What is Ninlaro: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Ninlaro overview

BRAND NAMES:

  • Ninlaro

Generic Names:

  • Ninlaro

Uses:

  • Treats multiple myeloma.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Capsule

How it’s taken:

  • By mouth

What is Ninlaro used for?

Ninlaro is a cancer medication that works by interfering with the growth and spread of cancer cells in the body. It is used along with other medication to treat bone marrow cancer (multiple myeloma).

What form(s) does Ninlaro come in

  • Capsule

What are common Ninlaro doses?

  • Box 1 Capsules

  • Blister 1 Capsules

Common Ninlaro prescriptions

  • Ninlaro
    1 capsules blister

  • Ninlaro
    1 capsules box

  • Ninlaro
    3 capsules box

How to take Ninlaro

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take this medicine at the same time and on the same day of the week every week. Take it at least 1 hour before or at least 2 hours after food.

  • Swallow the capsule whole. Do not open, crush, or chew it.

  • Do not handle crushed or broken capsules. Wash your skin with soap and water if the powder from inside the capsule touches your skin. If the medicine gets into your eyes, rinse them with water.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep your medicine in the original package until you are ready to use it.

  • Missed dose: If your next regular dose is more than 72 hours away, take your medicine as soon as you can. If your next dose is less than 72 hours away, wait until then to take your medicine and skip the missed dose. Do not take extra medicine to make up for a missed dose. If you vomit after taking your dose, do not take more medicine. Just take your next dose at the regular time.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Do not handle crushed or broken capsules. Wash your skin with soap and water if the powder from inside the capsule touches your skin. If the medicine gets into your eyes, rinse them with water.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep your medicine in the original package until you are ready to use it.

  • Swallow the capsule whole. Do not open, crush, or chew it.

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Missed dose: If your next regular dose is more than 72 hours away, take your medicine as soon as you can. If your next dose is less than 72 hours away, wait until then to take your medicine and skip the missed dose. Do not take extra medicine to make up for a missed dose. If you vomit after taking your dose, do not take more medicine. Just take your next dose at the regular time.

  • Take this medicine at the same time and on the same day of the week every week. Take it at least 1 hour before or at least 2 hours after food.

What to do if you miss a dose of Ninlaro

Ninlaro contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to ixazomib, or if you are pregnant or breastfeeding.

Ninlaro warnings

  • Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Both men and women should use effective birth control during treatment and for 90 days after the final dose to keep from getting pregnant.

  • Tell your doctor if you have kidney disease, liver disease, or heart disease.

  • This medicine may cause the following problems:Low platelet counts in your bloodThrombotic microangiopathy (damage in the smallest blood vessels)Liver damage

  • Oral routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Unusual bleeding, bruising, or weakness

  • Weakness in the arms, hands, legs, or feet

Ninlaro interactions

  • Some medicines can affect how ixazomib works. Tell your doctor if you are using carbamazepine, phenytoin, rifampin, or St John's wort.

  • Tell your doctor if you have kidney disease, liver disease, or heart disease.

  • This medicine may cause the following problems:Low platelet counts in your bloodLiver damage

  • Oral routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Ninlaro side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Unusual bleeding, bruising, or weakness

  • Severe or ongoing diarrhea, nausea, vomiting, constipation

  • Fever, tiredness, confusion, loss of vision, seizures

  • Weakness in the arms, hands, legs, or feet

  • Dark urine or pale stools, loss of appetite, stomach pain, yellow skin or eyes

  • Rapid weight gain, swelling in your hands, ankles, or feet

Less Serious Side Effects

  • Mild diarrhea, vomiting, constipation

  • Back pain