What is Nevirapine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Nevirapine overview

BRAND NAMES:

  • Viramune, Viramune XR, Viramune XR

Generic Names:

  • Nevirapine

Uses:

  • Treats HIV infection. HIV causes AIDS. Nevirapine does not cure HIV or AIDS, but combination treatment including nevirapine may slow the progress of the disease.

Therapeutic Classes:

  • Antiretroviral Agent

Forms:

  • Liquid, Tablet, Long Acting Tablet

How it’s taken:

  • By mouth

What is Nevirapine used for?

Nevirapine is an antiviral medication used to treat human immunodeficiency virus (HIV) and works by preventing the virus from multiplying in the body. Nevirapine does not cure for HIV or AIDS.

What form(s) does Nevirapine come in

  • Liquid

  • Tablet

  • Long Acting Tablet

What are common Nevirapine doses?

  • Tablet 200MG

  • Bottle 240ML of 50MG/5ML

Common Nevirapine prescriptions

  • Nevirapine
    240ml of 50mg/5ml bottle

  • Nevirapine
    200mg tablet

How to take Nevirapine

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take all other medicines your doctor has prescribed as part of your combination treatment. Do not change your dose or stop using the medicine unless your doctor tells you to.

  • Shake the oral liquid gently just before you use it. Use a marked measuring spoon, oral syringe, or medicine cup to measure the right dose. If you are using a medicine cup, make sure you drink the full dose of medicine. After you swallow the medicine, add some water to the cup and drink the water. This will help make sure you get the full dose of medicine.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Do not take more than one form of nevirapine at the same time. Talk to your doctor if you have any questions.

  • Take this medicine at the same time each day and do not miss any doses. Contact your doctor or pharmacist ahead of time when your supply is running low so you do not run out.

  • If you stop taking this medicine for more than 7 days, talk to your doctor before you start taking it again.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose:Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose:Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Take this medicine at the same time each day and do not miss any doses. Contact your doctor or pharmacist ahead of time when your supply is running low so you do not run out.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Do not take more than one form of nevirapine at the same time. Talk to your doctor if you have any questions.

  • Take all other medicines your doctor has prescribed as part of your combination treatment. Do not change your dose or stop using the medicine unless your doctor tells you to.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • If you stop taking this medicine for more than 7 days, talk to your doctor before you start taking it again.

  • Shake the oral liquid gently just before you use it. Use a marked measuring spoon, oral syringe, or medicine cup to measure the right dose. If you are using a medicine cup, make sure you drink the full dose of medicine. After you swallow the medicine, add some water to the cup and drink the water. This will help make sure you get the full dose of medicine.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Nevirapine

Nevirapine contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to nevirapine, or if you have moderate or severe liver problems.

Nevirapine warnings

  • Your immune system may get stronger when you start taking this medicine. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you are pregnant, or if you have liver disease (including hepatitis B or C).

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Severe liver problemsSerious skin reactionsChanges in body fat

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

Nevirapine interactions

  • Do not take atazanavir, boceprevir, delavirdine, efavirenz, etravirine, fosamprenavir, itraconazole, ketoconazole, lopinavir/ritonavir, rifampin, rilpivirine, telaprevir, St John's wort, or birth control pills while being treated with this medicine, unless your doctor says it is okay.

  • Some foods and medicines can affect how nevirapine works. Tell your doctor if you are using cisapride, clarithromycin, cyclophosphamide, ergotamine, fluconazole, methadone, rifabutin, other medicine to treat HIV or AIDS (such as fosamprenavir/ritonavir, indinavir, nelfinavir, saquinavir/ritonavir), a narcotic pain reliever (such as fentanyl), medicine to treat seizures (such as carbamazepine, clonazepam, ethosuximide), medicine that weakens the immune system (such as cyclosporine, sirolimus, tacrolimus), medicine to treat heart rhythm problems (such as amiodarone, disopyramide, lidocaine), certain blood pressure medicines (such as diltiazem, nifedipine, verapamil), or a blood thinner (such as warfarin).

  • This medicine may cause the following problems:Severe liver problemsSerious skin reactionsChanges in body fat

  • Your immune system may get stronger when you start taking this medicine. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Nevirapine side effects

Serious Side Effects

  • Blistering, peeling, or red skin rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

Less Serious Side Effects

  • Weight gain around your neck, upper back, breast, or waist

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