What is Paclitaxel: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Paclitaxel overview

BRAND NAMES:

  • PremierPro Rx PACLitaxel, PremierPro Rx PACLitaxel

Generic Names:

  • Paclitaxel

Uses:

  • Treats lung, ovary, and breast cancer and Kaposi sarcoma.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Paclitaxel used for?

What form(s) does Paclitaxel come in

  • Injectable

What are common Paclitaxel doses?

  • Vial 16.700000762939453ML of 100MG/16.7ML

  • Vial 50ML of 300MG/50ML

Common Paclitaxel prescriptions

  • PACLitaxel
    16.7ml of 100mg/16.7ml vial

  • PACLitaxel
    25ml of 150mg/25ml vial

  • PACLitaxel
    50ml of 300mg/50ml vial

  • PACLitaxel
    5ml of 30mg/5ml vial

How to take Paclitaxel

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • You may also receive other medicines to help prevent allergic reactions and nausea or vomiting from paclitaxel.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • You may also receive other medicines to help prevent allergic reactions and nausea or vomiting from paclitaxel.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

What to do if you miss a dose of Paclitaxel

Paclitaxel contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to paclitaxel or polyoxyl 35 castor oil or if you are pregnant.

Paclitaxel warnings

  • Injection routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you are breastfeeding or if you have liver disease, heart disease, or heart rhythm problems. Also tell your doctor if you had an allergic reaction to cyclosporin or teniposide.

  • This medicine may cause the following problems:Severe allergic reactionHeart rhythm problemsHigh blood pressureSevere reaction where the needle is placed (may happen up to 10 days later)

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Unusual bleeding, bruising, or weakness

Paclitaxel interactions

  • Some medicines and foods can affect the way this drug works. Tell your doctor if you are also using atazanavir, buspirone, carbamazepine, clarithromycin, eletriptan, felodipine, gemfibrozil, indinavir, itraconazole, ketoconazole, lovastatin, midazolam, nefazodone, nelfinavir, repaglinide, rifampin, ritonavir, rosiglitazone, saquinavir, sildenafil, simvastatin, telithromycin, or triazolam.

  • Tell your doctor if you are breastfeeding or if you have liver disease, heart disease, or heart rhythm problems. Also tell your doctor if you had an allergic reaction to cyclosporin or teniposide.

  • This medicine may cause the following problems:Severe allergic reactionHeart rhythm problemsHigh blood pressureSevere reaction where the needle is placed (may happen up to 10 days later)

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Paclitaxel side effects

Serious Side Effects

  • Severe redness, pain, swelling, or peeling where the needle is placed

  • Unusual bleeding, bruising, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fast, slow, or uneven heartbeat

  • Fever, chills, cough, sore throat, and body aches

  • Lightheadedness, dizziness, or fainting

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

Less Serious Side Effects

  • Mild redness, tenderness, swelling, or color changes where the needle is placed

  • Muscle, bone, or joint pain

  • Hair loss

  • Mild nausea, vomiting, diarrhea

  • Sores or white patches on your lips, mouth, or throat

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