a SingleCare Metafolbic coupon, however, Metafolbic costs $72.58 per 30, 6-1-50-5mg tablets. Many prescription dietary supplements are not covered by health insurance. Instead, you could use a SingleCare savings card that can reduce the cost of prescription supplements by as much as 80%.
Your copay for Metafolbic with insurance will vary depending on your insurance plan. Ask your pharmacist to compare your insurance copay to SingleCare. You may find your SingleCare discount card saves you money with SingleCare, Metafolbic costs $72.58. Remember, your health insurance may not cover Metafolbic or other prescription supplements. A SingleCare Metafolbic coupon can reliably save you money on your prescription.
Medicare prescription drug plans are unlikely to cover Metafolbic. Medicare patients should instead make sure to bring a SingleCare Metafolbic coupon to the pharmacy. Metafolbic costs $72.58 at major, pharmacies, such as CVS, Target, Longs Drugs, and others.
Metafolbic is the name of a generic alternative to Cerefolin, a brand-name prescription B-vitamin supplement no longer available in pharmacies. However, many generic over-the-counter B vitamin complex products include the B-vitamins in Metafolbic. Each of these B-vitamins is also available individually as over-the-counter supplements at prices much lower than the price of Metafolbic. As always, consult with your physician about the pros and cons of switching to an over-the-counter alternative. Not all over-the-counter supplements can replace prescription supplements for quality and effectiveness.
Metafolbic is a brand-name prescription B-vitamin supplement with riboflavin (vitamin B2), pyridoxine (vitamin B6), methylfolate (vitamin B9), and cyanocobalamin (vitamin B12). Prescribing information on Metafolbic is not available. These four B-vitamins are usually prescribed to patients with B-vitamin deficiency anemia, who are pregnant, or who are at risk for B-vitamin deficiency due to drug side effects, illness, or poor nutrition.
B vitamins are a key component of the body's use of energy. They are the molecules that run the processes that convert proteins, fats, and carbohydrates into energy. Vitamins B6, B9, and B12 are also the three critical vitamins used in the production of red blood cells.
Common side effects of Metafolbic include but are not limited to upset stomach, nausea, diarrhea, gas, and drowsiness. Allergic reactions to Metafolbic are extremely rare. The large amounts of cyanocobalamin in Metafolbic may cause an allergic reaction in patients with a cobalt allergy.
Take Metafolbic as directed by your physician. Taking excessive amounts of B vitamins can over time result in lasting nerve damage.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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