What is Nicotine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Nicotine overview

BRAND NAMES:

  • Sunmark Nicotine Transdermal System, Sunmark Nicotine Transdermal System, Premier Value Nicotine Transdermal System, Nicoderm CQ, Nicoderm CQ Clear, Nicotrol, Health Mart Nicotine Transdermal System, Leader Nicotine Transdermal System, Good Neighbor Pharmacy Nicotine

Generic Names:

  • Nicotine

Uses:

  • Helps you quit smoking.

Therapeutic Classes:

  • Smoking Cessation Agent

Forms:

  • Patch

How it’s taken:

  • Absorbed through the skin

What is Nicotine used for?

Nicotine is used to treat symptoms associated with withdrawal from nicotine. Nicotine works by releasing some particles of nicotine into the body to prevent a person from craving cigarettes to slowly allow them to quit their habit. This medication is available as a prescription and as an over the counter drug.

What form(s) does Nicotine come in

  • Patch

What are common Nicotine doses?

  • Box 14 Patch 24 Hour

  • Box 7 Patch 24 Hour

  • Box 28 Patch 24 Hour

  • Box 56 Kit

Common Nicotine prescriptions

  • Nicotine
    14 patch 24 hour box

  • Nicotine
    28 patch 24 hour box

  • Nicotine
    56 kit box

  • Nicotine
    7 patch 24 hour box

How to take Nicotine

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Transdermal routeFold the used patch in half with the sticky sides together. Throw any used patch away so that children or pets cannot get to it. You will also need to throw away old patches after the expiration date has passed.

  • Transdermal routeStore the patches at room temperature in a closed container, away from heat, moisture, and direct light.

  • Keep using this medicine for the full treatment time. If you feel you need to use this medicine for a longer period of time, talk to your doctor.

  • NicoDerm® CQ: This is a 3-step program. If you smoke more than 10 cigarettes per day, start with step 1 followed by step 2 and step 3. If you smoke 10 or fewer cigarettes per day, start with step 2 followed by step 3.Begin using the patch on the morning of your quit day, even if you are not able to stop smoking immediately.Apply the patch at about the same time every day to skin that is clean, dry, and free of hair.Transdermal routeThe patient instructions will show the body areas where you can wear the patch. When putting on each new patch, choose a different place within these areas. Do not put the new patch on the same place you wore the last one. Be sure to remove the old patch before applying a new one. Do not put the patch over irritated skin. Do not use creams or lotions, including sunscreen, on the skin where you apply the patch, because it may not stick well.Apply a new patch if one falls off.If you have vivid dreams or sleep problems, remove the patch at bedtime and apply a new one in the morning.

  • Transdermal routeLeave the patch in its sealed wrapper until you are ready to put it on. Tear the wrapper open carefully. NEVER CUT the wrapper or the patch with scissors. Do not use any patch that has been cut by accident.

  • Transdermal routeWash your hands with soap and water before and after applying a patch.

  • Transdermal routeWash your hands with soap and water before and after applying a patch.

  • Keep using this medicine for the full treatment time. If you feel you need to use this medicine for a longer period of time, talk to your doctor.

  • Transdermal routeFold the used patch in half with the sticky sides together. Throw any used patch away so that children or pets cannot get to it. You will also need to throw away old patches after the expiration date has passed.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • NicoDerm® CQ: This is a 3-step program. If you smoke more than 10 cigarettes per day, start with step 1 followed by step 2 and step 3. If you smoke 10 or fewer cigarettes per day, start with step 2 followed by step 3.Begin using the patch on the morning of your quit day, even if you are not able to stop smoking immediately.Apply the patch at about the same time every day to skin that is clean, dry, and free of hair.Transdermal routeThe patient instructions will show the body areas where you can wear the patch. When putting on each new patch, choose a different place within these areas. Do not put the new patch on the same place you wore the last one. Be sure to remove the old patch before applying a new one. Do not put the patch over irritated skin. Do not use creams or lotions, including sunscreen, on the skin where you apply the patch, because it may not stick well.Apply a new patch if one falls off.If you have vivid dreams or sleep problems, remove the patch at bedtime and apply a new one in the morning.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Transdermal routeLeave the patch in its sealed wrapper until you are ready to put it on. Tear the wrapper open carefully. NEVER CUT the wrapper or the patch with scissors. Do not use any patch that has been cut by accident.

  • Transdermal routeStore the patches at room temperature in a closed container, away from heat, moisture, and direct light.

What to do if you miss a dose of Nicotine

Nicotine contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to nicotine.

Nicotine warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • The opaque NicoDerm® CQ patch may cause skin burns if you have a procedure called a magnetic resonance imaging (MRI) scan. You must remove the patch before an MRI.

  • Pregnant or breastfeeding women should only use this medicine as directed by a doctor. Smoking can seriously harm your unborn child. Try to stop smoking without using medicine. Although this medicine is believed to be safer than smoking, the risks of its use during pregnancy are not fully known.

  • Tell your doctor if you have heart disease, heart rhythm problems, high blood pressure, or you had a recent heart attack. Tell your doctor if you have an allergy to adhesive tape.

  • This medicine may cause the following problems:High blood pressureIncrease in heart rate

Nicotine interactions

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you have heart disease, heart rhythm problems, high blood pressure, or you had a recent heart attack. Tell your doctor if you have an allergy to adhesive tape.

  • This medicine may cause the following problems:High blood pressureIncrease in heart rate

  • Pregnant or breastfeeding women should only use this medicine as directed by a doctor. Smoking can seriously harm your unborn child. Try to stop smoking without using medicine. Although this medicine is believed to be safer than smoking, the risks of its use during pregnancy are not fully known.

  • The opaque NicoDerm® CQ patch may cause skin burns if you have a procedure called a magnetic resonance imaging (MRI) scan. You must remove the patch before an MRI.

Nicotine side effects

Serious Side Effects

  • Fast, slow, pounding, or uneven heartbeat

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dizziness, headache, upset stomach, drooling, vomiting, diarrhea, cold sweats, blurred vision, trouble hearing, confusion, fainting, or weakness

Less Serious Side Effects

  • Mild skin redness, itching, burning, or tingling where you wear the patch

  • Vivid dreams or trouble sleeping