Ondansetron Coupons & Prices

Zofran

Ondansetron is a generic prescription drug used to prevent nausea and vomiting from chemotherapy, radiation, or surgery. It is part of a class of drugs called serotonin (5-HT3) receptor antagonists that work by blocking the actions of serotonin, a natural chemical that can cause nausea and vomiting. The average retail price of Ondansetron is $412.98 for 30, 4mg tablets, but you could pay only $14.00 for 30, 4mg tablets with a SingleCare coupon for Ondansetron.

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Ondansetron coupon at Food Lion Pharmacy
$ 14.00

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Ondansetron coupon at Publix Pharmacy
$ 14.47

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Ondansetron coupon at Kroger Pharmacy
$21.72
$ 18.72
$3 off with signupwith signup
Ondansetron coupon at Harris Teeter Pharmacy
$21.72
$ 18.72
$3 off with signupwith signup
Ondansetron coupon at Walgreens Pharmacy
$ 19.31
Ondansetron coupon at Costco Pharmacy
$ 23.98
$ 25.23
$38.05
$ 35.05
$3 off with signupwith signup
$38.05
$ 35.05
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Ondansetron

Ondansetron is a generic prescription drug used to prevent nausea and vomiting from chemotherapy, radiation, or surgery. It is part of a class of drugs called serotonin (5-HT3) receptor antagonists that work by blocking the actions of serotonin, a natural chemical that can cause nausea and vomiting. The average retail price of Ondansetron is $412.98 for 30, 4mg tablets, but you could pay only $14.00 for 30, 4mg tablets with a SingleCare coupon for Ondansetron.

Ondansetron Price History & Information

Price History for Ondansetron Hcl

30 count, tablet, 4mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Ondansetron Hcl

30 count, tablet, 4mg
PharmacyOndansetron Hcl Retail PriceOndansetron Hcl SingleCare Price
CVS Pharmacy$118.24$74.71
Walmart$105.90$38.10
Walgreens$123.82$119.81
Kroger Pharmacy$117.22$24.98
Albertsons Pharmacy$122.10$117.60

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Ondansetron

Ondansetron is a generic prescription drug used to prevent nausea and vomiting from chemotherapy, radiation, or surgery. It is part of a class of drugs called serotonin (5-HT3) receptor antagonists that work by blocking the actions of serotonin, a natural chemical that can cause nausea and vomiting. The average retail price of Ondansetron is $412.98 for 30, 4mg tablets, but you could pay only $14.00 for 30, 4mg tablets with a SingleCare coupon for Ondansetron.

Ondansetron FAQs

Medically reviewed by Josephine BawabPharm.D.
Licensed Pharmacist

How much is Ondansetron with SingleCare?

The generic of Ondansetron costs $14.00 for 30, 4mg tablets with a free Ondansetron coupon from SingleCare. However, you could reduce this cost more depending on your prescription information. Use the dropdown menu above to update your Rx details (i.e., brand/generic, form, dosage, quantity) to find the most accurate price of Ondansetron with SingleCare at your local pharmacies.

How much does Ondansetron cost without insurance?

The average retail cost of Ondansetron without health insurance is $412.98 for 30, 4mg tablets. However, the price can vary depending on different factors, such as the quantity and strength prescribed. For people without insurance, Ondansetron can be expensive. You could save on the price of Ondansetron by using a SingleCare Ondansetron coupon without insurance, which could lower the price to $14.00 for 30, 4mg tablets. 

How much does Ondansetron cost with insurance?

Most insurance plans cover Ondansetron, although the copay amount depends on your insurance plan and its formulary. There may also be quantity limitations of what the insurance plan will cover each month. Check with your insurance company or pharmacy to find out if your plan will cover Ondansetron. If your insurance plan does not cover Ondansetron, you can use a SingleCare prescription coupon to get a discounted price at participating pharmacies.

Does Medicare cover Ondansetron?

Medicare Part D and Medicare Advantage plans may cover Ondansetron. Copay and coinsurance amounts vary depending on the level of insurance coverage you have. Check with your plan or speak to your pharmacy to see if your plan covers Ondansetron and what the total cost will be. For people without Medicare coverage, a SingleCare coupon could help reduce the retail Ondansetron price. The current lowest price with SingleCare is $14.00 for 30, 4mg tablets. 

Does Medicaid cover Ondansetron?

Medicaid usually covers the cost of Ondansetron, depending on the plan and state. If Ondansetron is not covered, consider using a SingleCare coupon to pay as little as $14.00 for 30, 4mg tablets.

What is the brand name of Ondansetron?

Ondansetron is known by the brand name Zofran, which is manufactured by Novartis. 

Ways to save on Ondansetron

If Ondansetron is still too expensive, use a free SingleCare savings card to pay as little as $14.00 for 30, 4mg tablets. Signing up for SingleCare’s loyalty program can help you save even more each month. 

There are other potential ways to save on Ondansetron, such as:

  • Asking your healthcare provider for free samples, although this is not a long-term solution to reduce savings

  • Shopping around to see the cost of Ondansetron at different pharmacies

  • Applying for Medicare Extra Help if eligible

  • Using a flexible spending account (FSA) or health savings account (HSA) if available

  • Switching to an alternative medication

Is there a cheaper alternative to Ondansetron?

Cheaper alternatives to Ondansetron may be available based on your insurance’s formulary. Your plan may prefer switching to the regular or orally-disintegrating tablets (ODT) of Ondansetron. Alternative medications to prevent nausea and vomiting include Phenergan (promethazine) and Compazine (prochlorperazine). Discuss all available options with your healthcare provider to determine the best treatment plan for you.

How to use SingleCare for Ondansetron

You can use SingleCare coupons at most national pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Ondansetron coupon to your digital wallet and show your pharmacist when you pick up your prescription. 

Medically reviewed by Josephine BawabPharm.D.
Licensed Pharmacist

Josephine Bawab, Pharm.D., graduated from Virginia Commonwealth University School of Pharmacy. She began working in community pharmacy in 2012 and has worked for multiple chain pharmacies since then. She is passionate about helping patients and precepting students. She currently works and resides in Virginia, where she is just a few minutes away from the beach.

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Where are Ondansetron coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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