What is Podofilox: Uses, Warnings & Interactions

What is Podofilox: Uses, Warnings & Interactions

Updated May 14, 2025 • Published Dec 30, 2020

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Podofilox overview

BRAND NAMES:

Condylox, Podofilox

Generic Names:

Podofilox

Uses:

Treats genital warts.

Therapeutic Classes:

Keratolytic

Forms:

Gel/Jelly, Liquid

How it’s taken:

On the skin

What is Podofilox used for?

What form(s) does Podofilox come in

Gel/Jelly
Liquid

What are common Podofilox doses?

Bottle 1GM of
Bottle 3.5ML of 0.5%

Common Podofilox prescriptions

Podofilox
3.5ml of 0.5% bottle
Podofilox
3.5gm of 0.5% tube

How to take Podofilox

Use this medicine as directed. Your caregiver should show you how and where to apply the medicine.
Use only on the warts. Do not get this medicine on normal skin or in your eyes.
Topical application routeWash your hands with soap and water before and after you use this medicine.
Put a small amount of medicine on the warts with the cotton swab that comes with your medicine. Let the medicine dry completely before you let anything touch the treated area. This includes other skin areas, such as the other leg.
Throw away the used cotton swab after you apply the medicine.
The usual schedule is to use this medicine for 3 days, then to not use it for 4 days. Your doctor might tell you to repeat this cycle for another 3 days on, 4 days off, if the warts are not healed.
Do not have sex on the days that you use this medicine.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.
Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
Do not have sex on the days that you use this medicine.
Topical application routeWash your hands with soap and water before and after you use this medicine.
Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
The usual schedule is to use this medicine for 3 days, then to not use it for 4 days. Your doctor might tell you to repeat this cycle for another 3 days on, 4 days off, if the warts are not healed.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.
Use only on the warts. Do not get this medicine on normal skin or in your eyes.
Throw away the used cotton swab after you apply the medicine.
Put a small amount of medicine on the warts with the cotton swab that comes with your medicine. Let the medicine dry completely before you let anything touch the treated area. This includes other skin areas, such as the other leg.
Use this medicine as directed. Your caregiver should show you how and where to apply the medicine.

What to do if you miss a dose of Podofilox

Podofilox contraindications

This medicine is not right for everyone. Do not use it if you had an allergic reaction to podofilox.

Podofilox warnings

Tell your doctor if you are pregnant or breastfeeding.
Call your doctor if the warts are not gone after 4 weeks of treatment.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Podofilox interactions

Tell your doctor if you are pregnant or breastfeeding.
Call your doctor if the warts are not gone after 4 weeks of treatment.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Podofilox side effects

Serious Side Effects

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Bleeding, swelling, or severe pain

Less Serious Side Effects

Mild redness, burning, itching, pain, swelling