Nexlizet is a prescription medication that helps manage high cholesterol levels when used with statin therapy and appropriate lifestyle changes. It combines the active ingredients bempedoic acid and ezetimibe to help lower LDL cholesterol in the blood. Nexlizet is a brand-name drug that is not currently available in a generic form. The average retail price of Nexlizet is $583.23 for 30, 180-10mg tablets. However, with a SingleCare prescription discount card, you may be able to access Nexlizet at lower prices, potentially as low as $380.14 for 30, 180-10mg tablets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Nexlizet is a prescription medication that helps manage high cholesterol levels when used with statin therapy and appropriate lifestyle changes. It combines the active ingredients bempedoic acid and ezetimibe to help lower LDL cholesterol in the blood. Nexlizet is a brand-name drug that is not currently available in a generic form. The average retail price of Nexlizet is $583.23 for 30, 180-10mg tablets. However, with a SingleCare prescription discount card, you may be able to access Nexlizet at lower prices, potentially as low as $380.14 for 30, 180-10mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Nexlizet Retail Price | Nexlizet SingleCare Price |
|---|---|---|
| CVS Pharmacy | $498.00 | $421.80 |
| Walmart | $504.00 | $418.80 |
| Walgreens | $507.00 | $419.70 |
| Kroger Pharmacy | $504.00 | $383.10 |
| Albertsons Pharmacy | $471.60 | $419.70 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Nexlizet is a prescription medication that helps manage high cholesterol levels when used with statin therapy and appropriate lifestyle changes. It combines the active ingredients bempedoic acid and ezetimibe to help lower LDL cholesterol in the blood. Nexlizet is a brand-name drug that is not currently available in a generic form. The average retail price of Nexlizet is $583.23 for 30, 180-10mg tablets. However, with a SingleCare prescription discount card, you may be able to access Nexlizet at lower prices, potentially as low as $380.14 for 30, 180-10mg tablets.
The cost of medications like Nexlizet can vary depending on the pharmacy location and the prescribed quantity. On average, Nexlizet retails for $583.23 for 30, 180-10mg tablets at pharmacies. However, you may want to compare costs at different pharmacies to find the lowest price. By using a SingleCare Nexlizet coupon, cash-paying customers could reduce the drug’s cost, with prices as low as $380.14 for 30, 180-10mg tablets.
Nexlizet may be covered by some insurance plans, but the price with insurance coverage varies based on your health plan, the formulary list, and your prescription. Insurance typically helps cover some of the cost, but out-of-pocket expenses, such as copays and coinsurance, might still apply. Consult your healthcare provider or pharmacist for the most accurate prescription prices under your health insurance plan.
Some Medicare prescription drug plans may cover Nexlizet. However, Medicare coverage for prescription drugs will vary by plan and coverage stage. Consult your pharmacist or check your Medicare Part D or Advantage plan for information. For those without Medicare or with limited coverage, SingleCare may be a cost-saving option. A SingleCare Nexlizet coupon could offer a discounted price of $380.14 for 30, 180-10mg tablets, potentially offering greater savings than Medicare.
Nexlizet is a brand-name drug manufactured by Esperion. Currently, there is no generic version of Nexlizet. A generic drug containing the same active ingredients may be released once the patent for the brand name expires.
Nexlizet is a prescription medication used for managing high cholesterol, specifically targeting LDL cholesterol levels. Nexlizet may be part of a treatment plan for high cholesterol levels in patients with atherosclerotic cardiovascular disease and related conditions. Controlling cholesterol levels may help reduce the risk of heart disease complications, such as heart attack and stroke. Nexlizet works by reducing the production of cholesterol in the liver and reducing the amount of cholesterol absorbed in the small intestine.
Nexlizet is available as an oral tablet containing 180 mg of bempedoic acid and 10 mg of ezetimibe. It is typically taken as one tablet daily with or without food. If you’re taking a bile acid sequestrant, such as cholestyramine or colesevelam, you should take Nexlizet at least two hours before or at least four hours after taking the bile acid sequestrant to avoid potential interactions. Nexlizet should only be used with a valid prescription from a doctor or healthcare provider.
While Nexlizet is effective in managing cholesterol, it comes with potential side effects. Common ones include:
Muscle pain
Fatigue
Common cold symptoms
Back pain
Diarrhea
Upset stomach
Increased liver enzymes
More serious side effects are also possible, such as:
Increased risk of tendon problems or severe joint pain
High uric acid levels (hyperuricemia)
Allergic reactions like rash, hives, or swelling
Seek immediate medical help if you experience signs or symptoms of serious adverse effects. Consult a healthcare provider for medical advice or if you have any questions about the best way to avoid side effects and drug interactions.
Weight gain is not mentioned as a side effect on official drug labels for Nexlizet. There is also no direct evidence linking Nexlizet to weight gain. If you have concerns about body weight changes with the use of medicines like Nexlizet, speak with a healthcare provider. Weight gain could be caused by other factors like diet and other prescription medications.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved