What is Omega-3-Acid Ethyl Esters: Uses, Warnings & Interactions
Available only with a prescription, omega-3 acid ethyl esters reduce fats (triglyceride) in the bloodstream. Unlike over-the-counter omega-3 fatty acids, omega-3 fatty acid ethyl esters are semi-synthetic versions in which the fatty acids have been separated from the fat molecule. Both reduce triglyceride levels, but the ethyl esters are more effective.
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Omega-3-Acid Ethyl Esters overview
BRAND NAMES:
Lovaza
Generic Names:
Omega-3 acid ethyl esters
Uses:
Lowers high triglyceride levels.
Therapeutic Classes:
Antihyperlipidemic
Forms:
Capsule
How it’s taken:
By mouth
What is Omega-3-Acid Ethyl Esters used for?
Omega-3 acid ethyl esters reduce triglyceride levels in people diagnosed with severely high fat levels (severe hypertriglyceridemia).
What form(s) does Omega-3-Acid Ethyl Esters come in
Capsule
1 gram
What are common Omega-3-Acid Ethyl Esters doses?
For hypertriglyceridemia: 4 grams once daily or 2 grams twice daily
Common Omega-3-Acid Ethyl Esters prescriptions
Omega-3-acid Ethyl Esters
1gm capsule
How to take Omega-3-Acid Ethyl Esters
Follow all the prescriber’s directions. Do not change the dose without talking to the prescriber.
Please read the Patient Information sheet that comes with this medicine.
Take capsules with food.
Swallow the capsule whole. Do not break, crush, chew, dissolve, or open the capsule.
Store the capsules at room temperature protected from light. Do not freeze.
What to do if you miss a dose of Omega-3-Acid Ethyl Esters
Take a missed dose as soon as it’s remembered.
Do not take more than four capsules per day, and do not exceed that number to make up for a missed dose.
Omega-3-Acid Ethyl Esters contraindications
This medicine is not right for everyone.
Do not use it if you have had an allergic reaction to omega-3-acid ethyl esters.
Omega-3-Acid Ethyl Esters warnings
The healthcare provider will prescribe a lipid-reducing and cholesterol-reducing diet. Maintain that diet while taking omega-3 acid ethyl esters.
Before taking this medication, tell the prescriber if you are pregnant, breastfeeding, or have:
Diabetes
Low thyroid hormones
Liver problems
Pancreas problems
Heart rhythm problems, particularly atrial fibrillation or flutter
Known allergies to fish or shellfish
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Tell other doctors who treat you about taking omega-3 acid ethyl esters. This drug may affect certain blood tests.
Omega-3-Acid Ethyl Esters interactions
Tell the prescriber about all the drugs and supplements being used, particularly blood thinners.
Omega-3-Acid Ethyl Esters side effects
Serious side effects
Talk to a healthcare provider if you notice any signs or symptoms of a possible serious side effect including:
Unusual bleeding or bruising
Fast or uneven heartbeat, flutter, dizziness, fainting
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less serious side effects
Burping
Taste changes
Stomach upset
Sources:
Lovaza drug summary, Prescriber’s Digital Reference (PDR)
Lovaza omega-3 acid ethyl esters capsule prescribing information, DailyMed (NIH National Library of Medicine)
Omega-3 acid ethyl esters capsule prescribing information, DailyMed (NIH National Library of Medicine)
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