What is Prevymis: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Prevymis overview

BRAND NAMES:

  • Prevymis, Prevymis

Generic Names:

  • Prevymis

Uses:

  • Prevents cytomegalovirus (CMV) infection and disease., Prevents cytomegalovirus (CMV) infection and disease.

Therapeutic Classes:

  • Antiviral, Antiviral

Forms:

  • Injectable, Tablet

How it’s taken:

  • By mouth, By injection

What is Prevymis used for?

What form(s) does Prevymis come in

  • Injectable

  • Tablet

What are common Prevymis doses?

  • Disp Pack 7 Tablets

  • Tablet 480MG

  • Box 14 Tablets

Common Prevymis prescriptions

  • Prevymis
    30 packet box

  • Prevymis
    7 tablets disp pack

  • Prevymis
    240mg tablet

  • Prevymis
    480mg tablet

  • Prevymis
    12ml of 240mg/12ml vial

  • Prevymis
    24ml of 480mg/24ml vial

How to take Prevymis

  • Swallow the tablet whole. Do not crush, break, or chew it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in its original container until you are ready to use it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Swallow the tablet whole. Do not crush, break, or chew it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in its original container until you are ready to use it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for over an hour.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for over an hour.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

What to do if you miss a dose of Prevymis

Prevymis contraindications

  • This medicine is generally considered safe for most people. Talk to your doctor if you have concerns.

  • This medicine is generally considered safe for most people. Talk to your doctor if you have concerns.

Prevymis warnings

  • Do not stop taking this medicine without talking to your doctor first.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or liver disease.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or liver disease.

Prevymis interactions

  • Do not use pitavastatin or simvastatin if you receive this medicine together with cyclosporine.

  • You should not receive this medicine together with pimozide or ergot medicines.

  • Some medicines can affect how letermovir works. Tell your doctor if you are using any of the following:Alfentanil, amiodarone, bosentan, fentanyl, midazolam, modafinil, nafcillin, phenytoin, quinidine, rifabutin, rifampin, sirolimus, tacrolimus, thioridazine, voriconazole, St John wortBlood thinner medicine (including warfarin)HIV medicine (including efavirenz, etravirine, nevirapine)Medicine to lower cholesterol (including atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin)Oral diabetes medicine (including glyburide, repaglinide, rosiglitazone)Proton pump inhibitor (including omeprazole, pantoprazole)Seizure medicine (including carbamazepine, phenobarbital, phenytoin)

  • Do not use this medicine together with pimozide or ergot medicines.

  • Do not use pitavastatin or simvastatin if you take this medicine together with cyclosporine.

  • Some medicines can affect how letermovir works. Tell your doctor if you are using any of the following:Alfentanil, amiodarone, bosentan, fentanyl, midazolam, modafinil, nafcillin, phenytoin, quinidine, rifabutin, rifampin, sirolimus, tacrolimus, thioridazine, voriconazole, St John wortBlood thinner medicine (including warfarin)HIV medicine (including efavirenz, etravirine, nevirapine)Medicine to lower cholesterol (including atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin)Oral diabetes medicine (including glyburide, repaglinide, rosiglitazone)Proton pump inhibitor (including omeprazole, pantoprazole)Seizure medicine (including carbamazepine, phenobarbital, phenytoin)

Prevymis side effects

Serious Side Effects

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Rapid weight gain, swelling in your hands, ankles, or feet

Less Serious Side Effects

  • Cough

  • Tiredness or weakness

  • Diarrhea, nausea, vomiting, stomach pain

  • Tiredness or weakness

  • Headache

  • Headache

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Diarrhea, nausea, vomiting, stomach pain

  • Cough

  • Tiredness or weakness

  • Tiredness or weakness

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