What is Oseni: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Oseni overview

BRAND NAMES:

  • Oseni

Generic Names:

  • Alogliptin-Pioglitazone

Uses:

  • Treats type 2 diabetes.

Therapeutic Classes:

  • Antidiabetic

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Oseni used for?

Alogliptin-pioglitazone is used to help treat type 2 diabetes and other conditions as prescribed by your doctor. It is used with diet and exercise to control the level of sugar in the blood. Alogliptin-pioglitazone should not be used to treat type 1 diabetes. It is available to children and adults as a tablet.

What form(s) does Oseni come in

  • Tablet

What are common Oseni doses?

  • Tablet 25-15mg

  • Tablet 25-30mg

  • Tablet 25-45mg

  • Tablet 12.5-30mg

  • Tablet 12.5-15mg

  • Tablet 12.5-45mg

Common Oseni prescriptions

  • Oseni
    25-15mg tablet

  • Oseni
    25-30mg tablet

  • Oseni
    25-45mg tablet

How to take Oseni

  • Swallow the tablet whole. Do not split, crush, break, or chew it.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Oseni

Oseni contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to alogliptin or pioglitazone.

Oseni warnings

  • Tell your doctor if you are pregnant or breastfeeding. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine.

  • Tell your doctor if you have kidney disease, liver disease, heart failure, edema (fluid retention or swelling), macular edema (swelling of the back of the eye), bone problems, or a history of bladder cancer or pancreas problems.

  • This medicine may cause the following problems: Heart failurePancreatitis (swelling of the pancreas)Liver problemsIncreased risk for broken bones (fracture)Increased risk for bladder cancer if you use this medicine for a long timeLow blood sugar

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness

  • Severe joint pain

  • Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion

  • Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness

Oseni interactions

  • Some medicines can affect how alogliptin/pioglitazone works. Tell your doctor if you are using gemfibrozil, rifampin, topiramate, or another diabetes medicine (including insulin).

  • Tell your doctor if you have kidney disease, liver disease, heart failure, edema (fluid retention or swelling), macular edema (swelling of the back of the eye), bone problems, or a history of bladder cancer or pancreas problems.

  • This medicine may cause the following problems: Heart failurePancreatitisLiver damageIncreased risk for broken bonesIncreased risk for bladder cancer if you use this medicine for a long timeLow blood sugar levels

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Oseni side effects

Serious Side Effects

  • Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness

  • Change in how much or how often you urinate, painful urination, lower back or side pain, blood in your urine

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing, tiredness

  • Severe joint pain

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Blistering, peeling, red skin rash

  • Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion

  • Large, hard skin blisters

  • Blurred vision or other vision changes

Less Serious Side Effects

  • Headache

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