What is Nupercainal? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

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Nupercainal overview

BRAND NAMES:

  • Hemorrhoidal & Topical Analgesic, Nupercainal

Generic Names:

  • Nupercainal

Uses:

  • Treats mild skin pain and itching. This medicine is a topical anesthetic.

Therapeutic Classes:

  • Anesthetic, Local

Forms:

  • Cream, Ointment

How it’s taken:

  • On the skin

What is Nupercainal used for?

Nupercainal is used to relieve symptoms caused by hemorrhoids including irritation, pain and discomfort around or in the anus. It works by numbing the affected area to provide relief from these. Adults and children over the age of 12 years old can use this medication. Nupercainal is available as an prescription medication and as an over the counter drug.

What form(s) does Nupercainal come in?

  • Cream

  • Ointment

What are common Nupercainal dosages?

  • Tube 28.399999618530273GM of 1%

  • Tube 56.700000762939453GM of 1%

  • Tube 60GM of 1%

Nupercainal images - What does Nupercainal look like?

  • Nupercainal (Topical)
    56.7gm of 1% tube

How to take Nupercainal

  • Your doctor will tell you how much of this medicine to apply and how often. Do not use more medicine or apply it more often than your doctor tells you to.

  • If you are using this medicine without a prescription, follow the instructions on the medicine label. Be careful to not use too much medicine. This is more important if you are using the ointment form. Ask your pharmacist or doctor if you are not sure how much medicine to use.

  • This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. If it does get on these areas, rinse it off right away. Do not swallow any of this medicine.

  • Wash your hands with soap and water before and after using this medicine.

  • Apply a thin layer to the affected area. Rub it in gently.

  • Do not cover the treated area with a bandage unless your doctor has told you to.

  • Wash your hands with soap and water before and after using this medicine.

  • Your doctor will tell you how much of this medicine to apply and how often. Do not use more medicine or apply it more often than your doctor tells you to.

  • If you are using this medicine without a prescription, follow the instructions on the medicine label. Be careful to not use too much medicine. This is more important if you are using the ointment form. Ask your pharmacist or doctor if you are not sure how much medicine to use.

  • Apply a thin layer to the affected area. Rub it in gently.

  • Do not cover the treated area with a bandage unless your doctor has told you to.

  • This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. If it does get on these areas, rinse it off right away. Do not swallow any of this medicine.

What to do if you miss a dose of Nupercainal

  • If you miss a dose or forget to use your medicine, apply it as soon as you can. If it is almost time for your next dose, wait until then to apply the medicine and skip the missed dose.

  • Do not apply extra medicine to make up for a missed dose.

  • Keep all medicine away from children and never share your medicine with anyone.

Nupercainal contraindications - Who shouldn't take Nupercainal?

  • You should not use this medicine if you have had an allergic reaction to dibucaine.

Nupercainal warnings

  • Do not use the ointment form of this medicine on a child, unless your child's doctor has told you to.

  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

  • Make sure your doctor knows if you are pregnant or breastfeeding.

  • If a child swallows any of this medicine, call a doctor or poison center right away.

  • Do not use this medicine for a skin problem that has not been checked by your doctor.

Nupercainal interactions & what to avoid when taking Nupercainal

  • Do not use cosmetics or other skin care products on the treated skin areas.

  • If a child swallows any of this medicine, call a doctor or poison center right away.

  • Do not use the ointment form of this medicine on a child, unless your child's doctor has told you to.

  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

  • Do not use this medicine for a skin problem that has not been checked by your doctor.

Nupercainal side effects - How does Nupercainal make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Increased skin itching or pain

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