Nascobal is a vitamin B12 nasal spray that is used to treat certain adults with a vitamin B12 deficiency. It is used to supplement vitamin B12 in people with pernicious anemia who have received vitamin B12 shots and do not have issues with their nervous system. It can also treat vitamin B12 deficiency caused by poor absorption of the vitamin (especially in people who have undergone weight loss surgery), food restrictions, and other reasons. Nascobal is only available with a prescription. The average cost of Nascobal is $910.98 for 4, 1 solution bottles, but you could pay a discounted rate of $246.87 for 4, 1 solution boxes. You can use free Nascobal coupons from SingleCare to save on the retail price of this prescription medication.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Nascobal is a vitamin B12 nasal spray that is used to treat certain adults with a vitamin B12 deficiency. It is used to supplement vitamin B12 in people with pernicious anemia who have received vitamin B12 shots and do not have issues with their nervous system. It can also treat vitamin B12 deficiency caused by poor absorption of the vitamin (especially in people who have undergone weight loss surgery), food restrictions, and other reasons. Nascobal is only available with a prescription. The average cost of Nascobal is $910.98 for 4, 1 solution bottles, but you could pay a discounted rate of $246.87 for 4, 1 solution boxes. You can use free Nascobal coupons from SingleCare to save on the retail price of this prescription medication.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Cyanocobalamin Retail Price | Cyanocobalamin SingleCare Price |
|---|---|---|
| CVS Pharmacy | $662.00 | $307.96 |
| Walgreens | $498.08 | $257.64 |
| Kroger Pharmacy | $766.00 | $578.44 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Nascobal is a vitamin B12 nasal spray that is used to treat certain adults with a vitamin B12 deficiency. It is used to supplement vitamin B12 in people with pernicious anemia who have received vitamin B12 shots and do not have issues with their nervous system. It can also treat vitamin B12 deficiency caused by poor absorption of the vitamin (especially in people who have undergone weight loss surgery), food restrictions, and other reasons. Nascobal is only available with a prescription. The average cost of Nascobal is $910.98 for 4, 1 solution bottles, but you could pay a discounted rate of $246.87 for 4, 1 solution boxes. You can use free Nascobal coupons from SingleCare to save on the retail price of this prescription medication.
If you do not have insurance, the average cost of Nascobal is $910.98 for 4, 1 solution bottles. The actual cash price of Nascobal will vary depending on the quantity and dosage prescribed, as well as the location where you buy it from. Using a coupon from SingleCare may help you save money; you could pay as little as $246.87 for 4, 1 solution boxes on your Nascobal prescription at local pharmacies, such as CVS, Walmart, and Kroger.
Depending on the type of insurance plan you may have, Nascobal costs may vary. Check with your pharmacist or healthcare provider to calculate your copay with insurance coverage.
If your out-of-pocket cost is high for Nascobal, you may be able to use a SingleCare savings card to get your Nascobal prescription medication for a discounted price of $246.87 for 4, 1 solution boxes. Ask your pharmacist to enter your discount card ID before you buy and compare Nascobal prices. In some cases, SingleCare may offer the lowest price.
Medicare Part D plans do not typically cover Nascobal. You’ll have to check with your plan to see if Nascobal is covered under the formulary. If you don’t have sufficient Medicare coverage, you can use a SingleCare discount card to save. With a SingleCare Nascobal coupon, you could pay as little as $246.87 for 4, 1 solution boxes. Ask your pharmacist to run the SingleCare card during your next check out to start saving.
Nascobal is a brand-name prescription drug that is manufactured by Endo Pharmaceuticals. There is no generic version of Nascobal currently available.
Nascobal is the only FDA-approved vitamin B12 nasal spray. It is prescribed as a vitamin B12 supplement for adults with pernicious anemia, a condition in which the body is unable to make enough healthy red blood cells because of a lack of vitamin B12. Nascobal can also be used to treat vitamin B12 deficiency caused by food limitations, other medications, or malabsorption of the vitamin. It may be prescribed after bariatric surgery as a form of long-term vitamin B12 supplementation.
Nascobal is available as a nasal spray that is tasteless and odorless, and it is typically used once a week. Nascobal is clinically proven to help increase and maintain healthy levels of vitamin B12 in the body. It is absorbed directly into the bloodstream after bypassing the GI tract.
Nascobal may be used for other purposes not listed here. If you have any questions, you should read the medication guide provided by your pharmacist or consult with your doctor before using Nascobal.
As with all prescription drugs, you may experience side effects after using Nascobal. Common side effects of Nascobal might include headache, nausea, weakness, runny nose, tingling in the hands or feet, and swelling of the tongue. Serious side effects may include serious allergic reactions, a masked folate deficiency, low potassium or platelet levels in the blood, and weakening of the eye nerve in people with early Leber’s disease.
Seek immediate medical attention if you experience signs or symptoms of an allergic reaction, such as swelling of the face, itching or hives, chest tightness, or trouble breathing.
Do not use Nascobal if you are allergic to cobalt. You should also consult with your healthcare provider about any medical conditions you may have or other medications you may be taking before starting treatment with Nascobal.
This is not a complete list of all possible side effects of Nascobal.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved