What is Pentamidine Isethionate: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 9, 2021

Pentamidine Isethionate overview

BRAND NAMES:

  • Nebupent

Generic Names:

  • Pentamidine Isethionate

Uses:

  • Helps treat and prevent Pneumocystis carinii pneumonia (PCP) in patients with human immunodeficiency virus (HIV).

Therapeutic Classes:

  • Antiprotozoal

Forms:

  • Spray

How it’s taken:

  • By breathing

What is Pentamidine Isethionate used for?

What form(s) does Pentamidine Isethionate come in

  • Spray

What are common Pentamidine Isethionate doses?

  • Solution Reconstituted 300MG

Common Pentamidine Isethionate prescriptions

  • Pentamidine Isethionate
    300mg solution reconstituted

How to take Pentamidine Isethionate

  • Your doctor will tell you how much medicine to use and how often.

  • A machine called a nebulizer turns the medicine into a fine spray that you breathe into your lungs. You will need to use the nebulizer for about 35 to 40 minutes, or until the medicine in the dose chamber is gone.

  • A nurse or other caregiver trained to use the nebulizer will give your medicine. Sometimes you, someone in your family, or a friend can be taught to give your treatment.

  • Your doctor will tell you how much medicine to use and how often.

  • A machine called a nebulizer turns the medicine into a fine spray that you breathe into your lungs. You will need to use the nebulizer for about 35 to 40 minutes, or until the medicine in the dose chamber is gone.

  • A nurse or other caregiver trained to use the nebulizer will give your medicine. Sometimes you, someone in your family, or a friend can be taught to give your treatment.

What to do if you miss a dose of Pentamidine Isethionate

  • Use the missed dose as soon as possible, unless it is almost time for your next dose.

  • Skip the missed dose if it is almost time for your next regular dose.

  • You should not use two doses at the same time.

Pentamidine Isethionate contraindications

  • You should not use this medicine if you have had an allergic reaction to pentamidine.

Pentamidine Isethionate warnings

  • Fever, chills, night sweats, tiredness, or appetite loss may mean that your infection is getting worse or you have a new infection. Call your doctor as soon as possible if you have the symptoms listed above.

  • Talk with your doctor before using the medicine if you are pregnant or breastfeeding.

  • Make sure your doctor knows if you have diabetes, high or low blood pressure, anemia, asthma, or heart, liver, or kidney disease.

  • When you breathe in the medicine, you may cough or have trouble breathing, especially if you smoke or have asthma. Your doctor may give you a medicine to use before your pentamidine treatment to help you breathe easier.

Pentamidine Isethionate interactions

  • Make sure your doctor knows if you have diabetes, high or low blood pressure, anemia, asthma, or heart, liver, or kidney disease.

  • When you breathe in the medicine, you may cough or have trouble breathing, especially if you smoke or have asthma. Your doctor may give you a medicine to use before your pentamidine treatment to help you breathe easier.

  • Fever, chills, night sweats, tiredness, or appetite loss may mean that your infection is getting worse or you have a new infection. Call your doctor as soon as possible if you have the symptoms listed above.

  • Do not mix any other medicine with pentamidine in the nebulizer. You should not use the nebulizer to give any other medicines, unless your doctor tells you to.

Pentamidine Isethionate side effects

Serious Side Effects

  • Coughing, wheezing, or trouble breathing

  • Skin rash, itching, or hives

  • Sharp chest pains

  • Dizziness

Less Serious Side Effects

  • Dizziness

  • Change in taste or a metallic taste in your mouth

  • Nausea, appetite loss

  • Sore throat or hoarseness

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.