Promethazine DM is a generic prescription cough syrup that relieves cough, sneezing, stuffy or runny nose, and other symptoms caused by the common cold or allergies. It contains a combination of Promethazine, an antihistamine, and Dextromethorphan, an antitussive or cough suppressant. The average retail price of Promethazine DM is $38.29 for 120, 6.25-15mg/5ml syrup (quantity in ml)s. However, you may be able to use a SingleCare Promethazine DM coupon to save money and pay only $4.64 for 120, 6.25-15mg/5ml syrup (quantity in ml)s. SingleCare discount cards are accepted at many of your favorite pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 06/19/2026
Promethazine DM is a generic prescription cough syrup that relieves cough, sneezing, stuffy or runny nose, and other symptoms caused by the common cold or allergies. It contains a combination of Promethazine, an antihistamine, and Dextromethorphan, an antitussive or cough suppressant. The average retail price of Promethazine DM is $38.29 for 120, 6.25-15mg/5ml syrup (quantity in ml)s. However, you may be able to use a SingleCare Promethazine DM coupon to save money and pay only $4.64 for 120, 6.25-15mg/5ml syrup (quantity in ml)s. SingleCare discount cards are accepted at many of your favorite pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Promethazine-Dm Retail Price | Promethazine-Dm SingleCare Price |
|---|---|---|
| CVS Pharmacy | $14.62 | $14.62 |
| Walmart | $22.80 | $14.40 |
| Walgreens | $18.08 | $12.00 |
| Kroger Pharmacy | $33.60 | $7.20 |
| Albertsons Pharmacy | $21.68 | $14.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Promethazine DM is a generic prescription cough syrup that relieves cough, sneezing, stuffy or runny nose, and other symptoms caused by the common cold or allergies. It contains a combination of Promethazine, an antihistamine, and Dextromethorphan, an antitussive or cough suppressant. The average retail price of Promethazine DM is $38.29 for 120, 6.25-15mg/5ml syrup (quantity in ml)s. However, you may be able to use a SingleCare Promethazine DM coupon to save money and pay only $4.64 for 120, 6.25-15mg/5ml syrup (quantity in ml)s. SingleCare discount cards are accepted at many of your favorite pharmacies.
Cash-paying customers can expect to pay an average price of $38.29 for 120, 6.25-15mg/5ml syrup (quantity in ml)s of Promethazine DM. However, the price of Promethazine DM can vary depending on pharmacy location and the quantity of medicine prescribed. With a SingleCare Promethazine DM coupon, the current lowest price of Promethazine DM is $4.64 for 120, 6.25-15mg/5ml syrup (quantity in ml)s.
Health insurance plans may help cover Promethazine DM. However, Promethazine DM copay amounts vary by insurance plan. Contact your insurance plan or pharmacist to determine the cost of your Promethazine DM prescription with insurance. Promethazine DM costs $4.64 for 120, 6.25-15mg/5ml syrup (quantity in ml)s with a SingleCare Promethazine DM coupon, which may be lower than your insurance copay. Before you overpay for Promethazine DM, ask your local pharmacist to compare your insurance copay to the price with a SingleCare discount card.
Promethazine DM may be covered by Medicare prescription drug plans. Check your plan for more details. For patients who don’t have Medicare, Promethazine DM is $4.64 for 120, 6.25-15mg/5ml syrup (quantity in ml)s with a SingleCare free prescription drug coupon.
Promethazine DM is a generic prescription drug manufactured by Par and Aidarex Pharmaceuticals, among other generic manufacturers. There is currently no brand-name equivalent.
Promethazine DM is a generic combination drug prescribed to relieve cough, runny nose, stuffy nose, sneezing, and other symptoms caused by the common cold or allergies. It is a prescription medicine that combines an antihistamine called promethazine with a cough suppressant called dextromethorphan.
Promethazine is an antihistamine that works by blocking the effects of histamine, a substance produced by the immune system in response to an allergen. Exposure to an allergen may cause symptoms such as runny nose, congestion, and sneezing.
Dextromethorphan is an opioid-like drug similar to codeine that calms the cough reflex. Unlike opioids, however, dextromethorphan does not relieve pain or produce other effects of opioids, making it a much safer drug for suppressing cough.
Promethazine DM is usually administered as one-half to one teaspoon of syrup once every four to six hours. The dosage can vary depending on an individual’s age, as children typically take a lower dose than adults. It’s important to follow the instructions and medical advice of a healthcare provider for the appropriate dosage to take.
The most common side effects of Promethazine DM include, but are not limited to, drowsiness, dizziness, blurred vision, dry mouth, nausea, and vomiting. Consult a healthcare provider if these side effects persist or worsen.
Other side effects are possible, such as confusion, disorientation, sensitivity to light, fatigue, nervousness, euphoria, involuntary muscle movements, and hallucinations. Serious side effects may also include seizures, severe drowsiness, low blood pressure, breathing problems, and loss of consciousness.
Allergic reactions are rare but possible. Signs and symptoms of an allergic reaction include rash, swelling of the face or throat, and trouble breathing. Consult with your healthcare provider about possible side effects, warnings, and other information before using Promethazine DM.
Promethazine DM is not considered a controlled substance in the United States. In other words, it is not classified by the Drug Enforcement Administration (DEA) as having a high potential for abuse or dependence. However, Promethazine DM is still a prescription medication and should only be used as directed by a healthcare provider.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
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© 2026 SingleCare Administrators. All rights reserved