What is Perjeta: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Perjeta overview

BRAND NAMES:

  • Perjeta

Generic Names:

  • Perjeta

Uses:

  • Treats breast cancer.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Perjeta used for?

Perjeta is used to treat women with human epidermal growth factor receptor 2 (HER2-positive) breast cancer that has spread to other parts of the body. It is used along with trastuzumab and docetaxel to treat this condition. Perjeta stunts the growth of cancer cells. It is indicated for use by adult women and is available as a liquid.

What form(s) does Perjeta come in

  • Injectable

What are common Perjeta doses?

  • Vial 14ML of 420MG/14ML

Common Perjeta prescriptions

  • Perjeta
    14ml of 420mg/14ml vial

How to take Perjeta

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

What to do if you miss a dose of Perjeta

Perjeta contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to pertuzumab, or if you are pregnant.

Perjeta warnings

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine and for 7 months after your last dose.

  • Tell your doctor if you are breastfeeding, or if you have heart disease, heart failure, high blood pressure, or heart rhythm problems.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may cause the following problems:New or worsening heart failureInfusion reactions

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

Perjeta interactions

  • This medicine may cause the following problems:New or worsening heart failureInfusion reactions

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Tell your doctor if you are breastfeeding, or if you have heart disease, heart failure, high blood pressure, or heart rhythm problems.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment and for 7 months after your last dose.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Perjeta side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, trouble breathing, fast or uneven heartbeat, dizziness, fainting

  • Fever, chills, headache, vomiting

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Unusual bleeding, bruising, or weakness

Less Serious Side Effects

  • Decreased appetite

  • Sores or white patches on your lips, mouth, or throat

  • Hair loss

  • Tiredness

  • Diarrhea, nausea, stomach upset

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