What is Oriahnn: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jun 17, 2021

Oriahnn overview

BRAND NAMES:

  • Oriahnn

Generic Names:

  • Oriahnn

Uses:

  • Treats heavy menstrual bleeding caused by uterine fibroids.

Therapeutic Classes:

Forms:

  • Capsule

How it’s taken:

  • By mouth

What is Oriahnn used for?

What form(s) does Oriahnn come in

  • Capsule

What are common Oriahnn doses?

  • Box 14 Capsules Therapy Pack

Common Oriahnn prescriptions

  • Oriahnn
    1 box (56 capsules), 300-1-0.5mg & 300mg box

How to take Oriahnn

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Take the morning and evening capsules at about the same time each day.

  • Use this medicine within 7 days from the start of your menstrual period.

  • Missed dose: If you miss a dose and it is more than 4 hours from your normal dose, skip the missed dose and go back to your regular dosing schedule. If you miss a dose and it is within than 4 hours of your normal dose, take it as soon possible and go back to your regular dosing schedule. Do not take 2 doses to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • You may receive other medicines (including calcium or vitamin D supplements) to help reduce bone loss.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

What to do if you miss a dose of Oriahnn

Oriahnn contraindications

  • This medicine is not right for everyone. Do not use it if you have had an allergic reaction to elagolix, estradiol, or norethindrone, or if you are pregnant. Do not use it if you have vaginal bleeding that has not been checked by a doctor, liver disease, uncontrolled high blood pressure, problems with blood clots, breast cancer, migraine headaches, or osteoporosis (weak bones).

Oriahnn warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine may cause the following problems:Increased risk of blood clots, heart attack, or strokeLower bone mineral densityIncreased risk of breast cancerChanges in mood or behavior, including thoughts of suicideLiver problemsHigh blood pressureGallbladder diseaseChanges in menstrual bleeding, which may decrease the ability to know if you are pregnantHigh cholesterol and blood sugarHair loss

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine contains a yellow dye called tartrazine, which may cause serious allergic reactions (including asthma). Tell your doctor if you have any allergies (including an aspirin allergy).

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Use another form of birth control (including condoms or spermicide) during treatment and for at least 1 week after the last dose.

  • Make sure any doctor or dentist who treats you knows that you are using this medicine.

  • Tell your doctor if you are breastfeeding, or if you have blood vessel disease, high cholesterol, diabetes, mental problems, gallbladder problems, jaundice (yellow skin or eyes) caused by pregnancy or birth control pills, or a history of fractures. Tell your doctor if you smoke or if you will be having a surgery.

Oriahnn interactions

  • Some foods and medicines can affect how elagolix/estradiol/norethindrone works. Tell your doctor if you are using any of the following:Digoxin, ketoconazole, midazolam, omeprazole, rifampin, rosuvastatinMedicine to treat seizuresOral or inhaled steroid medicine

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • Do not use this medicine together with medicines called OATP 1B1 inhibitors that may increase elagolix levels in the blood. Your doctor should give you a list of these medicines.

Oriahnn side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Extreme energy or restlessness, confusion, agitation, unusual mood or behavior, thoughts or attempts at killing oneself

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Light, heavy, or irregular bleeding during monthly periods

  • Dark urine or pale stools, loss of appetite, yellow skin or eyes

  • Sudden and severe stomach pain, nausea, vomiting, lightheadedness

  • Bone pain, decreased height

  • Numbness or weakness in your arm or leg, or on one side of your body

  • Breast lumps, pain, swelling, tenderness, or discharge

  • Sudden or severe headache, problems with vision, speech, or walking

  • Dry mouth, increased hunger, thirst, or urination

  • Chest pain or tightness, troubled breathing, coughing up blood

  • Pain in your lower leg (calf)

Less Serious Side Effects

  • Thinning or loss of hair

  • Feeling of warmth, redness of the skin

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